Preparation, Spectroscopy, Biological Activities and Thermodynamic Studies of New Complexes of Some Metal Ions with 2-[5-(2-Hydroxy-Phenyl)- 1,3,4-Thiadiazol-2-Ylimino]-Methyl-Naphthalen-1-Ol]

Abstract

This study describes the preparation of new series of tetra-dentate N 2 O 2 dinuclear complexes (Cr 3+ , Co 2+ , Cu 2+ ) of the Schiff base derived from condensation of 1-Hydroxy-naphthalene-2-carbaldehyde with 2amino-5-(2-hydroxy-phenyl)-1,3,4-thiadiazole. The structures of the ligands were identified using IR, UV-Vis , mass, elemental analysis and 1 H-NMR techniques. All prepared complexes have been characterized by conductance measurement, magnetic susceptibility, electronic spectra, infrared spectrum, theromgravimatric analysis (TGA) and metal analysis by atomic absorption. From stoichiometry of metal to ligand and all measurements show a octahedral geometry proposed for all complexes of the (Cr 3+ , Co 2+ , Cu 2+ ). conductivity measurement shows that of the prepared (Co 2+ , Cu 2+ ) complexes were non electrolyte but (Cr 3+ ) complexes were electrolyte. The parameters of thermodynamic, activation energy E a , enthalpy ΔH, entropy ΔS and Gibbs free energy ΔG were calculated using Coats-Redfern method by the TGA curve. The bioactivity of the prepared (LH 2 ) and its complexes have been examined with antibacterial activity which shows significant activity against some fungi and bacteria.

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“…It was indicative of octahedral geometry [20,21]. The electronic absorption of [Au (L)(H2O)Cl] peaks at (285) nm is ascribed to the π⟶π*, and (442) nm, (578) nm are ascribed to the 1 A1g→ 1 B1g, 1 A1g→ 1 A2g, respectively, which are a good evidence for square planer geometry [22], electronic transition, magnetic moments, and suggested formula of metal complexes given in Table 3.…”

Synthesis, Structure and Biological Activity Studies of New Metal Ion Complexes Based on 3-[(3-Hydroxynaphthalene-2-yl-ethylidene)-hydrazono]-1,3-dihydro-indol-2-one

“…S1 and Table 2. The 1 H-NMR spectra revealed all of the required peaks to confirm [17]. The singlet signal at δ 11.07 ppm belongs to the N-H group [18], doublet signal at δ 9.8 ppm belongs to azomethine proton N=C-H, and multiple signals at δ 8.480-6.93 ppm belong to ten aromatic protons.…”

Synthesis, Structural, Morphological Characterization, and Cytotoxicity Assays of Metal Complexes Decorated SiO2 Nanoparticles Against Breast Cancer Cell Lines (MDA-MB-231)

“…This indicates that the ligand acts as a The weak absorption bands present at frequencies below 500 cm -1 are assigned to the coordination bonds ν (M-N) 16 between the metal ion and nitrogen atom of the Munich base derivative from ciprofloxacin. The complex spectra exhibited new weak bands at a frequency range 347-368 cm -1 assigned to stretching frequency of (M-Cl) 17 for pt(IV) and Au(III) complexes. In two complexes appeared bands varying between 3383-3487 cm -1 which refers to the stretching band of water incoordination.…”