2023
DOI: 10.1016/j.heliyon.2023.e16592
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Preparations and characterizations of effervescent granules containing azithromycin solid dispersion for children and elder: Solubility enhancement, taste-masking, and digestive acidic protection

Duyen Thi My Huynh,
Huynh Thien Hai,
Nguyen Minh Hau
et al.
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Cited by 7 publications
(1 citation statement)
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“…The oral route of administration remains the most preferred due to its convenience and stability [ 32 ]. Recent advances in pharmaceutical technology led to the development of various types of tablets, such as melts [ 33 ], chewable and orodispersible tablets, oral lyophilizates and oral films, powders, granules [ 34 ], and pellets or sprinkles for reconstitution; however, generally, liquid products are preferred, especially in children under 6 years old [ 35 ]. The major barrier in the development of oral liquid formulations is the taste-masking of drugs, a hurdle that can be very costly and may not be totally achievable [ 36 ].…”
Section: The Need For Pediatric Drugsmentioning
confidence: 99%
“…The oral route of administration remains the most preferred due to its convenience and stability [ 32 ]. Recent advances in pharmaceutical technology led to the development of various types of tablets, such as melts [ 33 ], chewable and orodispersible tablets, oral lyophilizates and oral films, powders, granules [ 34 ], and pellets or sprinkles for reconstitution; however, generally, liquid products are preferred, especially in children under 6 years old [ 35 ]. The major barrier in the development of oral liquid formulations is the taste-masking of drugs, a hurdle that can be very costly and may not be totally achievable [ 36 ].…”
Section: The Need For Pediatric Drugsmentioning
confidence: 99%