Preparative Layer Chromatography

Nyiredy, Szabolcs

doi:10.1201/9780203912430.ch11

Cited by 2 publications

(1 citation statement)

References 30 publications

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“…These results are both theoretically and practically important because they indicate how medical diagnostic test strips may be fabricated without incorporating an absorbent pad, the standard means of generating sustained liquid flow in lateral flow assays sold commercially today. Finally, the approach described here for generating quasi-stationary flow is potentially applicable to thin layer chromatography, particularly recent embodiments which require continuous flow. − ,− …”

Section: Discussionmentioning

confidence: 99%

Imbibition in Porous Membranes of Complex Shape: Quasi-stationary Flow in Thin Rectangular Segments

et al. 2009

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The sustained liquid flow of a typical lateral flow assay can be mimicked by two-dimensional shaped, thin porous membranes, specifically rectangular membranes appended to circular sectors. In designing these fan-shaped devices, we have been aided by analytical equations and finite-element simulations. We show both mathematically and experimentally how a continuous increase in unwetted pore volume causes a deviation from traditional imbibition, and leads to quasi-stationary flow in the rectangular element. These results are both theoretically and practically important because they indicate how medical diagnostic test strips may be fabricated without incorporating an absorbent pad.

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