Preparedness of South Asian countries regarding Langya virus emergence: A view on the current situation

A comprehensive review of Langya virus and framework for future zoonotic disease control

“…Risk to the public -Langya is potentially an epidemic, but can be miminized 33 -South Asia is at high risk due to its proximity border to China 29 -Tropical regions such as India subcontinent is at high risk 29 -Farmers are highly at risk due to their recurrent exposure to shrew and other animals 10,23 Response from health authorities -Chinese National healthcare initiated a framework that may hamper viral spread 3 -Taiwan CDC has intensified LayV screening and surveillance methods to detect the virus by developing standardized procedures by genomic sequencing 19 -Taiwan CDC boosted up their domestic laboratories to identified quickly and picked up at the local level as well as paying close attention to any impending outbreak 19 -Collaborative efforts have been ensured by the Taiwan CDC in association with the council of Agriculture to carry out investigations on similar types of diseases in domestic species 20 Vaccination -Unavailable Prevention -Avoid direct contact with infected/high risk animal 5 -Techniques such as face masks, hand washing 5,16 -Shrew public restriction 16 Systematic approach -Public awareness and education, 29 -Strengthening surveillance and monitoring, 29 -Enhancing capacity for outbreak response, 29…”

“…-Regional collaboration and integration of research and development 29 -The one health approach is a potential approach to control LayV 17…”

“…26 To comprehensively understand the tracing and outbreak containment strategies. 29 Furthermore, the characterisation of genomic information on viruses has historically led to the development of anti-viral medications against influenza and innovative solutions to overcome resistance in certain strains. 30 The timely and comprehensive use of genomic surveillance, alongside supportive care measures, will enhance our ability to mitigate the impact of LayV and prepare for potential future challenges.…”

“…To comprehensively understand the transmission and origin of LayV, the implementation of genomic surveillance is crucial. Genomic surveillance techniques, commonly used in the detection of viral lineages and mutations, have played a pivotal role in managing various pandemics and epidemics, including COVID‐19 and the Ebola epidemic in Africa 29 . By utilising phylogenetic approaches, genomic surveillance can identify potential variants that may emerge as LayV spreads within communities.…”

“…By utilising phylogenetic approaches, genomic surveillance can identify potential variants that may emerge as LayV spreads within communities. Notably, genomic surveillance has been instrumental in tracking COVID‐19 variants like the B.1.351 and the D614G‐mutant viruses, enabling effective contact tracing and outbreak containment strategies 29 . Furthermore, the characterisation of genomic information on viruses has historically led to the development of anti‐viral medications against influenza and innovative solutions to overcome resistance in certain strains 30 .…”