The Public Health response to Zika virus induced microcephaly is largely directed at developing a protective vaccine and in devising methods for restricting human exposure to infected mosquitoes. These efforts do not address the urgent need to treat currently infected, or soon to be infected pregnant women. A key to such a strategy is understanding the alternative cellular energy (ACE) pathway. This pathway was initially identified in the defense against stealth adapted viruses. These viruses are derivatives of conventional viruses with deletion or mutation of the genes coding the major antigens normally targeted by the cellular immune system. It was subsequently shown that the ACE pathway is also effective in suppressing other viruses, including herpes simplex virus (HSV) and the human immunodeficiency virus (HIV). This review is intended to briefly explain the ACE pathway and to suggest a relatively easy initial approach at potentially enhancing the ACE pathway. It is the regular consumption of water with greatly increased dynamic (kinetic) activity induced by a natural environmental energy termed KELEA (kinetic energy limiting electrostatic attraction).