“…In the months and years following the terrorist attacks on the World Trade Center (WTC) in New York City, concerns regarding the use of various biological agents, including Y. pestis, as agents of bioterrorism were raised, and appropriate preparedness and response programs were developed. For an in-depth review of this topic, we will refer the interested reader to other publications [9,12,25,[79][80][81]. Briefly, it is well known that plague has been used as a bioweapon since the 14 th century; the perhaps most successful programs on a large scale was reportedly developed during World War II by the Japanese, and during the "cold war" by the former Soviet Union [9,25,80].…”