2020
DOI: 10.1101/2020.07.17.20156364
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Preparing For the Next Pandemic: Learning Wild Mutational Patterns At Scale For Analyzing Sequence Divergence In Novel Pathogens

Abstract: As we begin to recover from the COVID-19 pandemic, a key question is if we can avert such disasters in future. Current surveillance protocols generally focus on qualitative impact assessments of viral diversity. These efforts are primarliy aimed at ecosystem and human impact monitoring, and do not help to precisely quantify emergence. Currently, the similarity of biological strains is measured by the edit distance or the number of mutations that separate their genomic sequences, e.g. the number of mutati… Show more

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