Preparing molecularly imprinted membranes by phase inversion to separate kaempferol

Huang, Zejun; Zhang, Pin; Ye, Yun

doi:10.1002/pat.3898

Cited by 20 publications

(4 citation statements)

References 19 publications

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“…Phase-inversion process is the most commonly used method for the preparation of MIMs, in which a certain amount of template molecules and functional polymers are dissolved in a suitable solvent, after which they are scraped on support and placed in a coagulation bath or inert gas atmosphere to directly obtain a polymer membrane with molecule-specific recognition [62][63][64]. For example, Zeng et al [65] fabricated an efficient ion-imprinted membrane with platinum(IV) of template ion via non-solvent-induced phase separation (NIPS) method and realized the selective separation of platinum(IV).…”

Section: Phase-inversion Methodsmentioning

confidence: 99%

Advanced Development of Molecularly Imprinted Membranes for Selective Separation

Chen,

Wei,

Meng

2023

Molecules

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Molecularly imprinted membranes (MIMs), the incorporation of a given target molecule into a membrane, are generally used for separating and purifying the effective constituents of various natural products. They have been in use since 1990. The application of MIMs has been studied in many fields, including separation, medicine analysis, solid-phase extraction, and so on, and selective separation is still an active area of research. In MIM separation, two important membrane performances, flux and permselectivities, show a trade-off relationship. The enhancement not only of permselectivity, but also of flux poses a challenging task for membranologists. The present review first describes the recent development of MIMs, as well as various preparation methods, showing the features and applications of MIMs prepared with these different methods. Next, the review focuses on the relationship between flux and permselectivities, providing a detailed analysis of the selective transport mechanisms. According to the majority of the studies in the field, the paramount factors for resolving the trade-off relationship between the permselectivity and the flux in MIMs are the presence of effective high-density recognition sites and a high degree of matching between these sites and the imprinted cavity. Beyond the recognition sites, the membrane structure and pore-size distribution in the final imprinted membrane collectively determine the selective transport mechanism of MIM. Furthermore, it also pointed out that the important parameters of regeneration and antifouling performance have an essential role in MIMs for practical applications. This review subsequently highlights the emerging forms of MIM, including molecularly imprinted nanofiber membranes, new phase-inversion MIMs, and metal–organic-framework-material-based MIMs, as well as the construction of high-density recognition sites for further enhancing the permselectivity/flux. Finally, a discussion of the future of MIMs regarding breakthroughs in solving the flux–permselectivity trade-off is offered. It is believed that there will be greater advancements regarding selective separation using MIMs in the future.

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Section: Phase-inversion Methodsmentioning

confidence: 99%

Advanced Development of Molecularly Imprinted Membranes for Selective Separation

Chen,

Wei,

Meng

2023

Molecules

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“…Repeated experiments showed that the method has good multiplexing performance. [ 179 ] In another study, MIT was used to prepare polysulfone membranes with specific nanopores for the separation and enrichment of paclitaxel. The results showed a maximum imprinted factor of 2.28.…”

Section: Mips For Plant Active Componentsmentioning

confidence: 99%

Application of Molecularly Imprinted Polymers in Plant Natural Products: Current Progress and Future Perspectives

Zuo

et al. 2022

Macro Materials & Eng

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Plants, as a large and complex system, are rich in a variety of natural bioactive constituents. It is crucial to enrich, isolate, purify and detect these natural products. Molecularly imprinted polymers (MIPs) are a class of polymers prepared by molecularly imprinted technology (MIT) that have specific recognition sites and are complementary to templates in shape, size, and binding groups. The synthesis and polymerization mechanism of MIPs are introduced. A variety of preparation methods for MIPs have been developed. MIPs can be classified into three types: non-covalent molecularly imprinted, covalent molecularly imprinted, and semi-covalent molecularly imprinted. MIPs usually consists of five parts: template, functional monomer, cross-linker, initiator, and solvent/reagent. With the advantages of high-specificity binding ability, MIPs have shown excellent efficacy in the separation, enrichment, and purification of plant active products, such as flavonoids, polyphenols, terpenoids, and other components, especially as specific adsorbent materials. Due to the high selectivity to target the analytes, MIPs have also been used as sensors to detect the bioactive constituents in plants. Undeniably, MIPs still face undeniable limitations in the application of plant natural products. The development of MIPs with high selectivity, strong affinity, cost-effectiveness, sensitivity, and environmental friendliness are valuable and promising.

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“…The binding capacity of the resulting MIM was found to be 80 mmol g −1 , and it In the pharmaceutical and food industries, the extraction of polyphenols (such as flavonoids) from vegetable or food materials has gained great importance due to several associated health benefits of these compounds [67]. In this context, several MIMs were reported to separate and recover polyphenol compounds from these matrices [22,68,69]. Thus, Mansour et al [22] synthesized MIMs via encapsulation of prepared quercetin-MIP NPs to recover these valuable compounds from food solid wastes extracts.…”

Section: Pharmaceutical and Food Applicationsmentioning

confidence: 99%

Recent Advances in Molecularly Imprinted Membranes for Sample Treatment and Separation

et al. 2020

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This review describes the recent advances from the past five years concerning the development and applications of molecularly imprinted membranes (MIMs) in the field of sample treatment and separation processes. After a short introduction, where the importance of these materials is highlighted, a description of key aspects of membrane separation followed by the strategies of preparation of these materials is described. The review continues with several analytical applications of these MIMs for sample preparation as well as for separation purposes covering pharmaceutical, food, and environmental areas. Finally, a discussion focused on possible future directions of these materials in extraction and separation field is also given.

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Preparing molecularly imprinted membranes by phase inversion to separate kaempferol

Cited by 20 publications

References 19 publications

Advanced Development of Molecularly Imprinted Membranes for Selective Separation

Advanced Development of Molecularly Imprinted Membranes for Selective Separation

Application of Molecularly Imprinted Polymers in Plant Natural Products: Current Progress and Future Perspectives

Recent Advances in Molecularly Imprinted Membranes for Sample Treatment and Separation

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