Preputioplasty as a surgical alternative in treatment of phimosis

Osmonov, Daniar; Hamann, Claudius; Eraky, Ahmed; Kalz, Almut; Melchior, D.; Romero‐Otero, Javier

doi:10.1038/s41443-021-00505-9

Cited by 6 publications

(3 citation statements)

References 22 publications

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“…A study by El Bcheraoui et al later showed a similar trend with a very low rate of complications of 0.40% (95% CI: 0.39–0.41%) in infants, going up to 9.06% for circumcision performed between the ages of one and nine and 5.31% for males over 10 years of age ( 6 ). Additionally, several methods of preputioplasty, or surgical treatment of phimosis with preservation of the foreskin have been described ( 9 ).…”

Section: Discussionmentioning

confidence: 99%

“…Patients with phimosis, therefore, often wish to trial other methods of treatment before proceeding with circumcision. These methods include preputioplasty, or surgical treatment of phimosis with preservation of the foreskin ( 9 ) or conservative treatments, such as use of corticosteroid creams ( 2 , 10 ) with progressive stretching of the prepuce and application of stretching devices ( 11 , 12 ).…”

Section: Introductionmentioning

confidence: 99%

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Novoglan device for treatment of adult phimosis: Novoglan-01 open-label clinical trial on safety, efficacy and tolerability

Chung¹,

Polikarpov²,

Mazure³

et al. 2023

Transl Androl Urol

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Background At present, the only definitive treatment for adult phimosis is circumcision, which is a surgical removal of the prepuce. Novoglan is a novel device that could offer patients with phimosis an alternative to surgery. It is based on application of custom-moulded balloons for gradual skin remodelling and prepuce dilatation. This open-label clinical trial aimed to investigate the safety, efficacy and tolerability of the Novoglan treatment. Methods A prospective trial was conducted on 20 patients with adult phimosis recruited at Macquarie University Hospital and Princess Alexandra Hospital. After eligibility screening and enrolment, patients were provided with the Novoglan product and training. The treatment involved twice daily 10-minute applications for a duration of 4–8 weeks with patient’s degree of phimosis assessed before and at 6–8 weeks after the initiation of the treatment. Participants were also asked to complete questionnaires aimed to assess the safety and tolerability of the Novoglan treatment. Results The treatment was successful with improved foreskin retraction in 90% of patients and all patients achieving full foreskin retraction after the treatment. Ninety-five percent of patients reported reduced level of anxiety, and over 60% of patients reported reduced pain/discomfort during sexual activity or in general. Similarly, 95% of patients were moderately-to-very satisfied with the treatment and would recommend Novoglan to others. No adverse events were observed and only 15% of participants reported minor side effects. Conclusions The Novoglan-01 trial demonstrated high safety, efficacy and tolerability of the Novoglan treatment for adult phimosis and its high potential as a conservative alternative to circumcision or steroid cream treatment. Trial Registration The Novoglan-01 study has been registered with the Australia and New Zealand Clinical Trial Registry under the reference ACTRN 1262 10009 24853, dated 15 July 2021.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Novoglan device for treatment of adult phimosis: Novoglan-01 open-label clinical trial on safety, efficacy and tolerability

Chung¹,

Polikarpov²,

Mazure³

et al. 2023

Transl Androl Urol

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show abstract

“…The term preputioplasty denotes various surgical techniques directed at resolving phimosis without radical or partial circumcision. Prepuce-sparing techniques have been developed to improve the aesthetic outcomes of radical circumcision through an increased preservation of the penile foreskin [55]. Six different preputial sparing techniques have been reported for the treatment of phimosis [56], namely, the triple incision plasty, the "Heineke-Mikulicz" technique, ventral V-plasty, Y-V plasty, trident preputial plasty and Z-plasty.…”

Section: Preputial Sparing Techniquesmentioning

confidence: 99%

Phimosis in Adults: Narrative Review of the New Available Devices and the Standard Treatments

Rosato,

Miano,

Germani

et al. 2024

Clinics and Practice

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Background: Phimosis is the inability to completely retract the foreskin and expose the glans. The treatment of phimosis varies depending on the age of the patient and the severity of the disease; a great number of conservative or surgical treatments are currently available. Aim: To provide the first review summarizing the available options for the treatment of adult phimosis. Methods: A PubMed, Cochrane and Embase search for peer-reviewed studies, published between January 2001 and December 2022 was performed using the search terms “phimosis AND treatment”. Results: A total of 288 publications were initially identified through database searching. Thirty manuscripts were ultimately eligible for inclusion in this review. Conservative treatment is an option. and it includes topical steroid application and the new medical silicon tubes (Phimostop™) application for gentle prepuce dilation. Concerning the surgical approach, the gold-standard treatment is represented by circumcision in which tissue synthesis after prepuce removal can be also obtained with barbed sutures, fibrin glues or staples. Laser circumcision seems to be providing superior outcomes in terms of operative time and postoperative complication rate when compared to the traditional one. Several techniques of preputioplasty and use of in situ devices (which crush the foreskin and simultaneously create haemostasis) have been also described. These in situ devices seem feasible, safe and effective in treating phimosis while they also reduce the operative time when compared to traditional circumcision. Patient satisfaction rates, complications and impact on sexual function of the main surgical treatments are presented. Conclusion: Many conservative and surgical treatments are available for the treatment of adult phimosis. The choice of the right treatment depends on the grade of phimosis, results, complications, and cost-effectiveness.

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Take-home messages on male genital aesthetic surgery

Romero-Otero

Manfredi

2022

Int J Impot Res

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Preputioplasty as a surgical alternative in treatment of phimosis

Cited by 6 publications

References 22 publications

Novoglan device for treatment of adult phimosis: Novoglan-01 open-label clinical trial on safety, efficacy and tolerability

Novoglan device for treatment of adult phimosis: Novoglan-01 open-label clinical trial on safety, efficacy and tolerability

Phimosis in Adults: Narrative Review of the New Available Devices and the Standard Treatments

Take-home messages on male genital aesthetic surgery

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