Presacral ganglioneuroma: A case report and review of literature

Cerullo, Guido

doi:10.3748/wjg.v13.i14.2129

Cited by 40 publications

(38 citation statements)

References 16 publications

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“…Although ganglioneuromas are mostly nonfunctioning, some show metabolic activity caused by vasoactive peptides and present with such symptoms such as hypertension or diarrhea. The reported symptoms in pelvic ganglioneuromas especially in presacral location are pain, constipation or amenorrhea, but are mostly clinically silent [9]. In our patient, pelvic ganglioneuroma was incidentally detected on abdominopelvic ultrasonography performed to clarify bilateral loin pain.…”

Section: Discussionmentioning

confidence: 60%

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Diagnostic imaging findings of pelvic retroperitoneal ganglioneuroma in a child: a case report with the emphasis on initial ultrasound findings

Demir

et al. 2016

Med Ultrason

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Ganglioneuromas are rare benign tumors of neural crest origin developed along the sympathetic chain. The pelvic retroperitoneum is the rarest location of these tumors. Clinically these tumors are commonly asypmtomatic even if they reach large sizes. Here we report the radiological features of a 16 year old boy with pathologically proven retroperitoneal ganglioneuroma that was detected initially by ultrasound. Relevant literature is also discussed.

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Section: Discussionmentioning

confidence: 60%

“…The differential diagnosis list of retroperitoneal ganglioneuromas with pelvic extension include neuroblastoma, ganglioneuroblastoma, schwannoma, meningioma, or other cystic lesions [9]. FNA can be used preoperatively, but it usually leads to inconclusive diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic imaging findings of pelvic retroperitoneal ganglioneuroma in a child: a case report with the emphasis on initial ultrasound findings

Demir

et al. 2016

Med Ultrason

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“…Ganglioneuromas are frequently localized along the sympathetic chain in the posterior mediastinal, retroperitoneal, adrenal gland and cervical spinal regions (17,18). Other potential locations include the presacrum, thoracolumbar region and bone (19,20). Ganglioneuromas located in the conus medullaris, and associated with syringomyelia, are rare.…”

Section: Discussionmentioning

confidence: 99%

Conus medullaris ganglioneuroma with syringomyelia radiologically mimicking ependymoma: A case report

Wang

Dai

2015

Oncology Letters

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Abstract. Ganglioneuromas are rare, benign, well-differentiated tumors of the conus medullaris. Approximately 20 cases of spinal cord ganglioneuroma, and only 1 case of mixed chemodectoma-ganglioneuroma of the conus medullaris have been previously reported. The present study presents the case of a 38-year-old man with a histopathological diagnosis of conus medullaris ganglioneuroma. The patient presented with hypoesthesia in the lower limbs, muscle atrophy of the right lower limb and dysuria. Magnetic resonance imaging analysis led to a diagnosis of ependymoma. Histopathological analysis of the excised mass revealed typical, well-differentiated ganglion cells, consistent with a ganglioneuroma. The mass was associated with a neighboring syringomyelia. At an 18 month follow-up the patient had recovered, although some remaining difficulty in walking and urinating remained. The aim of the present report was to raise awareness that when ganglioneuromas present in unusual locations, analogous radiological findings may mislead investigators to consider more common pathologies and thus result in misdiagnosis. The present case demonstrates the importance of considering the potential differential diagnoses for neural tissue neoplasms.

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“…En ocasiones pueden secretar polipéptidos intestinalmente vasoactivos, induciendo entonces un síndrome caracterizado por diarrea, hipopotasemia y aclorhidria 28 , o testosterona, lo que conlleva virilizaciones 7 . Se han descrito ubicaciones en cualquier zona del organismo: supratentoriales 3 , cerebelosas 15 , raquídeas 4,8,10,12,13,24 , mediastínicas 27 , retroperitoneales 22 , intestinales 11 o cutáneas 6 . Cuando su localización es cercana a la medula espinal es frecuente la compresión de la misma o la tracción radicular, pudiendo causar dolor, pér-dida de fuerza o trastornos sensoriales en dependencia del nivel mielo-radicular afecto.…”

Section: Discussionunclassified

Ganglioneuroma coincidente con una extrusión discal lumbar

Martínez-Quiñones¹,

Consolini²,

Aso-Escario³

et al. 2011

Neurocirugía

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ResumenIntroducción. Los ganglioneuromas o gangliomas son tumores de los ganglios simpáticos que contienen células de la cresta neural, pudiendo aparecer en cualquier parte del organismo. Son generalmente benignos, más frecuente entre los 10 y los 40 años, pueden secretar hormonas y, en ocasiones, asociarse a trastornos genéticos, como la neurofibromatosis tipo I.Objetivo. Revisar la literatura científica relacionada con el tema y presentar un caso tratado en nuestro servicio.Discusión. La sintomatología de estas lesiones depende de su ubicación y de las sustancias vasoactivas que puedan secretar. A pesar de que son tumores benignos en su mayoría, en ocasiones pueden metastatizar. Las pruebas de imagen y de laboratorio son inespecíficas, por lo que el diagnóstico definitivo es anatomopatológico. En los casos sintomáticos el tratamiento de elección es la resección quirúrgica.Conclusión. La asociación de un ganglioneuroma y de una hernia discal lumbar es algo excepcional. El tratamiento requiere su resección quirúrgica.PALABRAS CLAVE. Ganglioneuroma. Ganglioma. Hernia discal. Ganglioneuroma coinciding with a lumbar disk herniation SummaryIntroduction. Ganglioneuromas or gangliomas are tumours of the sympathetic ganglia that contain cells of the neural crest, so they can appear in all body localizations. They are generally benign, more frequent between 10 and 40 years, may secrete hormones and, sometimes, Neurofibromatosis type I and other genetic disorders can be associated.

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Presacral ganglioneuroma: A case report and review of literature

Cited by 40 publications

References 16 publications

Diagnostic imaging findings of pelvic retroperitoneal ganglioneuroma in a child: a case report with the emphasis on initial ultrasound findings

Diagnostic imaging findings of pelvic retroperitoneal ganglioneuroma in a child: a case report with the emphasis on initial ultrasound findings

Conus medullaris ganglioneuroma with syringomyelia radiologically mimicking ependymoma: A case report

Ganglioneuroma coincidente con una extrusión discal lumbar

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