Presbyopia-correcting Intraocular Lenses in Cataract Surgery—A Focus on ReSTOR® Intraocular Lenses

Abstract

Presbyopia is defined as the inability to focus on near targets, and its correction following cataract surgery remains one of the most significant challenges for ophthalmologists and cataract surgeons.1,2 According to the World Health Organization (WHO), age-related cataracts are responsible for ~48% of world blindness, equating to ~18 million people, 3 whereas presbyopia is estimated to affect over one billion individuals globally and may be universal in those aged >65 years. 4Presbyopia arises due to the age-related loss of crystalline lens accommodation, 1,5,6 but the underlying mechanisms remain enigmatic.

Optical bench performance of AcrySof® IQ ReSTOR®, AT LISA® tri, and FineVision® intraocular lenses

“…18 FineVision has a trifocal diffractive pattern across the entire optic but is apodized. 11 In contrast, the ReSTOR +3.0 D IOLs contain a central apodized diffractive zone ending at a 3.6-mm diameter with a refractive outer zone; 8 this design makes these IOLs more strongly distance dominant at large pupil size. The ReSTOR +2.5 D has a similar 3.6 mm apodized diffractive zone that directs more energy to the distance focus and less to the near focus than the ReSTOR +3.0 IOL.…”

“…AcrySof ® IQ ReSTOR ® (Alcon Laboratories, Inc., Fort Worth, TX, USA) IOLs combine an apodized diffractive zone (for distance and near or intermediate vision) and refractive zone (for distance vision) to enhance visual acuity at multiple distances and direct light to near or distant focal points, according to lighting conditions and pupil diameter. 8 , 9 The ReSTOR +3.0 D and +2.5 D multifocal IOLs provide effective near, intermediate, and distance vision, with the ReSTOR +2.5 D IOL having a near focal point shifted toward intermediate distances. Trifocal lenses, such as the AT LISA ® tri 839MP (Carl Zeiss Meditec AG, Jena, Germany) and FineVision ® Micro F12 (PhysIOL SA, Liège, Belgium) provide an intermediate focal point in addition to near and distance focal points.…”

Visual Outcomes After Cataract Surgery: Multifocal Versus Monofocal Intraocular Lenses

“…7 The AcrySof IQ ReSTOR (Alcon Laboratories, Fort Worth, TX) is a commercially available multifocal IOL for primary implantation in the capsular bag of the eye for visual correction of aphakia secondary to removal of a cataractous lens. [8][9][10] This IOL combines a central apodized diffractive region for enhanced near vision, surrounded by a refractive region for distance vision. The AcrySof IQ Re-STOR toric IOL is a multifocal IOL that can address corneal astigmatism.…”

Evaluation of Different Power of Near Addition in Two Different Multifocal Intraocular Lenses

“…Multifocal IOLs are based on the optical principle of creating two focal planes, one for distance vision and the other for near vision [ 6 , 7 ]. AcrySof® IQ ReSTOR® (Alcon Laboratories, Inc., Fort Worth, TX, USA) IOLs combine an apodized diffractive zone (for distance and near or intermediate vision) and refractive zone (for distance vision) to enhance visual acuity at multiple distances and direct light to near or distant focal points, according to lighting conditions and pupil diameter [ 7 , 8 ].…”

“…AcrySof® IQ ReSTOR® (Alcon Laboratories, Inc., Fort Worth, TX, USA) IOLs combine an apodized diffractive zone (for distance and near or intermediate vision) and refractive zone (for distance vision) to enhance visual acuity at multiple distances and direct light to near or distant focal points, according to lighting conditions and pupil diameter [ 7 , 8 ]. The ReSTOR +3.0 D and +2.5 D multifocal IOLs provide effective near, intermediate, and distance vision, with the ReSTOR +2.5 D IOL having a near focal point shifted toward intermediate distances and demonstrating lesser glare and dysphotopsia [ 6 – 8 ].…”