Purpose-To determine the specificity of the Pediatric Vision Scanner, a binocular retinal birefringence scanner, in its intended setting, a pediatric primary care office.Methods-A total of 102 preschool children (age 2-6 years) were screened during a well-child pediatric visit using the Pediatric Vision Scanner and the SureSight Autorefractor and completed a masked comprehensive pediatric ophthalmic examination (gold standard examination).Results-Based on the gold standard examination, one child had anisometropic amblyopia, and the remaining 101 had no amblyopia or strabismus. Specificity of the Pediatric Vision Scanner was 90% (95% CI, 82%-95%) while specificity of the SureSight was 87% (95%CI, 79-93%). Combining these results with the sensitivity of the devices determined in our previous study conducted in a pediatric ophthalmology office setting, the positive likelihood ratio for the Pediatric Vision Scanner was 10.2; for the SureSight, 5.0. The negative likelihood ratio for the Pediatric Vision Scanner was 0.03; for the SureSight, 0.42, a significant difference.
Conclusions-ThePediatric Vision Scanner had high specificity (90%) in screening for amblyopia and strabismus as part of a pediatric well-child visit. Likelihood ratio analysis suggests that affected children have a high probability of being correctly identified by the Pediatric Vision Scanner. The high level of confidence conferred by Pediatric Vision Scanner screening may remove an important barrier to vision screening in pediatric primary care.Correspondence: Reed M. Jost, MS, Retina Foundation of the Southwest, 9600 North Central Expressway, Suite 200, Dallas, TX 75231 (reedjost@retinafoundation.org). Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. The authors have no financial interest in any screening device.
HHS Public Access
Author Manuscript Author ManuscriptAuthor Manuscript
Author ManuscriptAmblyopia is the most common cause of monocular visual impairment, affecting 2%-4% of children age 6 years and younger. 1,2 Delayed detection and treatment can lead to permanent vision loss. [3][4][5][6] Young children are unlikely to be aware of decreased vision in one eye; thus, the primary aim of preschool vision screening is the detection of amblyopia. Strabismus is the most common amblyogenic risk factor. 7,8 Even in the absence of amblyopia, strabismus can disrupt the development of normal binocular vision, detrimentally affect fine motor skills, and have psychosocial consequences. 9-13 Preschool vision screening could help identify children with the targeted conditions of amblyopia or strabismus wh...