Prescribing Patterns and Therapeutic Implications for Diabetic Hypertension in Bahrain

Khaja, Khalid A. J. Al; Sequeira, Reginald P.; Mathur, Vijay

doi:10.1345/aph.10399

Cited by 23 publications

(30 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A similar study as ours by Al Khaja KA et al, concluded the same. 12 In triple drug therapy metformin along with sulfonylureas and DPP-4 inhibitors as add on therapy was the commonest combination prescribed followed by voglibose and pioglitazone. This does not correspond to the results by Haghighatpanah et al, showing voglibose being the commonest choice as add on therapy to metformin and glimepiride.…”

Section: Metforminmentioning

confidence: 99%

“…(Table 1) in contrast to study by Patel B et al, which also showed positive correlation of family history (35.1%) and hypertension (70.2%) as the commonest co-morbid condition. 12 Metformin (biguanide) has advantages over insulin secretagogues by decreasing excess hepatic gluconeogenesis without raising insulin levels. It seldom leads to hypoglycemia when used as a monotherapy.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Prescribing pattern of oral anti-diabetic agents in type 2 diabetes mellitus patients in a tertiary care hospital

Sharma

Sahai

Bala

et al. 2018

Int J Basic Clin Pharmacol

View full text Add to dashboard Cite

Background: Prescription pattern studies are a tool for assessing the prescribing, dispensing and distribution of medicines. The main aim of assessing prescribing pattern is to facilitate rational use of medicines. So the main aim of the study was to assess the prescribing pattern of oral anti-diabetic agents in type 2 diabetes mellitus, to assess the rationality of the prescribed drugs and also to assess the pattern of co-morbid conditions associated with type 2 diabetes mellitus in a tertiary care hospital.Methods: This cross sectional study was conducted in the Department of Pharmacology in collaboration with Department of General Medicine. Study was conducted from 1st June 2016 to 31st Aug 2016 (3 months). A total of 100 patients were enrolled after taking written informed consent. A structured case recording form was used to record demographic details and prescription details. The rationality of prescriptions was assessed using American Diabetes Association guidelines 2015.Results: Majority of the patients were prescribed combination therapy (54%) followed by monotherapy (46%). Oral anti-diabetic agents used as monotherapy other than metformin were inappropriate. Among the patients receiving combination therapy majority were receiving a fixed dose combination which were inappropriate.Conclusions: Majority of the patients were receiving fixed dose combinations without justifiable pharmacokinetic/pharmacodynamic benefits. Such kinds of studies are required to improve rationality of prescription of drugs, decreasing morbidity and mortality of patients and decreasing the cost of treatment.

show abstract

Section: Metforminmentioning

confidence: 99%

mentioning

confidence: 99%

Prescribing pattern of oral anti-diabetic agents in type 2 diabetes mellitus patients in a tertiary care hospital

Sharma

Sahai

Bala

et al. 2018

Int J Basic Clin Pharmacol

View full text Add to dashboard Cite

show abstract

“…7,11,15,16,[18][19][20] Among the sulfonylureas, glimepiride was the most commonly prescribed drug along with metformin which is similar to studies. 10,18 Metformin is one of the safest and most cost effective drug compared to other drugs in terms of hypoglycaemia and decreasing BMI, hence this could be the most probable reason for this finding.…”

Section: Discussionmentioning

confidence: 57%

“…Most patients belonged in the age group of 41-50 yrs (40) followed by 51-60 yrs (20) age group. 98 drugs or 34.2% drugs were prescribed using their generic names.…”

Section: Male Femalementioning

confidence: 99%

Evaluation of prescribing pattern of antidiabetic drugs in medicine outpatient clinic of a tertiary care teaching hospital

Kumar

Topno

Gari

et al. 2017

Int J Basic Clin Pharmacol

View full text Add to dashboard Cite

Background: Diabetes is rapidly gaining the status of a potential epidemic in India with more than 62 million diabetics currently diagnosed with the disease. Drug utilization studies are of paramount importance for the optimization of drug therapy and promote rational drug use among health care providers. The aim of this study was to investigate the drug utilization pattern in type-2 diabetic patients. The objective of the study was to analyse the prescribing pattern of anti-diabetic drugs in a tertiary care hospital.Methods: A prospective, cross-sectional study was carried out in medicine outpatient clinic of tertiary care hospital, RIMS Ranchi for a period of 7 months. The data was analysed using WHO core indicators and Microsoft Excel 2013.Results: The total number of encounters surveyed was 94. Avg no of drugs per prescription was 3.04. Percentage of drugs prescribed by generic name was found to be 34.2%. Percentage of prescriptions was a) with antibiotics was 27.6%, b) with insulin was 14.89%, c) from essential drugs list 44.05%. Most common co morbid disease was found to be hypertension present in 27.6% cases.Most commonly use drug was found to be metformin followed by glimepiride.Conclusions: Implementation of WHO core prescribing indicators by the prescribers would help us to reduce the cost, to recognize and prevent potentially dangerous drug- drug interaction and antibiotic resistance.

show abstract

“…Among the fixed drug combinations, the study found that combination of metformin and glimepride (6.85%) was the most commonly prescribed regimen followed by metformin + glibenclamide (4.57%), metformin + pioglitazone (2.86%), metformin + gliclazide (1.71%) and metformin + voglibose (1.71%) ( Table 4). Metformin + sitagliptin was the most common combination observed by Lisha Jeeny et al study, 16 while in Al Khaja KA et al, 2001 study, 17 metformin + sulfonylurea was the most common combination. Metformin was considered to be safer and cost effective drug over others in terms of hypoglycemia could be the probable reason for this finding.…”

mentioning

confidence: 89%

Untitled

2016

IJPSR

View full text Add to dashboard Cite

Diabetes is a rapid gaining status of potential epidemic in India with more than 62 million diabetic individuals currently diagnosed with the disease. Drug utilization studies are important for the optimization of drug therapy and have received a great attention in recent years. The study of drug utilization or prescribing patterns is a component of medical audit, which seeks monitoring, evaluation and necessary modifications in the prescribing practices to achieve rational and cost effective pharmacotherapy. These studies serves as a tool of investigation for clinical pharmacology and as source of suggestive information for epidemiology. The present study aimed to evaluate the drug utilization pattern of standard antidiabetic drugs in a medicine outpatient clinic of a tertiary care teaching hospital. It's a retrospective observational epidemiological study undertaken for a period of 8 months in outpatient unit of a tertiary care Hospital, Erode. The study enrolled 175 patient prescriptions. A total of 175 patients had co-morbid conditions along with diabetes. Commonly seen co-morbid condition in the study was hypertension. The study has shown metformin as the predominantly prescribed oral antidiabetic drug both as monotherapy as well as combination therapy. Overall, monotherapy was found to be predominant over combination therapy. There was no significant increase in the prescribing of newer oral antidiabetic agents like GLP-1receptor inhibitors and DPP-4 inhibitors. Glimepride + Metformin combination was the most commonly prescribed combination. This study revealed that the pattern of antidiabetic prescription was largely comply with NICE guidelines.

show abstract

Prescribing Patterns and Therapeutic Implications for Diabetic Hypertension in Bahrain

Cited by 23 publications

References 54 publications

Prescribing pattern of oral anti-diabetic agents in type 2 diabetes mellitus patients in a tertiary care hospital

Prescribing pattern of oral anti-diabetic agents in type 2 diabetes mellitus patients in a tertiary care hospital

Evaluation of prescribing pattern of antidiabetic drugs in medicine outpatient clinic of a tertiary care teaching hospital

Untitled

Contact Info

Product

Resources

About