Prescribing Patterns of Non-Steroidal Anti-Inflammatory Drugs in Outpatient Clinics at Royal Rehabilitation Center in King Hussein Medical Center

Qoul, Kholoud Z.; Thuheerat, Ikbal N.; Ashor, Nebal Abu; Hakuz, Neris Musa Ahmad

doi:10.21608/zumj.2014.4430

Cited by 3 publications

(3 citation statements)

References 26 publications

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“…[9][10][11] The study conducted by Famotidine was the most common prescribed antiulcer agents with NSAIDs, in contrast with our study. 12 Our present study also showed the group of antiulcer agents that where prescribed most commonly along with the NSAIDs where H2 receptor antagonists i.e. ranitidine, followed by PPIs and ulcer protective agents respectively.…”

Section: Discussionsupporting

confidence: 70%

Drug utility pattern of antiulcer agents used in osteoarthritis patients at tertiary care hospital

Razvi

Lahamate

2019

Int J Basic Clin Pharmacol

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Background: Osteoarthritis is the most common form of joint disease and the leading cause of pain in elderly people. Osteoarthritis (OA) is a progressive and painful chronic disease that mainly affects knee, hand and hip joints.Aim of study was to evaluate current trend of antiulcer drugs and to assess the group of antiulcer agents use in osteoarthritis patient.Methods: A prospective observational study was conducted in a tertiary care hospital for period of twelve months in collaboration with department of orthopaedics. Patients data recorded in case report form and analysed to study prescription pattern and related information Results: Total of 630 cases were enrolled in this study. Prescribed antiulcer drugs in OA were ranitidine, omeprazole, pantoprazole, rabeprazole, sucralfate and esomeprazole. Most commonly prescribed drug was Ranitidine i.e. 80.79% followed by omeprazole i.e. 8.42% pantoprazole i.e. 3.97% rabeprazole i.e. 3.81%, sucralfate i.e. 2.53% and esomeprazole i.e. 0.48% respectively. In this study, the commonest group prescribed was H2 blockers i.e. 80.79% followed by proton pump inhibitors i.e. 16.68%, and ulcer healing agent i.e. 2.53% respectively.Conclusions: Most commonly prescribed drug was ranitidine followed by omeprazole, pantoprazole, rabeprazole, sucralfate and esomeprazole respectively. In this study, the commonest group prescribed was H2 blockers followed by proton pump inhibitors, and ulcer healing agent respectively.

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Section: Discussionsupporting

confidence: 70%

Drug utility pattern of antiulcer agents used in osteoarthritis patients at tertiary care hospital

Razvi

Lahamate

2019

Int J Basic Clin Pharmacol

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“…NSAIDs are among the most commonly prescribed class of medications globally and they account for approximately 5-10% of all medications prescribed each year [2]. For obvious reasons, elderly are among the frequent users of NSAIDs [3][4][5] and the fact that these sub-population are highly involved in prescription and non-prescription medications [6], they are highly susceptible to polypharmacy, drug-drug interactions and ultimately drug related complications and even death [7][8][9]. Serious/fatal gastrointestinal problems including ulcer and bleeding have been frequently reported with chronic use of NSAIDs [10] and thus, co-prescription of gastro-protective agents has paramount importance in preventing such risks [11].…”

Section: Introductionmentioning

confidence: 99%

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Usage and co-prescription with other potentially interacting drugs in elderly: A cross-sectional study

et al. 2020

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Globally, usage of non-steroidal anti-inflammatory drugs (NSAIDs) in elderly with chronic pain has been reported as frequent. Though NSAIDs are fundamental in maintaining their quality of life, the risk of polypharmacy, drug interactions and adverse effects is of paramount importance as the elderly usually require multiple medications for their co-morbidities. If prescriptions are not appropriately monitored and managed, they are likely to expose patients to serious drug interactions and potentially fatal adverse effects. This study was conducted to assess the appropriateness of NSAIDs use and determine the risk of NSAIDs related potential interactions in elderly. An analytical cross-sectional study was conducted among elderly outpatients (aged 60 and above) who visited three hospitals in Asmara, Eritrea, between August 22 and September 29, 2018. A stratified random sampling design was employed and data was collected using an interview-based questionnaire and by abstracting information from patients' prescriptions and medical cards. Descriptive and analytical statistics including chi-square test and logistic regression were employed using IBM SPSS (version 22). A total of 285 respondents were enrolled in the study with similar male to female ratio. One in four of all respondents were chronic NSAIDs users and NSAIDs risk practice was reported in 24%. Using chronic NSAIDs without prophylactic gastro-protective agents, self-medication, polypharmacy and drug-drug interactions were the main problems identified. A total of 322 potential interactions in 205 patients were identified and of which, 97.2% were classified as moderate, 0.6% severe and the rest were mild. Those who involved in self-medication were more likely to be exposed to drug interactions. Diabetes

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“…There are several factors that contribute to patients' preference for one drug over another such as treatment efficacy, time and chance to benefit, potential side effects, ease of administration, cost, physician and patient beliefs, drug interaction, severity of disease, and health status. 2 Despite wide clinical use of classical NSAIDs as analgesics, antipyretics, and anti-inflammatory agents their gastrointestinal toxicity (dyspepsia, peptic ulcers and gastrointestinal bleeds) is a major clinical limitation. 3 There are a variety of NSAIDs available for prescription: traditional non selective (NSAIDs), and the more selective COX-2 inhibitors (Coxibs).…”

mentioning

confidence: 99%

Analgesic prescribing trends in musculoskeletal disorders

Siddiqui

Shende

Shekhar

2018

Int J Basic Clin Pharmacol

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Background: Musculoskeletal disorders like osteoarthritis, rheumatoid arthritis, bursitis, backache, tendinitis, cervical spondylitis etc. are very commonly encountered in orthopaedic practice and are generally treated with various analgesic drugs. There are number of non-steroidal anti-inflammatory drugs (NSAIDs), opiod analgesics and also fixed dose combination (FDC) of analgesics available for the treatment of such disorders with some advantages and disadvantages of these drugs. Since few studies are there on utilization of analgesic drugs in the orthopaedic practice, this study was undertaken to determine the current prescribing trends for these disorders.Methods: It was record based observational study carried out at NKP salve institute of medical sciences, Nagpur. A total of 200 prescriptions of patients reported to orthopaedic outpatient department, with presenting complaints of musculoskeletal disorder and rheumatological conditions like osteoarthritis, rheumatoid arthritis, bursitis, backache, tendinitis, cervical spondylitis etc. were noted for the various analgesic drugs prescribed for these disorders.Results: The common age groups encountered for musculoskeletal disorders were between 41-50 years (26%) and 31-40 years (20%) followed by other age groups. The common conditions for which patient attended orthopaedic outpatient department were low backpain in 42 (21%) and osteoarthritis in 41(20.5%) patients followed by others. Aceclofenac and diclofenac were the most commonly prescribed analgesics in 25 (12.5%) and18 (9%) patients followed by other analgesics. Fixed dose combinations of NSAIDS with other NSAIDS or opoid analgesic were also commonly prescribed. Diclofenac + Paracetamol and Tramadol + Paracetamol were most commonly prescribed combinations in 30 (15%) and 19 (9.5%) patients respectively.Conclusions: As monotherapy aceclofenac and diclofenac were the most commonly prescribed NSAIDS for various musculoskeletal disorders. Also, fixed dose combinations of NSAIDS with other NSAIDS or opoid analgesic were also commonly prescribed. Diclofenac + Paracetamol and Tramadol + Paracetamol were the most commonly prescribed FDCs in our study.

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Prescribing Patterns of Non-Steroidal Anti-Inflammatory Drugs in Outpatient Clinics at Royal Rehabilitation Center in King Hussein Medical Center

Cited by 3 publications

References 26 publications

Drug utility pattern of antiulcer agents used in osteoarthritis patients at tertiary care hospital

Drug utility pattern of antiulcer agents used in osteoarthritis patients at tertiary care hospital

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Usage and co-prescription with other potentially interacting drugs in elderly: A cross-sectional study

Analgesic prescribing trends in musculoskeletal disorders

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