Prescribing statin therapy in physically (in)active individuals vs prescribing physical activity in statin-treated patients: A four-scenario practical approach

Gavilán-Carrera, Blanca; Soriano-Maldonado, Alberto; Mediavilla-García, Juan Diego; Lavie, Carl J.; Vargas-Hitos, José Antonio

doi:10.1016/j.phrs.2023.106962

Pharmacological Research

2023

DOI: 10.1016/j.phrs.2023.106962

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Prescribing statin therapy in physically (in)active individuals vs prescribing physical activity in statin-treated patients: A four-scenario practical approach

Blanca Gavilán-Carrera,

Alberto Soriano-Maldonado,

Juan Diego Mediavilla-García

et al.

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2024

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Cited by 2 publications

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“…Statins − are the most commonly prescribed cholesterol-lowering medications. They work by inhibiting an enzyme in the liver that is responsible for cholesterol production.…”

mentioning

confidence: 99%

Curcumin-Based Fixed Dose Combination Products for Cholesterol Management: A Narrative Review

Boretti

2024

ACS Pharmacol. Transl. Sci.

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Curcumin, a polyphenol compound that belongs to a class of molecules known as curcuminoids, may interact with various biological macromolecules in the body, including proteins, nucleic acids, and lipids. Curcumin-based fixed-dose combination (FDC) products enhance curcumin stability and bioavailability for better clinical use in cholesterol management. Preclinical studies on curcumin and cholesterol are mostly positive. Obstacles are the variable composition of the many different curcumin-based FDC products, the lack of standards, and the limitation of the randomized controlled trials (RCTs) conducted for specific products. Once these downfalls have been addressed, curcumin-based FDC products have great potential for cholesterol management. They can supplement the uptake of statins, reducing their dosage for the same controlling effects or even replacing them.

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“…Statins − are the most commonly prescribed cholesterol-lowering medications. They work by inhibiting an enzyme in the liver that is responsible for cholesterol production.…”

mentioning

confidence: 99%

Curcumin-Based Fixed Dose Combination Products for Cholesterol Management: A Narrative Review

Boretti

2024

ACS Pharmacol. Transl. Sci.

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Advances in statin adverse reactions and the potential mechanisms: A systematic review

Zeng,

Deng,

Luo

et al. 2024

Journal of Advanced Research

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Prescribing statin therapy in physically (in)active individuals vs prescribing physical activity in statin-treated patients: A four-scenario practical approach

Cited by 2 publications

References 50 publications

Curcumin-Based Fixed Dose Combination Products for Cholesterol Management: A Narrative Review

Curcumin-Based Fixed Dose Combination Products for Cholesterol Management: A Narrative Review

Advances in statin adverse reactions and the potential mechanisms: A systematic review

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