Prescripciones de diuréticos de asa potencialmente inapropiadas en ancianos

Availability of secondary healthcare data for conducting pharmacoepidemiology studies in Colombia: A systematic review

“…Among these, 351 articles were excluded after title screening and the abstract of the 784 remaining papers was assessed. Finally, 461 publications were excluded following the eligibility criteria and thus, 323 articles that had interpretable data and fulfilled the eligibility criteria were used for data extraction…”

“…A pharmacy dispensing company (Audifarma SA) was identified in the SLR as the most commonly used database for RWE 34,42,61,63,72,73,94‐98,100‐109,111‐115,117,118,120,122‐131,134‐141,163,168,242,301,310 . It contains demographic data, diagnosis by ICD‐10, and drug dispensation records coded by the Anatomical Therapeutic Chemical (ATC) classification, which can be used to identify comorbidities, drug‐to‐drug interactions, medication errors, adverse events, and calculate adherence rates.…”

Real-World Evidence: Pharmacoepidemiology for Daily Clinical Practice—An Experience from Colombia

“…Other studies aimed to improve the prescription of medications that are used commonly but may be incorrectly selected, such as losartan at high doses [ 14 ], or furosemide as monotherapy in patients with hypertension [ 15 ]. In the losartan study, nearly 13% of patients using this drug for the treatment of hypertension were receiving doses > 100 mg/day (no benefit added).…”

“…Then, after intervention with prescribers and decision makers, 25.4% ( n = 1832) of patients taking high doses were adjusted [ 14 ]. In the case of furosemide, we identified 160 patients aged 65 years or older who were using this medication as monotherapy for hypertension treatment, and 42% of them received an adjustment in their therapy after educational intervention with the prescribers [ 15 ].…”