Prescription appropriateness of anticoagulant drugs for prophylaxis of venous thromboembolism in hospitalized multimorbid older patients

Rossio, Raffaella; Mandelli, Sara; Ardoino, Ilaria; Nobili, Alessandro; Peyvandi, Flora; Mannucci, Pier Mannuccio; Franchi, Carlotta

doi:10.1007/s11739-022-03121-7

Cited by 4 publications

(2 citation statements)

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“…Despite these recommendations, the co-prescription with ACE-I or ARB and/or statins seems to be suboptimal in our population. Prevalence was slightly lower, but not dissimilar to that found in other Italian cohorts [14,15], but much lower than that found in other countries [36]. In many of our patients who were not co-prescribed ACE-I or ARB at hospital discharge (425/532, 80%), the use of diuretics, calcium channel antagonists and beta-blockers was preferred (data not shown).…”

Section: Discussioncontrasting

confidence: 55%

“…We obtained data from the REPOSI registry. REPOSI is a multicenter, prospective registry promoted by the Italian Society of Internal Medicine (SIMI), the Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico and the Istituto di Ricerche Farmacologiche Mario Negri IRCCS in Milan that involves about 100 internal medicine and geriatrics hospital wards throughout Italy and collects clinical and therapeutic information from in-patients aged 65 years or older [14,15]. The database includes information about sociodemographic characteristics, activities of daily living according to the Barthel Index [16], co-morbidities according to the Cumulative Illness Rating Scale (CIRS) [17] and drugs prescribed at admission, during hospital stay and at discharge.…”

Section: Settingmentioning

confidence: 99%

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Antidiabetic Drug Prescription Pattern in Hospitalized Older Patients with Diabetes

Ardoino

Mandelli

Baviera

et al. 2023

IJERPH

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Objective: To describe the prescription pattern of antidiabetic and cardiovascular drugs in a cohort of hospitalized older patients with diabetes. Methods: Patients with diabetes aged 65 years or older hospitalized in internal medicine and/or geriatric wards throughout Italy and enrolled in the REPOSI (REgistro POliterapuie SIMI—Società Italiana di Medicina Interna) registry from 2010 to 2019 and discharged alive were included. Results: Among 1703 patients with diabetes, 1433 (84.2%) were on treatment with at least one antidiabetic drug at hospital admission, mainly prescribed as monotherapy with insulin (28.3%) or metformin (19.2%). The proportion of treated patients decreased at discharge (N = 1309, 76.9%), with a significant reduction over time. Among those prescribed, the proportion of those with insulin alone increased over time (p = 0.0066), while the proportion of those prescribed sulfonylureas decreased (p < 0.0001). Among patients receiving antidiabetic therapy at discharge, 1063 (81.2%) were also prescribed cardiovascular drugs, mainly with an antihypertensive drug alone or in combination (N = 777, 73.1%). Conclusion: The management of older patients with diabetes in a hospital setting is often sub-optimal, as shown by the increasing trend in insulin at discharge, even if an overall improvement has been highlighted by the prevalent decrease in sulfonylureas prescription.

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Section: Discussioncontrasting

confidence: 55%

Section: Settingmentioning

confidence: 99%