Prescription patterns of antihypertensives in a community health centre in Mexico City: a drug utilization study

Abstract

Hypertension is highly prevalent; in Mexico, the 2012 National Health and Nutrition Survey reported a prevalence of hypertension of 31.5% in the adult population. Pharmacological treatment is the commonest intervention and has been shown to reduce cardiovascular mortality and morbidity, and total mortality. Accordingly, the type and number of antihypertensives used and the outcome — in terms of blood pressure (BP) control — are important. Therefore, our purpose is to learn the pattern of antihypertensive drug prescription and explore the determinants of BP control in an urban population in Mexico. A retrospective cross‐sectional drug utilization study was conducted. Medical records from a community health centre were searched to identify those corresponding to patients diagnosed with hypertension; information upon antihypertensives used and control of the disease was carefully retrieved. A logistic regression model was built to know the main determinants of BP control. A sample of 345 clinical records of interest was identified. Most patients received antihypertensives (86.4%); the leading medications used were angiotensin‐converting enzyme inhibitors, 63.8%; beta‐blockers (26.5%), diuretics (19.8%), angiotensin‐receptor blockers (15.8%) and calcium‐channel blockers (6.4%). Only the age (≥55 years) and BMI (>30) of the patients, and the age of the doctors (≥55 years), had an important influence on BP control. Obesity is a particular and important determinant of uncontrolled hypertension; it is worth to act on body weight, on an individual basis. As lack of control has been also tied to elderly doctors, an education programme could be envisaged.

Treating patients with hypertension in Indonesia’s primary health care centre: A challenging condition

“…CCBs were more frequently used by patients with controlled blood pressure than by patients with uncontrolled blood pressure (66.2% and 55.8%, respectively). This result was in contrast to the result by Alba-Leonel et al 17 , which showed that CCBs had a lower rate of use among individuals with controlled blood pressure than among those with uncontrolled blood pressure (4.8% vs 6.8%, respectively), although that result was insignificant. After adjusting for age, sex, and comorbidities (diabetes mellitus), CCBs were the strongest predictor of blood pressure control at the Tegal Alur II Community Health Center.…”

Prescription Pattern of Cardiovascular and/or Antidiabetic Drugs in Abuja District Hospitals

“…There was a high prescription of CCB, particularly amlodipine in FCT district hospitals. This was reported in some other studies [11,12,39,40] while CCB has been reported as least prescribed [22,41]. Agents that act on the renin-angiotensin system hold a good share of the prescription, with Lisinopril and Telmisartan leading in the class similar to other studies [15,41].…”

Antihypertensive Prescription Pattern and Compliance to JNC 7 and JNC 8 at Tertiary Care Government Hospital, Hyderabad, India: A Cross-sectional Retrospective Study

“…In a massive study conducted in China during 2004-2007 and 2011-2015, CCB were the first choice of drug followed by BB and ARB/ACEI, respectively. 12,13 In contrast, CCB were found to be least prescribed in a study conducted in northern India, 14 Bangladesh, 15 and Mexico, 16 whereas ARB, ARB, and ACEI were most preferred in these areas, respectively. Studies from Nigeria 17 and Istanbul 18 have shown maximum use of ACEI.…”