Presence of antibiotic residues in various environmental compartments of Shandong province in eastern China: Its potential for resistance development and ecological and human risk

Hanna, Nada; Sun, Pan; Sun, Qiang; Li, Xuewen; Yang, Xiwei; Ji, Xiang; Zou, Huiyun; Ottoson, Jakob; Nilsson, Lennart; Berglund, Björn; Dyar, Oliver James; Tamhankar, Ashok J.; Lundborg, Cecilia Stålsby

doi:10.1016/j.envint.2018.02.003

Cited by 348 publications

(104 citation statements)

References 92 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In a previous study, SDZ was detected in a Greek WWTP at concentrations up to 846 and 194 ng/L in influent and effluent, respectively, only during the spring season (Papageorgiou et al 2016). According to the literature, SMX is one of the most commonly detected sulfonamides in WWTPs worldwide (Hanna et al 2018). In another WWTP in Finland, SMX was found at mean concentrations of 202 and 130 ng/L in influent and effluent, respectively (Ngumba et al 2016).…”

Section: Occurrence Of Antibiotics In Influent and Effluent Samplesmentioning

confidence: 91%

Occurrence of Antibiotics in Influent and Effluent from 3 Major Wastewater‐Treatment Plants in Finland

Kortesmäki

Östman

Meierjohann

et al. 2020

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

Wastewater‐treatment plants (WWTPs) are regarded as one of the main sources of antibiotics in the environment. In the present study, the concentrations of multiple antibiotics and their metabolites belonging to 5 antibiotic classes were determined in 3 major Finnish WWTPs. An online solid phase extraction–liquid chromatography–tandem mass spectrometry method was used for the extraction and analysis of the compounds. The method was fully validated using real and synthetic wastewaters. Seven antibiotics and 3 metabolites were found in the analyzed samples. Sulfonamides were removed most efficiently, whereas macrolides usually showed negative removal efficiency during the treatment, which means that the concentrations for individual antibiotics determined in the effluent samples were higher than in the influent samples. Sulfadiazine was found at concentrations up to 1018 ng/L, which was the highest concentration of any of the detected antibiotics in influent. In the effluent samples, the highest mean concentration was found for trimethoprim (532 ng/L). The measured mass loads of the antibiotics and metabolites to the receiving waters ranged from 2 to 157 mg/d per 1000 population equivalent. The evaluated environmental risk assessment showed that clarithromycin and erythromycin might pose a risk to the environment. The present study further underlines the importance of implementing technology for efficient removal of xenobiotics during wastewater treatment. Environ Toxicol Chem 2020;39:1774–1789. © 2020 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.

show abstract

Section: Occurrence Of Antibiotics In Influent and Effluent Samplesmentioning

confidence: 91%

Occurrence of Antibiotics in Influent and Effluent from 3 Major Wastewater‐Treatment Plants in Finland

Kortesmäki

Östman

Meierjohann

et al. 2020

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

show abstract

“…Since the discovery of penicillin by Alexander Fleming in 1929 [1], antibiotics have been widely used to treat and prevent infectious diseases in humans and animals. To improve reproduction efficiency, they are also used for the feed of animals in agriculture and aquaculture [2] all over the world. In China, the total antibiotic usage in 2013 was approximately 162,000 tons [3].…”

Section: Introductionmentioning

confidence: 99%

“…Global abuse of antibiotics has aroused wide public concern, because they pose a serious threat to human health and the ecosystem. Among these antibiotics, between 30 and 90% of those used in humans and animals are excreted unchanged or as active metabolites into the environment via urine and feces [2]. In the Songhua River in Northeastern China, 12 common antibiotics were detected simultaneously in 2019 [4].…”

Section: Introductionmentioning

confidence: 99%

Trends in sensitive detection and rapid removal of sulfonamides: A review

Xie

Huang

Zheng

et al. 2020

J of Separation Science

View full text Add to dashboard Cite

Sulfonamides in environmental water, food, and feed are a major concern for both aquatic ecosystems and public health, because they may lead to the health risk of drug resistance. Thus, numerous sensitive detection and rapid removal methodologies have been established. This review summarizes the sample preparation techniques and instrumental methods used for sensitive detection of sulfonamides.Additionally, adsorption and photocatalysis for the rapid removal of sulfonamides are also discussed. This review provides a comprehensive perspective on future sulfonamide analyses that have good performance, and on the basic methods for the rapid removal of sulfonamides. K E Y W O R D Srapid removal, sample preparation techniques, sensitive detection, sulfonamides 1634

show abstract

“…Recently high concentrations of antibiotics were found in several environmental compartments that expose risk to human lives [11][12][13]. They commonly could increase the tolerance of bacteria's causing risk to humanity.…”

Section: Introductionmentioning

confidence: 99%

“…They commonly could increase the tolerance of bacteria's causing risk to humanity. Cephalosporins are antibiotics with the same basic structural requirements as penicillin [10][11][12]. These antibiotics are utilised to therapy of a variety of infections in human [14].…”

Section: Introductionmentioning

confidence: 99%

Removal of cephalexin from artificial wastewater by mesoporous silica materials using Box-Behnken response surface methodology

Panahi¹,

Ashrafi²,

Kamani³

et al. 2019

Desalination and Water Treatment

View full text Add to dashboard Cite

a b s t r a c tMesoporous silica such as MCM-41 was used as an adsorbent for the removal of cephalexin antibiotic from synthetic wastewater. In this study, MCM-41 adsorbent was synthesised and was characterised by FE-SEM, XRD, FTIR and isotherms of adsorption/desorption of N 2 . The effects of initial pH, adsorbent dose, initial adsorbate concentration, contact time and temperature on process efficiency were evaluated using Box-Behnken statistical experiment design (RSM). FTIR analysis revealed the Si-OH, H-O-H and Si-O-Si bonds are formed. According to BET surface area, MCM-41 had pores with a diameter of more than 2.0 nm and surface area of 1,097 m 2 g -1 and also XRD spectra showed the mean crystallite size of MCM-41 was 75 nm. The statistical results show that pH, adsorbent dose, initial antibiotic concentration, temperature and quadratic pH were significant and presented with probability <0.05. The optimum removal condition based on analysis of variance and the quadratic model was the initial pH of adsorbate solution fixed at 3.00, adsorbent dose 800 mg L -1 , the initial concentration of antibiotic at 50.0 mg L -1 , a temperature of 40.0°C, and at the adsorption time of 30.0 min. Under these conditions, the percentage removal of cephalexin antibiotic was 90.3%. Therefore, according to the obtained results, the mesoporous silica can be used to adsorb cephalexin antibiotic in optimal conditions designed by response surface methodology.

show abstract

Presence of antibiotic residues in various environmental compartments of Shandong province in eastern China: Its potential for resistance development and ecological and human risk

Cited by 348 publications

References 92 publications

Occurrence of Antibiotics in Influent and Effluent from 3 Major Wastewater‐Treatment Plants in Finland

Occurrence of Antibiotics in Influent and Effluent from 3 Major Wastewater‐Treatment Plants in Finland

Trends in sensitive detection and rapid removal of sulfonamides: A review

Removal of cephalexin from artificial wastewater by mesoporous silica materials using Box-Behnken response surface methodology

Contact Info

Product

Resources

About