Presence of dextranomer-hyaluronic acid (DxHA) mound on postoperative ultrasound does not predict resolution of vesicoureteral reflux

Ellsworth, Pamela; Yates, Jennifer; Caldamone, Anthony A.

doi:10.1016/j.jpurol.2010.05.008

Cited by 8 publications

(10 citation statements)

References 9 publications

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“…In different studies conducted by Lavelle et al [12] and Yucel et al [20], it was found that a subjectively proper mound appearance was highly predictive of injection success, but it should be noted that the morphology and location of the mound are not perfectly predictive of injection success or failure, as the mound seems perfectly adequate in some injections but the injection is not successful; also, the imperfect mound morphology does not necessarily imply injection failure [12]. Moreover, Ellworth PI et al showed no correlation between the presence of a mound on the post-injection ultrasound and the success of injection [19]. Some research indicated that an intraureteral injection technique in combination with hydrodistention results in higher success rates but this is controversial [9] [10] [20] [21].…”

Section: Discussionmentioning

confidence: 99%

“…By improving the injection techniques, the rate of endoscopic treatment has significantly increased as compared with open ureteral reimplantation [2]. During the recent years, many studies have been done to increase the ability to identify factors predicting success with the endoscopic subureteral injection [19]. At 2003, Puri et al [11] described "volcano" appearance as the main sign of success of injection.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A Numerical Study to Precise the Estimation of the “Good” Mound Height in Endoscopic Treatment of VUR

Shirazi¹,

Jahanabadi²,

Hooshyar³

et al. 2014

JBiSE

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Objective: To ascertain the technique and volume of injection increasing the success rate of endoscopic VUR treatment, we develop a novel method to numerically describe the relationship between intramural ureter anatomy, intravesical pressure, and the theoretical mound height needed for adequate treatment. Methods: The main purpose of this study is to construct a finite element simulation of intramural ureter and injected mound which aims to numerically define the relationship between indexes which have influence in VUR endoscopic treatment. Using linearization software and numerically simulation data, the relationship between effective indexes has been derived. Results: By linearization of the effective parameters of different finite element models, the relationship between effective parameters in filling phase is derived as: H (m) = −0.003467 (m) + 0.7864D (m) + 0.000233. This equation depicts adequate injected mound height as a function of internal diameter and intramural length, H = f(L, D). Conclusion: Using numerical simulation, we introduced the novel formula to predict the height of injected mound in endoscopic VUR treatment. As a result of this study, in order to increasing the success rate of this treatment, the ratio of mound height to intramural ureter diameter should be approximately 78%.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A Numerical Study to Precise the Estimation of the “Good” Mound Height in Endoscopic Treatment of VUR

Shirazi¹,

Jahanabadi²,

Hooshyar³

et al. 2014

JBiSE

View full text Add to dashboard Cite

show abstract

“…Conversely, some authors reported a poor correlation between mound visualization and prediction of VUR resolution [30,31]. Notwithstanding, limits of both these reports are the retrospective design of the study, US performed by radiology staff, not specifically asked to identify Dx/HA mounds, and only subsequently interpreted by the authors.…”

Section: Discussionmentioning

confidence: 99%

“…Park et al stated that assessment of the volume and location of the implant should be determined using postoperative US because the intraoperative implant morphology may change with time [8]. Ellsworth et al [30] postulated the identification of ureteral jet in relation to the mound for a proper location and they advocate the need for a real-time ultrasonography.…”

Section: Discussionmentioning

confidence: 99%

Intraoperative ultrasound-assisted approach for endoscopic treatment of vesicoureteral reflux in children

Zambaiti

Sergio

Casuccio

et al. 2017

Journal of Pediatric Surgery

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“…Whether the presence of an injection nodule on a postoperative ultrasound can predict the resolution of VUR has remained uncertain until now. Few studies have investigated the association between sonographic injection nodules and the success of endoscopic injection ( 17 – 19 ). A polydimethylsiloxane implant was identifiable in 84% of ultrasounds in one study and 86% of these had corrected VUR on postoperative VCUG ( 19 ).…”

Section: Discussionmentioning

confidence: 99%

Significance of an endoscopically injected nodule detected on ultrasound as a predictive factor for the resolution of vesicoureteral reflux

Lee

Park

et al. 2015

Experimental and Therapeutic Medicine

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Endoscopic treatment of vesicoureteral reflux (VUR) is feasible in pediatric patients. As endoscopic injection has a lower success rate than ureteral reimplantation, a postoperative voiding cystourethrogram (VCUG) is usually performed. The present study evaluated whether the presence of a nodule on noninvasive ultrasound could predict the resolution of VUR and replace invasive VCUG. Patients who received an injection of endoscopic bulking agent for VUR from January 2005 to December 2010 were evaluated retrospectively. It was evaluated whether a nodule, an echogenic mass lesion distinguished from the bladder at the ureteral orifice, was present on the ultrasound one month postoperatively. The success of the injection in the group with nodules was compared with that of the group without nodules by VCUG 3 months postoperatively. A total of 149 patients (220 ureters) met the inclusion criteria. The mean age at surgery was 3.5 years (range, 0.6–18 years). The overall success rate was 73.2%. A nodule was present in 152 cases (69.1%). The group with nodules had a higher success rate than the group without nodules (84.2%, 128/152 vs. 48.5%, 33/68, respectively; P<0.001). According to multivariate analysis, injection nodules were a predictive factor for the success of the endoscopic injection (odds ratio, 6.050; P<0.001). The failure rate increased with increasing injection volume. The sensitivity of sonographic injection nodules for predicting success was 79.5% and the specificity was 59.3%. To conclude, the presence of a postoperative nodule can predict the resolution of VUR.

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Presence of dextranomer-hyaluronic acid (DxHA) mound on postoperative ultrasound does not predict resolution of vesicoureteral reflux

Cited by 8 publications

References 9 publications

A Numerical Study to Precise the Estimation of the “Good” Mound Height in Endoscopic Treatment of VUR

A Numerical Study to Precise the Estimation of the “Good” Mound Height in Endoscopic Treatment of VUR

Intraoperative ultrasound-assisted approach for endoscopic treatment of vesicoureteral reflux in children

Significance of an endoscopically injected nodule detected on ultrasound as a predictive factor for the resolution of vesicoureteral reflux

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