Presence of Leptospire spp. in urban bats from Sincelejo, Sucre, Colombia

Victoria, Robin Jesús; Iriarte, Lilia Judith; Sampedro, A.

doi:10.20902/ijptr.2018.11303

Cited by 3 publications

(3 citation statements)

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“…In Colombia the situation is no different, two studies reported bats infected with Leptospira. In the first study, bats captured in schools belonging to the municipality of Sincelejo-Colombia were found positive for Leptospira infection [39]. In the second study, bats deposited in the Museum of Natural History of Colombia were analyzed by PCR and their kidneys were positive for Leptospira infection [40].…”

Section: Discussionmentioning

confidence: 99%

“…In Colombia, two studies have reported the presence of bats naturally infected with Leptospira. [39][40]. Due to the above characteristics, bats could act as excellent spillover of Leptospira species to the environment, favoring contamination of water and soil, serving as a direct or indirect source of infection for other animals which are the main reservoirs and disseminators of the bacteria.…”

Section: Introductionmentioning

confidence: 99%

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High Diversity of <em>Leptospira</em> Species Infecting Bats Captured in the Uraba Region (Antioquia-Colombia)

Monroy¹,

Solari²,

López³

et al. 2021

Preprint

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Leptospirosis is a globally distributed zoonotic disease caused by pathogenic bacteria of the genus Leptospira. This zoonotic disease affects humans, domestic, or wild animals. Colombia is considered an endemic country for leptospirosis; and Antioquia is the second department in Colombia with the highest number of reported leptospirosis cases. Currently, many studies report bats as reservoirs of Leptospira spp. but its prevalence in these mammals is unknown. In the present study we aimed to better understand the role of bats as reservoir hosts of Leptospira species and to evaluate the genetic diversity of circulating Leptospira species in Antioquia-Colombia. We captured 206 bats in the municipalities of Chigorodó (43 bats), Carepa (43 bats), Apartadó (39 bats), Turbo (40 bats), and Necoclí (41 bats) in the Urabá region (Antioquia-Colombia). Twenty bats were positive for Leptospira spp. infection (20/206 - 9,70%) and the species of infected bats were Carollia perspicillata, Dermatura rava, Glossophaga soricina, Molossus molossus, Artibeus planirostris, and Uroderma convexum. These species have different feeding strategies such as frugivorous, insectivores, and nectarivores. The infecting Leptospira species identified were Leptospira borgpetersenii (3/20 – 15%), Leptospira alexanderi (2/20 – 10%), Leptospira noguchii (6/20 – 30%), Leptospira interrogans (3/2 – 15%), and Leptospira kirschneri (6/20 – 30%). The results of this research show the importance of bats in the epidemiology, ecology and evolution of Leptospira in this host-pathogen association. This is the first step in deciphering the role played by bats in the epidemiology of human leptospirosis in the endemic region of Uraba (Antioquia-Colombia).

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

High Diversity of <em>Leptospira</em> Species Infecting Bats Captured in the Uraba Region (Antioquia-Colombia)

Monroy¹,

Solari²,

López³

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…Currently, more than 50 species of infected bats with Leptospira have been reported in different countries, including Peru [ 23 ], Brazil [ 24 ], Argentina [ 25 ], Australia [ 26 ], Comoros island and Madagascar [ 27 ], Reunion Island [ 28 ], Mayotte Island [ 29 ], Indonesia [ 30 ], Malaysia [ 31 ], Tanzania [ 32 ], Trinidad [ 33 ], Sudan [ 34 ], Democratic Republic of Congo [ 35 ], Africa [ 36 ], and Azerbaijan [ 37 ]. In Colombia, two studies have reported the presence of bats naturally infected with Leptospira [ 38 , 39 ]. Due to the above characteristics, bats could act as excellent spillover of Leptospira species to the environment, favoring contamination of water and soil, serving as a direct or indirect source of infection for other animals, which are the main reservoirs and disseminators of the bacteria.…”

Section: Introductionmentioning

confidence: 99%

High Diversity of Leptospira Species Infecting Bats Captured in the Urabá Region (Antioquia-Colombia)

et al. 2021

View full text Add to dashboard Cite

Leptospirosis is a globally distributed zoonotic disease caused by pathogenic bacteria of the genus Leptospira. This zoonotic disease affects humans, domestic animals and wild animals. Colombia is considered an endemic country for leptospirosis; Antioquia is the second department in Colombia, with the highest number of reported leptospirosis cases. Currently, many studies report bats as reservoirs of Leptospira spp. but the prevalence in these mammals is unknown. The goal of this study was to better understand the role of bats as reservoir hosts of Leptospira species and to evaluate the genetic diversity of circulating Leptospira species in Antioquia-Colombia. We captured 206 bats in the municipalities of Chigorodó (43 bats), Carepa (43 bats), Apartadó (39 bats), Turbo (40 bats), and Necoclí (41 bats) in the Urabá region (Antioquia-Colombia). Twenty bats tested positive for Leptospira spp. infection (20/206—9.70%) and the species of infected bats were Carollia perspicillata, Dermanura rava, Glossophaga soricina, Molossus molossus, Artibeus planirostris, and Uroderma convexum. These species have different feeding strategies such as frugivorous, insectivores, and nectarivores. The infecting Leptospira species identified were Leptospira borgpetersenii (3/20–15%), Leptospira alexanderi (2/20–10%), Leptospira noguchii (6/20–30%), Leptospira interrogans (3/20–15%), and Leptospira kirschneri (6/20–30%). Our results showed the importance of bats in the epidemiology, ecology, and evolution of Leptospira in this host-pathogen association. This is the first step in deciphering the role played by bats in the epidemiology of human leptospirosis in the endemic region of Urabá (Antioquia-Colombia).

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Pathogenic Leptospira Species in Bats: Molecular Detection in a Colombian Cave

et al. 2022

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Leptospirosis is caused by pathogenic Leptospira spp., which can be found in nature among domestic and wild animals. In Colombia, the Macaregua cave is known for its bat richness; thus, because bats are reservoir hosts of human microbiological pathogens, we determined if the Macaregua cave bats harbored Leptospira in the wild. A total of 85 kidney samples were collected from three bat species (Carollia perspicillata, Mormoops megalophylla, and Natalus tumidirostris) to detect Leptospira spp. The 16S rRNA gene was targeted through conventional PCR and qPCR; in addition, the LipL32 gene was detected using conventional PCR. Obtained amplicons were purified and sequenced for phylogenetic analysis. The Leptospira spp. 16S rRNA gene was detected in 51.8% bat kidneys, of which 35 sequences were obtained, all clustering within the pathogenic group. Moreover, 11 sequences presented high-identity-values with Leptospiranoguchii, Leptospiraalexanderi, Leptospiraborgpetersenii, Leptospirakirschneri, and Leptospiramayottensis. From the 16S rRNALeptospira spp.-positive population samples, 28 amplified for the LipL32 gene, and 23 sequences clustered in five different phylogenetic groups. In conclusion, we detected the circulation of different groups of Leptospira spp. sequences among cave bats in the wild; some sequences were detected in more than one bat specimen from the same species, suggesting a conspecific transmission within the cave.

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Presence of Leptospire spp. in urban bats from Sincelejo, Sucre, Colombia

Cited by 3 publications

References 14 publications

High Diversity of <em>Leptospira</em> Species Infecting Bats Captured in the Uraba Region (Antioquia-Colombia)

High Diversity of <em>Leptospira</em> Species Infecting Bats Captured in the Uraba Region (Antioquia-Colombia)

High Diversity of Leptospira Species Infecting Bats Captured in the Urabá Region (Antioquia-Colombia)

Pathogenic Leptospira Species in Bats: Molecular Detection in a Colombian Cave

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