Presence of Sandaracopimaric and Δ⁸⁽⁹⁾-Isopimaric Acids in Pine Oleoresin

Resin acid composition of pine oleoresins

“…DISCUSSION About 2 billion pounds of pine oleoresin and rosin are used each year as raw materials for making paints, varnishes, paper size, and other commercial products. Gas chromatography has been used for the isolation and identification of several resin acids from pine oleoresin and rosin (7), and reports on the composition of the acid fraction of several species of pine have been published (1, 2, 6, 9-14).…”

The chemistry and biology of natural ribomimetics and related compounds

“…However, the presence of both genes in the anisomycin BGC and the identification of the glucosylated intermediates in the AniG mutant strongly suggest that the glucosylation-deglucosylation steps are involved. The timing of the glycosylation step in the pathway and the selectivity of the glycosyltransferase enzyme were confirmed by in vitro enzymatic assay where the recombinant AniO could only glycosylate the AniP product DHPP (87) and not any other intermediates. In addition, the transamination reaction by AniQ took place more efficiently with a glucosylated substrate.…”

“…As expected from its chemical structure, dl -tyrosine was found to be efficiently incorporated into anisomycin. 87 The biosynthetic gene cluster of anisomycin was later identified in S. hygrospinosus var. beijingensis , another producer of anisomycin, using a bioactivity-guided genomic library screening approach.…”

Decoding the chemical language of Suillus fungi: genome mining and untargeted metabolomics uncover terpene chemical diversity

“…4B , there is a high similarity between the tandem mass spectra for the sandaracopimaric acid analytical standard and the Suillus -derived metabolite. Previous work studying pine resin and plant tissue has shown that these chemical fractions also have high concentrations of other non-volatile diterpenoids, including abietic acid, pimaric acid, and isopimaric acid ( 33 – 35 ). To assess tandem mass spectra fragmentation similarity between the isomers sandaracopimaric and abietic acid, we purchased a commercial standard for abietic acid (Sigma Aldrich, CAS No.…”