2021
DOI: 10.1097/cce.0000000000000320
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Presence of Spontaneous Echo Contrast on Point-of-Care Vascular Ultrasound and the Development of Major Clotting Events in Coronavirus Disease 2019 Patients

Abstract: Objectives: The presence of spontaneous echo contrast on ultrasonography is a predisposition to increased thromboembolic risk. The purpose of this study was to assess for the prevalence and consequences of spontaneous echo contrast on point-of-care vascular ultrasound in coronavirus disease 2019. Design, Setting and Patients: This was a retrospective cohort study of 39 adult patients admitted to the ICU with a confirmed coronavirus disease 2019 diagnosi… Show more

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Cited by 6 publications
(7 citation statements)
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“… [47] Another study found that patients with spontaneous echo contrast had hyper viscosity and thrombotic events. [50] In general, there was no association between spontaneous echo contrast with the D Dimer value or NEWS 2 score. This further reaffirms the fallacy of using d- Dimer based anticoagulation and adds value to include the COVID-19 POCUS protocol to identify thrombosis of common femoral or popliteal veins.…”
Section: Discussionmentioning
confidence: 87%
“… [47] Another study found that patients with spontaneous echo contrast had hyper viscosity and thrombotic events. [50] In general, there was no association between spontaneous echo contrast with the D Dimer value or NEWS 2 score. This further reaffirms the fallacy of using d- Dimer based anticoagulation and adds value to include the COVID-19 POCUS protocol to identify thrombosis of common femoral or popliteal veins.…”
Section: Discussionmentioning
confidence: 87%
“…SEC in the IJVs is positively correlated with a higher plasma fibrinogen level, high-sensitivity C-reactive protein, and prior stroke, and in those critically ill with coronavirus disease, the presence of venous SEC was associated with 'clotting events'. 20,21 Most subjects maintained the normal antegrade direction of IJV flow bilaterally. However, slow retrograde flow was observed in two individuals during spaceflight.…”
Section: Discussionmentioning
confidence: 97%
“…SEC in the IJVs is positively correlated with a higher plasma fibrinogen level, high-sensitivity C-reactive protein, and prior stroke, and in those critically ill with coronavirus disease, the presence of venous SEC was associated with ‘clotting events’. 20,21…”
Section: Discussionmentioning
confidence: 99%
“…The effect of spontaneous contrast enhancement of vein lumen in patients with coronavirus disease is associated with increased viscosity, i.e., blood clotting, an increase in the frequency of thrombotic events and complications. Assessing the presence of spontaneous echo contrast (SC) on ultrasound is a promising strategy and may be a useful alternative to laboratory measurements [39].…”
Section: Discussionmentioning
confidence: 99%