Present status and future perspectives of preoperative portal vein embolization

A systematic review of contralateral liver lobe hypertrophy after unilobar selective internal radiation therapy with Y90

“…25,26 However, in these studies, the mean increase in percentage of FLR achieved in the PVE + TACE arms was only 7.3-22%, which was significantly less than that usually reported with PVE in the literature. 7 The current systematic review demonstrated that unilobar Y90 SIRT resulted in significant hypertrophy of the contralateral liver lobe. However, all studies to date have been retrospective and observational in nature.…”

“…In head-to-head comparisons, the two techniques have been shown provide equivalent degrees of hypertrophy, 5,6 estimated to be between 10 and 46% at 2-8 weeks. 7 PVE is thus preferentially utilised as it is minimally invasive in nature and avoids a laparotomy. Presently, selective internal radiation therapy (SIRT) with Yttrium-90 (also known as radioembolization) has become an increasingly utilized treatment modality for locally advanced liver tumours, with radiological tumour response rates of between 42 and 70% reported.…”

«saving» a Two-Stage Liver Resection by the Alpps Type

“…При этом через 7-8 нед после редукции кровотока в правой ветви во-ротной вены наступает гипертрофия остающихся от-делов печени, что позволяет выполнить оперативное вмешательство в радикальном объеме. Однако реа-лизовать 2-й этап запланированной двухэтапной ре-зекции печени удается не более чем у 70-75% паци-ентов, что, в первую очередь, связано с отсутствием гипертрофии остающихся отделов печени (FLR) [1][2][3]. Исследователями было доказано, что при FLR мень-ше 20% при состоятельной паренхиме печени и 40% при функциональном (неоадъювантная химиотера-пия, цирроз) поражении печени реализация хирур-гических вмешательств сопряжена с крайне высоким риском развития печеночной недостаточности [4][5][6].…”

Impact of timing of elective abdominal surgery on postoperative liver function

“…1,2 Despite recent advances in surgical techniques and intensive care management, liver function damage is still a challenging problem after elective surgery.…”