Present Status of ABO Incompatible Kidney Transplantation in Japan-Lessons From More Than 2,400 Cases to Date-.

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“…An immunosuppression desensitization protocol using Overall patient and graft survival rates were 97% and 94% at 1 year, 93% and 86% at 5 years, 90% and 71% at 10 years, and 73% and 52% at 20 years ( Figure 2). 2 The patient and graft survival rates in 2001 to 2012 (n = 1985) were 98% and 96% at 1 year, 95% and 90% at 5 years, and 93% and 81% at 10 years. These rates were significantly better than 92% and 82% at 1 year, 86% and 70% at 5 years, and 83% and 55% at 10 years in 1989 to 2000 (n = 449) (Figures 3 and 4).…”

“…These rates were significantly better than 92% and 82% at 1 year, 86% and 70% at 5 years, and 83% and 55% at 10 years in 1989 to 2000 (n = 449) (Figures 3 and 4). 2 The graft survival rate in 1989 to 2000 remarkably decreased within 1 year of transplantation ( Figure 4). In contrast, the graft survival rate in 2001 to 2012 did not decrease as much as that in 1989 to 2000 (Figure 4).…”

“…2 In 2011, there were 293 ABOi performed but the number decreased to 196 in 2012 ( Figure 1). 2 A total of 2434 cases of ABOi were registered with the Japan ABO-Incompatible Transplantation Committee.…”

“…2 In 2011, there were 293 ABOi performed but the number decreased to 196 in 2012 ( Figure 1). 2 A total of 2434 cases of ABOi were registered with the Japan ABO-Incompatible Transplantation Committee. 2 The rate of ABOi (n = 196) in living-donor kidney transplantations in Japan (n = 1431) is 13.7%.…”

“…2 A total of 2434 cases of ABOi were registered with the Japan ABO-Incompatible Transplantation Committee. 2 The rate of ABOi (n = 196) in living-donor kidney transplantations in Japan (n = 1431) is 13.7%. An immunosuppression desensitization protocol using Overall patient and graft survival rates were 97% and 94% at 1 year, 93% and 86% at 5 years, 90% and 71% at 10 years, and 73% and 52% at 20 years ( Figure 2).…”