Presentación no habitual del linfoma folicular

Télles, Arturo Cortés; Sandoval, Ricardo

doi:10.1016/j.arbres.2010.07.008

Cited by 3 publications

(3 citation statements)

References 6 publications

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“…Malignant chylothorax represents more than 50% of the cases of non-traumatic chylothorax, with most of them being caused by lymphoproliferative disorders [1]. We assume that in the cases described in this article, the function/integrity of the thoracic duct and the subsequent leakage of lymph or impaired drainage was due to infiltration or external compression by a tumor [3]. The treatment of chylothorax is usually long and depends on the type of chylothorax, its duration, extent of chyle loss, and the overall condition of the patient.…”

Section: Discussionmentioning

confidence: 99%

“…For instance, a female patient with a 16 cm retroperitoneal lymphadenopathy was hospitalized for 58 days while a male patient with a small mediastinal and retroperitoneal lymphadenopathy (2 cm) needed 87 days of hospitalization. Generally, advanced stages of the disease in which chylothorax occurred obviously prevailed (Table 1) [3, 16].…”

Section: Discussionmentioning

confidence: 99%

“…Chylothorax is the accumulation of chyle in the pleural cavity. One of the causes of the disturbed function of the thoracic duct is the direct infiltration or compression by a tumor [1–3]. As a result, chyle leaks and accumulates within the pleural cavity.…”

Section: Introductionmentioning

confidence: 99%

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Experiences in the treatment of refractory chylothorax associated with lymphoproliferative disorders

Pospiskova¹,

Smolej²,

Belada³

et al. 2019

Orphanet J Rare Dis

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BackgroundChylothorax is a rare condition which can be associated with malignant lymphoproliferative disorders (LPDs). We retrospectively analyzed the results of the conservative treatment of 10 patients with persistent non-traumatic malignant chylothorax.ResultsConservative treatment lead to a decline of chylothorax after mean of 66 days and consisted of the treatment of the underlying disease and of simultaneous long-term supportive care (drainage of the thoracic cavity, dietary measures and nutrition management). In most cases (80%), chylothorax disappeared only after a successful therapeutic response of the underlying disease. Low-dose radiotherapy had very good effects in two patients.ConclusionConservative treatment of malignant chylothorax can be considered a suitable method. Based on our results, successful treatment of the lymphoproliferative disorder seems to be a very important factor for the disappearance of chylothorax.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Experiences in the treatment of refractory chylothorax associated with lymphoproliferative disorders

Pospiskova¹,

Smolej²,

Belada³

et al. 2019

Orphanet J Rare Dis

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A rare case of bilateral chylothorax: a diagnostic challenge—follicular lymphoma versus primary effusion lymphoma

et al. 2015

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SUMMARYChylothorax is most common on the left side owing to the position of the thoracic duct. Malignancy-associated chylothorax is not uncommon. However, bilateral chylothorax is rare and malignancy should be a consideration in absence of trauma. We report a case of a patient with follicular lymphoma who presented with bilateral pleural effusion; pleural fluid analysis confirmed chylothorax. The patient did not have any significant peripheral or axial lymphadenopathy, which made the diagnosis difficult in absence of histopathology. Pleural fluid analysis was negative for malignant cells, however, the flow cytometry markers were suggestive of follicular lymphoma. Primary effusion lymphoma, which could have been another possibility, was ruled out by the flow cytometry markers. We conclude that pleural fluid flow cytometry markers play an important role where there is no significant lymphadenopathy and in absence of histopathological diagnosis. This demands further evaluation. BACKGROUND

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Chylothorax in a Patient with Hodgkin's Lymphoma: A Case Report and Review of the Literature

Janjetovic

Janning

Daukeva

et al. 2013

Tumori

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Background. Chylothorax is defined as chyle entering the pleural space. The most common causes of chylothorax are lymphoma followed by bronchogenic carcinoma and trauma. Case report. We report a case of chylothorax in a patient with Hodgkin's lymphoma. A 28-year old man was admitted to the hospital with exertional dyspnea and dry cough. A chest X-ray showed the large opacity on the left side suggesting to the presence of pleural effusion. Methods. The effusion was drained, and biochemical tests of the pleural fluid revealed high contents of triglycerides and, hence, confirmed the diagnosis of chylothorax. Cytology of the pleural fluid showed no evidence of Hodgkin's cells. Computer tomography scans of the chest and abdomen exhibited the presence of a soft tissue mass located in the left mediastinum. Mediastinal mass biopsy led to diagnosis of Hodgkin's lymphoma of the nodular sclerosis subtype. The patient received the standard treatment with two cycles of chemotherapy with prednisolone, doxorubicin, cyclophosphamide, vincristine, bleomycin, procarbazine, and etoposide (BEACOPP), followed by an additional two cycles of therapy with doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD). Results. After one cycle of chemotherapy, chylothorax initially decreased. Unfortunately, during the following courses of chemotherapy, the pleural effusion reoccurred and repeated pleural taps were necessary. According to the treatment protocol, radiation of the mediastinal bulk was performed after chemotherapy. Now, nearly one year after completion of radiotherapy, the chylothorax has significantly regressed and no further thoracocenteses were necessary. Conclusion. The case reveals an example of left-sided chylothorax as the first manifestation of Hodgkin's lymphoma in a young patient. In this case, radiotherapy was shown to be an effective treatment option for lymphoma-associated chylothorax unresponsive to chemotherapy.

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Presentación no habitual del linfoma folicular

Cited by 3 publications

References 6 publications

Experiences in the treatment of refractory chylothorax associated with lymphoproliferative disorders

Experiences in the treatment of refractory chylothorax associated with lymphoproliferative disorders

A rare case of bilateral chylothorax: a diagnostic challenge—follicular lymphoma versus primary effusion lymphoma

Chylothorax in a Patient with Hodgkin's Lymphoma: A Case Report and Review of the Literature

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