Presentation and pattern of childhood renal diseases in Gusau, North-Western Nigeria

Garba, Bilkisu Ilah; Muhammad, Abdullahi Salisu; Obasi, A B; Adeniji, Akeem Oladiran

doi:10.7196/sajch.2017.v11i2.1222

Cited by 6 publications

(13 citation statements)

References 9 publications

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“…Male predominance in the index study is in keeping with previous studies [5,32,23]. It has been documented that male children are more susceptible to most diseases compared to female children [39].…”

Section: Discussionsupporting

confidence: 86%

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Pattern of Childhood Renal Diseases in Aba, South East Nigeria

Okoronkwo¹,

Chapp-Jumbo²,

Onyire³

et al. 2020

AJP

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Section: Discussionsupporting

confidence: 86%

“…The overall prevalence of renal disorders in this study is lower than reported from other centres in and outside Nigeria [3,4,21,[32][33][34][35][36][37]. It is however higher than the 1.1% and 1.3% from Rivers [42] and Delta [2] states, in eastern Nigeria respectively.…”

Section: Discussioncontrasting

confidence: 76%

Pattern of Childhood Renal Diseases in Aba, South East Nigeria

Okoronkwo¹,

Chapp-Jumbo²,

Onyire³

et al. 2020

AJP

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“…We found that kidney disease represented 7.8% of all pediatric admissions to the National Referral Hospital, a proportion similar to studies from neighboring countries 1,17 . The proportion of kidney disease in our center was higher than those reported from African countries which ranged from 1.6 to 3.8% 4,5,[18][19][20] . This variation could be due to differences in clinical and laboratory capacities to diagnose kidney diseases in different regions and also methodological variation related to data collection in our study.…”

Section: Discussioncontrasting

confidence: 66%

Pattern and short-term outcome of pediatric kidney disease at national referral hospital in Bhutan: an observational study

Sonam¹,

Lhadon²,

Choden³

et al. 2022

Bhutan Health Journal

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Introduction: The epidemiology of kidney diseases in children can vary widely across geographic regions. The main purpose of this study was to determine the pattern and short-term outcome of kidney disease among children hospitalized at the national referral hospital in Bhutan. Methods: All admitted children aged one month to 12 years with kidney disease, from January to December 2018, were included in the study. Diagnostic criteria were applied to all the patients on admission to determine study eligibility and subsequent demographic and clinical data were collected using a structured interviewer administered pro forma. Results: A total of 128 (7.8%) children met diagnostic criteria for kidney disease among 1648 hospitalized children during the study period. The median age at presentation was 2.5 years (interquartile range 0 to 8). The commonest disease was acute kidney injury (48, 37.5%) followed by acute glomerulonephritis (37, 28.9%), urinary tract infection (37, 28.9%), congenital anomalies of kidney and urinary tract (11, 8.6%) and nephrotic syndrome (11, 8.6%). Median duration of hospital stay was 8 days (IQR 4 to 14.8). Four (3.1%) patients were referred to India for specialist care, 5 (3.9%) underwent dialysis and 28 (21.9%) died. Of the 28 patients who died, 26 (92.9%) had acute kidney injury and 2 (7.1%) had chronic kidney disease. Conclusions: Pediatric kidney diseases comprise a significant proportion of disease burden at the national referral hospital. Education of primary healthcare providers about the epidemiologic burden of pediatric kidney diseases is needed to reduce kidney-related morbidity and mortality.

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“…Acute post-infectious AGN accounted for 8.9% of childhood renal admissions in this study and did not vary much from the previous findings of 11.4% and 11.6% from Ibadan 23,28 11.4% from Port-Harcourt 29 , 10% from Lagos 25 and Abuja 30 but much less than the figures reported from Zaria (38.1%), Jos (37.7%), Enugu (31.9%) and Kano (24.8%) 31,6,32,33 . The findings from Benin (20%) and Gusau (24%) are in between, 34,10 These data seem to suggest that children from the northern part of Nigeria are at greater risk for AGN and this most probably may due to climatic and socioeconomic factors.…”

Section: Discussionmentioning

confidence: 78%

“…Acute glomerulonephritis (AGN) is one of the oldest and most common non-suppurative renal disease conditions seen in childhood. It is a common cause of childhood morbidity and mortality in low and middle income countries (LMICs) [1][2][3][4][5][6][7][8][9][10] AGN could arise as a primary renal disorder, 11,12 or could be secondary to a systemic disease. 13 Acute post-streptococcal glomerulonephritis (APSGN) is the prototype of AGN but a sub-set of acute post-infectious glomerulonephritis (APIGN) which is mostly caused by group A β -hemolytic streptococcus, but could be caused by any infectious agent (bacteria, virus, fungal, parasite).…”

Section: Introductionmentioning

confidence: 99%

Childhood acute glomerulonephritis in Ibadan Nigeria

Asinobi¹,

Ademola²,

Nwankwo³

2020

Nig. J. Paed.

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Background: Acute glomerulonephritis (AGN) is an important cause of mortality and morbidity in children in developing countries while its incidence has declined in the developed world. This study was to document its present impact in our setting.Aim: To evaluate the sociodemographic features and clinical outcomes in children hospitalized for AGN in the Paediatric Nephrology Unit of the University College Hospital, Ibadan.Subjects and Methods: This was a descriptive analytical study of children aged 2 to 14 years admitted with AGN between 2007 and 2019. Their sociodemographic data, clinical features, complications and outcome were analysed.Results: AGN accounted for 116 (8.9%) of new renal cases admitted over the period. Seventy-four (63.8%) were male, mean age (SD) was 8.2 (3.3) years and peak age incidence between 5 and 9 years. Average annual hospital incidence rose from 4-5 new cases to 8-9 new cases/annum with an upsurge to 17 cases in 2019. Highest yearly monthly incidence was between June and December. Forty -five out of 50 (90%) evaluated subjects were in the middle/ low socioeconomic classes. Stage 2 hypertension occurred in 30/50 (60%) with hypertensive crises in 24%. RPGN occurred in 6/50 (12%) of cases accounting for 5 of the 8 dialysed patients and 4 of the 5 deaths. The case fatality rate was 4.3%.Conclusion: The study showed a progressive increase in the hospital incidence of AGN.RPGN was a major risk factor for death in children with AGN and therefore requires a high index of suspicion and an appropriate early intervention. Key words: Childhood, Acute Glomerulonephritis (AGN), Postinfectious AGN, Rapidly progressive glomerulonephritis (RPGN), Hypertensive crises, Outcome

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Presentation and pattern of childhood renal diseases in Gusau, North-Western Nigeria

Cited by 6 publications

References 9 publications

Pattern of Childhood Renal Diseases in Aba, South East Nigeria

Pattern of Childhood Renal Diseases in Aba, South East Nigeria

Pattern and short-term outcome of pediatric kidney disease at national referral hospital in Bhutan: an observational study

Childhood acute glomerulonephritis in Ibadan Nigeria

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