Presentation of primary mediastinal masses in Ibadan

Adegboye, V O; Ogunseyinde, AO; Obajimi, M O; Ogunbiyi, Olufemi J.; Brimmo, AI; Oa, Adebo

doi:10.4314/eamj.v80i9.8747

Cited by 9 publications

(11 citation statements)

References 16 publications

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“…This contrasts with earlier positions where lymphomas, thymic tumours and thyroid masses were found in reducing order [7,13].…”

Section: Discussioncontrasting

confidence: 95%

“…This constituted an annual hospital-based occurrence of 7.6 cases and it was nearly double the occurrence of mediastinal masses in Ibadan, a centre 120 kilometres North-east of our centre [7] within 51 -60…”

Section: Discussionmentioning

confidence: 85%

“…While an earlier report from Ibadan, southwest Nigeria confirmed lymphomas as the commonest primary mediastinal masses, [7] Lam and his colleagues [6] in Singapore found neurogenic tumour as the commonest his-tologic variant. Some of the rare tumours of the mediastinum include sarcoma of follicular dendritic cells in the posterior mediastinum, non seminomatous germ cell tumour, adenomatoid tumour, mediastinal extramedullary haemopoietic tumour, thoracic duct cysts and cervicothoracic schwannoma.…”

Section: Introductionmentioning

confidence: 94%

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Mediastinal Masses: Pathophysiological Issues and Management Challenges in a Developing World

Thomas¹,

Ogunleye²

2011

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Context: Mediastinal masses occur worldwide. Compartmental occurrence and pathological variants vary widely, hence, the need for more studies. AIM: The study was conducted to further shed light on pathophysiological and current management challenges of mediastinal masses. Settings and Design: It was a prospective hospital based study spanning a period of 5 years. Methods and Materials: We gathered patients in series noting their ages and sex, presenting symptoms, investigation reports, treatment modalities and associated postoperative complications. Statistical Analysis Used: Data was analysed manually looking at frequency distribution, correlation of malignancy with compartment involved and duration of symptoms against incidence of malignancy. Results: We saw 38 patients with significant male preponderance. Most tumours were in anterior mediastinum and population distribution was leptokurtic. Conclusions: Population distribution of mediastinal masses is leptokurtic. The second to the fourth decades of life are mostly affected. There was no correlation between occurrence of malignancy and the mediastinal compartment involved. Most benign tumours are symptomatic and duration of symptoms is not discriminatory between benign and malignant variants. Occurrence of malignancy had no bearing with duration of symptoms. If less than two months, it became significant at sixth month when benignity was positively correlated with long duration of symptoms.

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“…This contrasts with earlier positions where lymphomas, thymic tumours and thyroid masses were found in reducing order [7,13].…”

Section: Discussioncontrasting

confidence: 95%

Section: Discussionmentioning

confidence: 85%

Section: Introductionmentioning

confidence: 94%

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Mediastinal Masses: Pathophysiological Issues and Management Challenges in a Developing World

Thomas¹,

Ogunleye²

2011

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“…The demographic profile of the patients in our study was similar to other studies34. Most of the lesions were in the anterior compartment similar to other studies56. In the present study, 62.1 per cent of lesions were neoplastic in nature, of which benign lesions were more common than malignant lesions as has been reported earlier57.…”

Section: Discussionsupporting

confidence: 90%

“…Most of the lesions were in the anterior compartment similar to other studies56. In the present study, 62.1 per cent of lesions were neoplastic in nature, of which benign lesions were more common than malignant lesions as has been reported earlier57. However, some other studies reported 60-70 per cent of mediastinal masses to be malignant46.…”

Section: Discussionsupporting

confidence: 89%

Morphological spectrum of mediastinal lesions with special emphasis on evaluation of needle biopsy

Aggarwal

Rao

Chopra

et al. 2016

Indian Journal of Medical Research

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Background & objectives: Mediastinal lesions are uncommon and are infrequently encountered in routine clinical practice. Hence, there is a need for more elaborate studies of mediastinal lesions to make the pathologists and clinicians aware of the large spectrum of these lesions. The present study describes the histomorphological spectrum of various mediastinal lesions in a tertiary care hospital in India, along with the discussion of some unusual and interesting cases. Considering the limited diagnostic material obtained in guided biopsies, the adequacy of such tissue for providing a definite opinion was also evaluated. Methods: This was a retrospective study performed on 125 mediastinal masses diagnosed on surgically resected specimens as well as needle biopsies over a period of two years (January 2012-December 2013). A few cases had inadequate diagnostic material, making a total of 116 cases which were further evaluated. Results: A total of 116 patients of mediastinal lesions were included in the study. Most of the lesions were in 21-30 yr age group, with male:female ratio of 1.7:1. Anterior mediastinal compartment was most commonly involved. Majority of the cases (62.1%) were of neoplastic nature, with benign tumours (34.5%) being more common than malignant ones (27.6%). Thymoma followed by lymphoma constituted the most common mediastinal tumours. One-third of the total cases were diagnosed on needle biopsy samples. All cases where needle biopsy was followed by resection specimen showed concordant diagnosis. The percentage adequacy of biopsy was 91.7 per cent and the diagnostic accuracy was 100 per cent. Interpretation & conclusions: This study provides the histomorphological spectrum and biological diversity of the mediastinal lesions. It also emphasizes that biopsy is sufficiently adequate, with the help of a comprehensive immunohistochemistry panel, for providing a definite diagnosis in majority of cases.

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Penetrating Thoracic Trauma Patients with Gross Physiological Derangement: A Responsibility for the General Surgeon in the Absence of Trauma or Cardiothoracic Surgeon?

et al. 2016

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Most of the injuries in the chest can be managed by simple procedures to control life-threatening bleeding. The techniques required are similar to those taught to and are practiced comfortably by general surgeons used to work in the abdominal cavity. We encourage the general surgeon who receives a grossly unstable patient with penetrating thoracic trauma to operate, instead of adding risk to the patient's physiology by a transfer to cardio-thoracic or dedicated trauma units.

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Presentation of primary mediastinal masses in Ibadan

Cited by 9 publications

References 16 publications

Mediastinal Masses: Pathophysiological Issues and Management Challenges in a Developing World

Mediastinal Masses: Pathophysiological Issues and Management Challenges in a Developing World

Morphological spectrum of mediastinal lesions with special emphasis on evaluation of needle biopsy

Penetrating Thoracic Trauma Patients with Gross Physiological Derangement: A Responsibility for the General Surgeon in the Absence of Trauma or Cardiothoracic Surgeon?

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