Presentations and Outcomes of Thyroid Storm

Shahid, Muhammad; Kiran, Zareen; Sarfraz, Aqiba; Hasan, Syed Saud; Adnan, Syed Muhammad; Baloch, Akhtar

doi:10.29271/jcpsp.2020.03.330

Cited by 7 publications

(8 citation statements)

References 2 publications

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“…The descriptive statistics showed that the wife’s self-rated depression score was 1.03 points higher than that of the husband, and the score of marital satisfaction and neurotic personality were similar between the husband and wife. Consistent with the results of two studies conducted in Poland [ 42 ] and Pakistan [ 43 ], wives are more depressed and dissatisfied with marriage than husbands. The same research results were reported in a study by Peterson et al [ 44 ].…”

Section: Discussionsupporting

confidence: 88%

The effect of marital satisfaction on the self-assessed depression of husbands and wives: investigating the moderating effects of the number of children and neurotic personality

Liu

Yang

2023

BMC Psychol

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Background Based on the family system theory, there is an interactive relationship in the family, especially the cognitive style and emotional changes of the husband and wife will affect the behavior, cognition and emotion of the partner. Data about the effects of marital relationships on mental health are often paired. Scholars study the effect of individual independent variables on the dependent variables and the effect of spouse independent variables on the dependent variables to explore the actor and partner effect in marital relationships. Methods This study used the China Family Panel Studies (CFPS) 2018 dataset to collect paired data on the marital satisfaction and self-rated mental health of 9,560 couples. The Actor–Partner Interdependence Moderation Model (APIMoM) was used to analyze whether moderator variables affect the direction and strength of the effect of marital satisfaction on self-rated depression. In the robustness test part, the robustness of the APIMoM model was tested by reanalyzing the independent variables using two kinds of binary codes respectively, and the results showed that the models were robust. Results Individuals’ marital satisfaction was significantly negatively correlated with their own depression level and with that of their spouse. The number of family members had a positive moderating effect on the results of the wife’s partner effect. Couples who lived in the environment with more family members had lower depression scores. Couples who have more children have higher depression scores. The number of children has a negative moderating effect on the results of partner effect of husbands and wives. The wife’s neurotic personality score has a negative moderating effect on the wife’s actor effect. Conclusions In terms of measures to prevent depression, women’s mental health should be given more priority than men’s. Living in a larger family with more children is beneficial for couples’ mental health. Efforts to prevent depression in couples should take into account the neurotic character of the members, especially the wife, and design special treatment and preventive measures accordingly. These findings highlight that binary dynamics should be considered in exploring what factors influence the mental health of married couples.

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Section: Discussionsupporting

confidence: 88%

The effect of marital satisfaction on the self-assessed depression of husbands and wives: investigating the moderating effects of the number of children and neurotic personality

Liu

Yang

2023

BMC Psychol

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“…Multisystem dysfunction of the cardiovascular system, thermoregulatory system, gastrointestinal-hepatic system, and central nervous system are common, and the Burch-Wartofsky scoring system is often used to standardize the diagnosis [ 1 , 4 ]. Our patient’s presentation corresponded with the classic clinical presentation of thyroid storm [ 5 ], which includes altered mentation, hyperpyrexia, tachycardia, nausea, and vomiting. However, in the absence of a history of hyperthyroidism, sepsis was considered as the most likely cause, and further testing was only initiated after the workup for sepsis was negative.…”

Section: Discussionsupporting

confidence: 62%

Increased Ileostomy Output as an Indicator of Thyroid Storm in a Patient without an Established History of Underlying Thyroid Disease

et al. 2021

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Patient: Male, 27-year-old Final Diagnosis: Thyroid storm Symptoms: Abdominal pain • agitation • fever • high ileostomy output • tachycardia • tachypnea • weight loss Medication: — Clinical Procedure: — Specialty: Critical Care Medicine Objective: Unusual clinical course Background: Thyroid storm, also known as thyrotoxic crisis, is a rare but life-threatening endocrine emergency that presents with multisystem involvement. Patients present with pronounced signs of hyperthyroidism, fever, tachycardia, and differing severities of multisystem dysfunction and decompensation. Early recognition and prompt initiation of treatment are important. The development of thyroid storm in patients with no established history of underlying hyperthyroidism is rare. Case Report: In this case report, we describe the occurrence of thyroid storm in a 27-year-old man without an established history of underlying thyroid disease, who was admitted to the Intensive Care Unit (ICU) with a high ileostomy output and fever. Although initially treated for possible sepsis, the diagnosis of thyroid storm was made only after a thorough workup was initiated and he was found to have underlying Graves’ disease. Prompt treatment resulted in the resolution of symptoms and avoided potential morbidity and mortality. Conclusions: This case highlights the potential difficulty in diagnosing thyroid storm in a patient admitted to the ICU without an established history of hyperthyroidism. Upgrade in care, timely diagnosis, and initiation of appropriate therapy led to a favorable outcome. Clinicians should consider hyperthyroidism as a possible cause of high ileostomy output, especially when it does not resolve with traditional treatment and no obvious cause can be identified. This case demonstrates the challenges presented when the patient’s history and clinical signs are ambiguous and stresses the importance of “outside the box” thinking.

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“…Presently, diabetes mellitus has become a major health issue. By 2035, about 592 million people would be diabetic patients, which will be 210 million higher than reported in 2013 (Shahid et al, 2016). Every year, the number of people affected by this lifelong health problem is increasing.…”

Section: Introductionmentioning

confidence: 92%

Study of anti-diabetic, beta-carotene-bleaching inhibiting and iron chelating properties of Carissa opaca root extracts

Ahmed

Malik

Maqsood

et al. 2022

Braz. J. Pharm. Sci.

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Degenerative diseases diabetes and oxidative stress constitute a major health concern worldwide. Medicinal plants are expected to provide effective and affordable remedies. The present research explored antidiabetic and antioxidant potential of extracts of Carissa opaca roots. Methanolic extract (ME) was prepared through maceration. Its fractions were obtained, sequentially, in hexane, chloroform, ethyl acetate and n-butanol. An aqueous decoction (AD) of the finely ground roots was obtained by boiling in distilled water. The leftover biomass with methanol was boiled in water to obtain biomass aqueous decoction (BAD). The extracts and fractions showed considerable porcine pancreatic α-amylase inhibitory activity with IC 50 in the range of 5.38-7.12 mg/mL while acarbose had 0.31 mg/mL. The iron chelating activity in terms of EC 50 was 0.2939, 0.3429, 0.1876, and 0.1099 mg/mL for AD, BAD, ME, and EDTA, respectively. The EC 50 of beta-carotene bleaching activity for AD, BAD, ME, and standard BHA were 4.10, 4.71, 3.48, and 2.79 mg/mL, respectively. The total phenolic content (TPC) and total flavonoid content (TFC) of AD and BAD were also considerable. In general, ethyl acetate fraction proved to be the most potent. Thus, the C. opaca roots had excellent antioxidant activity while having moderate α-amylase inhibitory potential.

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Presentations and Outcomes of Thyroid Storm

Abstract: The aim of this study is to describe the characteristics and outcome of thyroid storm patients presenting at two tertiary care centres of Karachi, i.e.

Cited by 7 publications

References 2 publications

The effect of marital satisfaction on the self-assessed depression of husbands and wives: investigating the moderating effects of the number of children and neurotic personality

The effect of marital satisfaction on the self-assessed depression of husbands and wives: investigating the moderating effects of the number of children and neurotic personality

Increased Ileostomy Output as an Indicator of Thyroid Storm in a Patient without an Established History of Underlying Thyroid Disease

Study of anti-diabetic, beta-carotene-bleaching inhibiting and iron chelating properties of Carissa opaca root extracts

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