Presentations of patients of poisoning and predictors of poisoning-related fatality: Findings from a hospital-based prospective study

Lee, Hsin Ling; Lin, Hung Jung; Yeh, Steve T.; Hsien, Chih; Guo, How‐Ran

doi:10.1186/1471-2458-8-7

Cited by 66 publications

(90 citation statements)

References 43 publications

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“…W odniesieniu do postaci trucizny badanie wskazało głównie na płyny (związki fosforoorganiczne, pyretroidy) i proszki (fosforek glinu). Istotną rolę w diagnostyce odgrywają parametry życiowe, gdyż stanowią one główny komponent zespołów toksycznych [31,32]. Większość wcześniejszych badań koncentrowała się na relacji pomiędzy danym rodzajem trucizny a związanym z nią rokowaniem.…”

Section: Discussionunclassified

“…The liquid and powder type of poisons were mainly encountered in the study that comprised of aluminum phosphide in case of powder and Organophosphorus, pyrethroids in case of liquid poisons. Vital signs play an important role in diagnosis since they are the key components of toxic syndromes [31,32]. Most of the previous research focused on the relationship between a single specific poison and its prognostic factors.…”

Section: Discussionmentioning

confidence: 99%

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Prospects of poisoning – a multi facet study

Mishra¹,

Kulkarni²,

Sane³

et al. 2016

amsik

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StreszczenieCel pracy: Ustalenie profilu demograficznego, cech klinicznych oraz analiza trucizny w warunkach klinicznych. Badanie przeprowadzono w Sri Aurobindo Medical College oraz w PG Institute w Indore (stan Madhya Pradesh). Łącznie przeanalizowano 75 przypadków zatruć pod kątem danych demograficznych, parametrów życiowych (ciśnienie krwi, puls, tętno, źrenice itd.), cech klinicznych (np. wymioty, ślinienie, przytomność itd.), rodzaju trucizny oraz jej analizy. Wyniki: Zatrucia występowały częściej w grupie osób w wieku 15-25 lat, częściej u mężczyzn niż u kobiet oraz u wyznawców hinduizmu. Dochodziło do nich głównie na obszarach wiejskich oraz u osób żyjących w związkach mał-żeńskich. Większość pacjentów zwolniono do domu po przeprowadzeniu odpowiednich procedur terapeutycznych i udzieleniu porady, u większości stwierdzono zmienione parametry życiowe i cechy kliniczne. Ocenie poddano związ-ki fosforoorganiczne oraz fosforek glinu. Wnioski: Działania profilaktyczne należy realizować poprzez edukację, odpowiednie doradztwo, wspieranie ośrodków informacji o zatruciach i tworzenie oddziałów toksykologicznych w szpitalach.Słowa kluczowe: zatrucie, profil demograficzny, cechy kliniczne, analityczne. AbstractAim of the study is to find out demographic profile, clinical characteristics and analysis of poison in clinical set up. The study carried out in Sri Aurobindo Medical College and PG Institute Indore, Madhya Pradesh. Total 75 cases of poisoning were studied for demographic profile, vitals (BP, pulse, heart rate, pupils, etc.), clinical features (such as vomiting, salivation, consciousness, etc.), type of poison and its analysis. Results: Poisoning was more common in cases between 15 and 25 years of age, in males than in females and in Hindu religion. Poisoning cases were predominantly from rural areas and in married people. Majority of cases were discharged after proper treatment and counseling. Altered vitals and clinical features were found in most of the cases. Organophosphate and aluminum phosphide compound were evaluated in most of the cases. Conclusions: Preventive measures should be applied through educating people, proper counseling, promoting poison information centers, and introducing separate toxicological units in hospitals. WstępOstre zatrucia różnego rodzaju substancjami uznaje się za nagłe przypadki medyczne stanowiące poważny problem w kontekście zdrowia publicznego i są istotnym obciążeniem dla służby zdrowia [1,2]. W przypadku stwierdzenia obecności substancji chemicznych pochodzenia zewnętrznego w próbkach materiałów biologicznych (treść żołądkowa, krew, mocz) pozyskiwanych w toku postępowań sądowo--lekarskich konieczne jest przeprowadzenie odpowiednich badań toksykologicznych [3]. Trucizna to substancja powodująca zniszczenie lub uszkodzenie organizmu, a kontakt z nią (poprzez dotyk, połknięcie lub wdychanie) zagraża życiu poszkodowanego [4].W poszczególnych częściach świata występują róż-ne rodzaje trucizn, na co wpływają czynniki społecz-noekonomiczne oraz zróżnicowanie kulturowe [5]. W ...

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Section: Discussionunclassified

Section: Discussionmentioning

confidence: 99%

Prospects of poisoning – a multi facet study

Mishra¹,

Kulkarni²,

Sane³

et al. 2016

amsik

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“…7,8,16 In the above-mentioned study by Chien et al, mortality among men was 2.3 fold higher than women. In that study, when reason for poisoning was considered in relation to gender, it was seen that mortality rate due to unintentional poisoning was higher in men compared to women, whereas mortality related to intentional poisoning was higher in women compared to men.…”

Section: Discussionmentioning

confidence: 99%

“…Thus, it is rather essential to identify regional epidemiological data for the prevention of poisoning and more realistic use of sources. 7,12 Coşkun ve ark. In a study by Seydaoglu et al performed on 2229 patients presented with poisoning to emergency department, women (mean age 24 years) were significantly younger than men (mean age 29 years).…”

Section: Discussionmentioning

confidence: 99%

“…6 Previous studies suggested that age, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, Glasgow coma score (GCS) at admission, type of the agent, reason for poisoning, respiratory failure, renal failure, hypotension, cardiac rhythm abnormalities and abnormal body temperature might be predictors of mortality in patients admitted to intensive care unit (ICU). 7,8 In our country, intensive care mortality related to poisoning was found to vary between 0.21 and 15.7%. However, these studies have usually focused on etiological agents and mortality of poisoning, and there are limited number of studies on factors which influence mortality and morbidity.…”

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Predictors of Mortality in Critically Ill Patients with Poisoning: A Single Center Experience

Coşkun¹,

Gündoğan²,

Atağ³

et al. 2013

Turkiye Klinikleri J Med Sci

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A AB BS ST TR RA AC CT T O Ob bj je ec ct ti iv ve e: : Poisoning is among the common health care problems which may be fatal and 3-5% of the acutely poisoned patients need intensive care admission. The aim of this study was to examine the acutely poisoned patients admitted to intensive care unit (ICU) in terms of individual, etiological and demographical characteristics and also to determine the factors affecting mortality. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : This study was retrospectively conducted on the patients admitted to medical ICU of a university hospital due to acute poisoning over a six year period. The patients' age, gender, comorbid disease status, sociocultural characteristics, cause of the poisoning, transfer time to hospital and to the ICU, signs and symptoms, laboratory data, Glasgow coma score, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, Sequential Organ Failure Assessment score, length of stay in ICU, the treatments employed and their results were analyzed. R Re es su ul lt ts s: : The total number of the patients included in the study was 190. The median age of the patients was 28.5 (16-72) years and 97 (51%) patients were females. The mean length of stay in ICU was 4.2±3.6 days. The overall mortality rate was 8.4%. Independent risk factors for mortality were presence of concomitant physical disorders, time to ICU admission, and higher APACHE II scores. C Co on nc cl lu us si io on n: : Individual characteristics, cause of poisoning and type of toxic agent should be clearly determined since they are predictors for mortality. Early intervention is life saving. ICU scoring systems in predicting mortality are very valuable and should be used. K Ke ey y W Wo or rd ds s: : Intensive care; mortality; poisoning Ö ÖZ ZE ET T A Am ma aç ç: : Zehirlenme ölümcül olabilen ve akut zehirlenmiş hastaların %3-5'inin yoğun bakıma yatışını gerekebilen yaygın bir sağlık problemidir. Bu çalışmanın amacı mortaliteyi etkileyen faktörleri belirlemek amacıyla yoğun bakım ünitesine (YBÜ) kabul edilen akut zehirlenmiş hastaların bireysel, etyolojik ve demografik özelliklerini incelemektir. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Bu çal-ışma retrospektif olarak altı yıl içinde akut zehirlenme nedeniyle bir üniversite hastanesi medikal yoğun bakımına yatan hastalar üzerinde yapıldı. Hastaların yaş, cinsiyet, eşlik eden hastalık durumu ve sosyokültürel özellikleri, zehirlenme nedeni, hastane ve yoğun bakıma transfer süresi, belirti ve bulguları, laboratuvar verileri, Glasgow koma skoru, Akut Fizyoloji ve Kronik Sağlık Değerlendirmesi II (APACHE II) skoru, Ardışık Organ Yetersizliğinin Değerlendirilmesi skoru, YBÜ yatış süresi, tedavileri ve sonuçları analiz edildi. B Bu ul lg gu ul la ar r: : Çalışmaya dahil edilen hastaların toplam sayısı 190 idi. Hastaların ortanca yaşı 28,5 (16-72) yıldı ve 97 (%51) hasta kadın idi. Yoğun bakımda kalış süresi ortalama 4,2±3,6 gün idi. Mortalite oranı % 8,4 idi. Mortalite için bağımsız risk faktörleri fiziksel alt hastalığı...

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