“…2,4,9 Although HiB has not been completely eradicated, studies have shown a shift in microbiological trends of acute pediatric infections related to epiglottitis, meningitis, rhinosinusitis, periorbital infections, and otitis media. [12][13][14][15][16] The heptavalent pneumococcal conjugate vaccine (Prevnar or PCV-7) was introduced in 2000 for children younger than 24 months. Many authors have studied the effects of the vaccine on common pediatric diseases.…”