“…The authors believe the sample size was not sufficiently powered to detect differences between the groups concerning pain, need for pain medication, and peri-implant mucosa status, since some authorities have reported that HPLs have antiseptic properties related to the avoidance of postoperative secondary infections and a bio-modulating potential for healing improvement (Al-Delayme, 2019;Fornaini et al, 2015). Research, Society andDevelopment, v. 9, n. 7, e128974122, 2020 (CC BY 4.0) | ISSN 2525-3409 | DOI: http://dx.doi.org/10.33448/rsd-v9i7.4122 Besides the high price and specific operator training (Ibidem, 2015), HPL techniques have been thought to have some possible clinical disadvantages such as the need for sufficient adjacent keratinized tissues around the implant (Kaur et al, 2018) and previous knowledge of the implant localization (El-Kholey, 2014), direct damages to the implant surface topography (Bajaj et al, 2020), and bone overheating (Ibid, 2019).…”