Preservation of Medicines and Cosmetics

Hiom, Sarah

doi:10.1002/9781118425831.ch17

Cited by 2 publications

(2 citation statements)

References 90 publications

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“…). These days, to ensure microbiological quality, consumer safety and the organoleptic properties of cosmetic products, manufacturers need to comply with defined standards (BIO ECOCERT, COSMOS) (Hiom ). As a result, cosmetic production requires disinfection steps in the production chain before and during the manufacture/conditioning stages.…”

Section: Introductionmentioning

confidence: 99%

Enterobacter gergoviae membrane modifications are involved in the adaptive response to preservatives used in cosmetic industry

2014

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Section: Introductionmentioning

confidence: 99%

Enterobacter gergoviae membrane modifications are involved in the adaptive response to preservatives used in cosmetic industry

2014

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“…The choice of these substances depends on their aspect, their toxic effect, and also the nature of the cosmetics [ 30 , 32 , 42 , 54 , 55 ]. Water activity can also be reduced by the use of vapour-resistant bottles, film strip, vapour-repellent film coatings, or polyacrylamide hydrogels [ 56 ]. Berthele et al [ 57 ] reported that a water activity value of 0.8, and without preservatives incorporated in the formulas tested, can guarantee microbiological stability of the cosmetic products.…”

Section: Preservation Strategiesmentioning

confidence: 99%

Cosmetics Preservation: A Review on Present Strategies

et al. 2018

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Cosmetics, like any product containing water and organic/inorganic compounds, require preservation against microbial contamination to guarantee consumer’s safety and to increase their shelf-life. The microbiological safety has as main goal of consumer protection against potentially pathogenic microorganisms, together with the product’s preservation resulting from biological and physicochemical deterioration. This is ensured by chemical, physical, or physicochemical strategies. The most common strategy is based on the application of antimicrobial agents, either by using synthetic or natural compounds, or even multifunctional ingredients. Current validation of a preservation system follow the application of good manufacturing practices (GMPs), the control of the raw material, and the verification of the preservative effect by suitable methodologies, including the challenge test. Among the preservatives described in the positive lists of regulations, there are parabens, isothiasolinone, organic acids, formaldehyde releasers, triclosan, and chlorhexidine. These chemical agents have different mechanisms of antimicrobial action, depending on their chemical structure and functional group’s reactivity. Preservatives act on several cell targets; however, they might present toxic effects to the consumer. Indeed, their use at high concentrations is more effective from the preservation viewpoint being, however, toxic for the consumer, whereas at low concentrations microbial resistance can develop.

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Preservation of Medicines and Cosmetics

Cited by 2 publications

References 90 publications

Enterobacter gergoviae membrane modifications are involved in the adaptive response to preservatives used in cosmetic industry

Enterobacter gergoviae membrane modifications are involved in the adaptive response to preservatives used in cosmetic industry

Cosmetics Preservation: A Review on Present Strategies

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