“…Enduring factors, including the ageing of the population and the spread of chronic diseases, particularly diabetes and obesity, have contributed to the global escalation in the occurrence rates of chronic wounds; it also appears that the breakout of the coronavirus 2019 disease has increased the prevalence of chronic wounds (likely as a result of less effective preventative care and shift of health resources to fight the pandemic, as well as because prone patient positioning, causing anterior PUs, became more common). 6 , 7 , 8 , 9 , 10 , 11 , 12 Overall, hard‐to‐heal wounds are typically associated with considerable suffering, loss of quality of life for patients and family members and, sometimes, with severe and chronic pain, risk of infections, osteomyelitis, sepsis and the development of multiple organ failure leading to death. 1 , 13 For example, the 5 year mortality rate for people with DFUs and associated (minor/major amputation) complications is comparable to those of common cancers (e.g., breast or lung).…”