Pressure pulsation in roller pumps: A validated lumped parameter model

Moscato, Francesco; Colacino, Francesco Maria; Arabia, M.; Danieli, Guido

doi:10.1016/j.medengphy.2008.02.007

Cited by 12 publications

(13 citation statements)

References 17 publications

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“…In a closed system, the input and output pressure for the peristaltic pump is a complex function of the type and mechanism of pumping. 20 We added a second pulse dampener at the output side of the parallel-plate flow chamber and the input side of the pump. The addition of the second pulse dampener dramatically decreased the mean flow variation (Figure 2).…”

Section: Resultsmentioning

confidence: 99%

A multichannel dampened flow system for studies on shear stress-mediated mechanotransduction

2012

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Shear stresses are powerful regulators of cellular function and potent mediators of the development of vascular disease. We have designed and optimized a system allowing the application of flow to cultured cells in a multichannel format. By using a multichannel peristaltic pump, flow can be driven continuously in the system for long-term studies in multiple isolated flow loops. A key component of the system is a dual-chamber pulse dampener that removes the pulsatility of the flow without the need for having an open system or elevated reservoir. We optimized the design parameters of the pulse dampening chambers for the maximum reduction in flow pulsation while minimizing the fluid needed for each isolated flow channel. Human umbilical vein endothelial cells (HUVECs) were exposed to steady and pulsatile shear stress using the system. We found that cells under steady flow had a marked increased production of eNOS and formation of actin stress fibers in comparison to those under pulsatile flow conditions. Overall, the results confirm the utility of the device as a practical means to apply shear stress to cultured cells in the multichannel format and provide steady, long term flow to microfluidic devices.

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Section: Resultsmentioning

confidence: 99%

A multichannel dampened flow system for studies on shear stress-mediated mechanotransduction

2012

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“…Regarding computational or experimental tools, many researchers have attempted to shed light on the issue of non-pulsating roller pumping. Using a simple lumped parameter mathematical model of a roller pump, Moscato [15] simulated the pump dynamically in order to clarify the uncontrolled pulsation mechanism. The tube compression/release mechanism actuated by the rollers during their engaging and disengaging phases causes the triggering oscillations validated by experimental measurements.…”

Section: Introductionmentioning

confidence: 99%

Optimal Design in Roller Pump System Applications for Linear Infusion

et al. 2020

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In this study, an infusion roller pump comprising two separate innovative resilient tube designs is presented. The first incorporates the flexible tubing cross-section area in its relaxed state as a lenticular one for power reduction reasons. The second keeps the previous lenticular cross-section along its length, while it additionally incorporates an inflating portion, for creating a momentary flow positive pulse to balance the void generated by the roller disengagement. Fluid–Structure Interaction (FSI) simulations cannot provide quantitatively realistic results, due to the limitation of full compression of the tube, and are only used qualitatively to reveal by which way to set the inflated portion along the tube length in order to suppress backflow and achieve constant flow rate. Finally, indirect lumen volume measurements were performed numerically and an optimum design was found testing eight design approaches. These indirect fluid volume measurements assess the optimum inflated tube’s portion leading to backflow and pulsating elimination. The optimum design has an inflation portion of 75 degrees covering almost 42% of the curved part of the tube, while it has a constant zone with the maximum value of inflated lenticular cross-section, within the portion, of 55 degrees covering about 73% of the inflation portion.

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“…These modelling techniques are not effective when modelling larger flow rates, yet remain useful in detecting unique attributes of viscous flow in roller pumps, such as trapping [11]. More recently, Moscato et al [12] provided a paper on a validated lumped parameter model which is indicated to be accurate with larger flow rates. Instead of assuming an infinite wave-train, the model has an individual flow rate pulsation as an input for each roller coming into or out of contact with the process tube.…”

Section: Introductionmentioning

confidence: 99%

“…The lumped parameter model provided in [12] is, however, developed for a two-roller pump. As roller pumps can be configured to have varying numbers of rollers, the need for a generalised model exits.…”

Section: Introductionmentioning

confidence: 99%

“…This paper provides a first principles modelling approach for peristaltic pumps with varying numbers of rollers. An alternative model to that provided in [12] is discussed in depth with regards to both the modelled flow rate and lumped parameter model. The alternative approach allows for roller pumps to be modelled with varying numbers of rollers by changing the frequency of the controlled sources, rather than changing the model itself.…”

Section: Introductionmentioning

confidence: 99%

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Modelling the pulsatile flow rate and pressure response of a roller-type peristaltic pump

McIntyre¹,

Schoor²,

Uren³

et al. 2020

Preprint

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The unique working mechanics of roller-type peristaltic pumps have allowed their applications to span a wide variety of sectors and industries. The roller-type pump's accurate dosing and hydrostatic capabilities can theoretically allow for the pump to be used for hydraulic actuation (as an electro-hydrostatic actuator) for low pressure applications. This however requires accurate control of the peristaltic pump and its flow rate. The associated pressure pulsations will also have an impact on the pump's selection criteria. Accurate control of roller-type peristaltic pumps commonly rely on flow-meters, which increases the cost of the pump and can complicate control strategies. Current modelling approaches either do not rely on first principle modelling and require expensive simulation software, or do not apply for larger Reynolds numbers at larger flow rates. The most applicable model focusses on the flow rate for each roller individually. This implies that the model requires alterations in order to accommodate pumps with varying numbers of rollers. This paper presents an alternative modelling methodology towards the volume flow rate, pulsatile flow rate qualities, and pressure pulsations commonly found on peristaltic pumps. The model instead focusses on the flow rate at the inlet and the outlet of the pump, rather than on each individual roller. This model is highly scalable and allows for varying number of rollers. The model is validated using a 3D printed peristaltic pump and pulsatile flow rate test bench. The pump is capable of accommodating roller housings with varying numbers of rollers (3 or 2) in order to validate the model.

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Pressure pulsation in roller pumps: A validated lumped parameter model

Cited by 12 publications

References 17 publications

A multichannel dampened flow system for studies on shear stress-mediated mechanotransduction

A multichannel dampened flow system for studies on shear stress-mediated mechanotransduction

Optimal Design in Roller Pump System Applications for Linear Infusion

Modelling the pulsatile flow rate and pressure response of a roller-type peristaltic pump

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