Pressurized Organic Solvent Extraction with On-line Particle Formation by Supercritical Anti Solvent Processes

Abstract

In this work, anovel on-line process for pressurised hot organic solvent extraction of antio xidants from plantsas well as precip itation of the extract with or without a carrier material in one step was developed. This process has been called OEPO,Organic solvent Ext raction and On-line particle formation. With this process, different products with a very low residual organic solvent concentration (< 50 ppm) can be obtained by the use of supercritical CO 2 as anti solvent for solvent elimination.OEPO process consists of hyphenated Pressurized Liquid Extraction (PLE)-Supercritical Anti So lvent (SAS) precipitation, PLE-SAS co-p recipitat ion and PLE-Supercritical Fluid Ext raction of Emulsions (SFEE). OEPO process was successfully developed using Brazilian g inseng roots (Pfa ffiaglomerata)as a model case using ethyl acetate as extracting solvent. Results were co mpared, in terms of antio xidant activity o r mo rphology, with the ones obtained by each process separately.In addition, an optimizat ion study for antio xidants recovery was performed using ethyl acetate as extracting solvent during PLE process. Optimu m PLE extracts were produced under moderate extraction temperature (373 K) and high static extraction t ime (15 min). Under this condition an ext raction yield o f 1% (d ry basis, d.b.) and an antioxidant activity of 53% are obtained, wh ich was appro ximately 14% higherthan that observed after PLE-SAS p recipitation and after SAS precipitation performed in two steps (step one -PLE ext raction; step two -SAS precipitation by the use of the ext ract solution produced by step one stored).Similar behavior (hyphenated process producing similar p roducts than the two step process done separately) was observed for PLE-SAS co-precip itation and PLE-SFEE indicating that the OEPO process developed in this work can be considered as a suitable and p ro mising process to obtain, in only one step, different products (precipitated extract, co-precipitated extract or encapsulated extract in suspension), direct ly fro m plant materials.

Obtaining annatto seed oil miniemulsions by ultrasonication using aqueous extract from Brazilian ginseng roots as a biosurfactant

“…The extraction was performed until the solvent mass-to-feed mass ratio (S/F) was 3.5, with a constant flow rate of 100 g min À1 . BGR saponins were obtained from Brazilian ginseng (P. glomerata) plants cultivated in the experimental field of CPQBA (Campinas, Brazil) and were collected on November 17, 2008, after 7 years of cultivation and processed in our own lab as described elsewhere (Santos et al, 2012). The saponin-rich extract was obtained by using a pressurized liquid extraction system as described by Debien and Meireles (2014).…”

Study of an Extraction Process as the Pretreatment Step for Sugar Production from Acid Hydrolysis

“…Species of the Pfaffia genus, such as Pfaffia glomerata, belong to the Amaranthaceae family and are Brazilian substitutes for plants of the Panax genus; these species are popularly called Brazilian ginseng [26][27][28][29]. Brazilian ginseng roots (BGR) are used in herbal medicine and as a dietary supplement due to anti-inflammatory and analgesic properties [27], as well as cellular stress and immunological effects [28,30].…”

Sub- and supercritical fluid technology applied to food waste processing

“…Santos et al [132] proposed a new technique to concentrate valuable compounds from plants, integrating pressurized solvent extraction to the precipitation of the extract, with or without a coating material. With this process, different products with very low concentrations of residual organic solvents (<50 ppm) could be obtained, using supercritical CO 2 as antisolvent, to eliminate the solvent.…”