PRESTO-SENSE: An ultrafast whole-brain fMRI technique

Golay, Xavier; Pruessmann, Klaas P.; Weiger, Markus; Crelier, Gérard; Folkers, Paul J. M.; Kollias, Spyros; Boesiger, Peter

doi:10.1002/1522-2594(200006)43:6<779::aid-mrm1>3.0.co;2-4

Cited by 108 publications

(79 citation statements)

References 27 publications

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“…Resting-state fMRI and DTI data were acquired on a 3 tesla Philips Achieva Medical Scanner (Philips Medical Systems) at the University Medical Center Utrecht, The Netherlands. During the rest experiment, resting-state blood oxygenation level-dependent (BOLD) signals were recorded during a period of 8 min using a fast fMRI sequence [three-dimensional (3D) PRESTOSENSE p/s-reduction 2/2 (Golay et al, 2000;Neggers et al, 2008); repetition time (TR)/echo time (TE), 22 ms/32 ms using shifted echo; flip angle, 9°; dynamic scan time, 0.5 s; 1000 timeframes; field of view (FOV), 256 ϫ 256 mm; 4 mm isotropic voxel size; 32 slice volume covering the whole brain]. Directly after the fMRI time series, an additional functional scan was acquired with identical parameters but with a high anatomical contrast attributable to an increased flip angle of 25°.…”

Section: Methodsmentioning

confidence: 99%

Microstructural Organization of the Cingulum Tract and the Level of Default Mode Functional Connectivity

et al. 2008

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The default mode network is a functionally connected network of brain regions that show highly synchronized intrinsic neuronal activation during rest. However, less is known about the structural connections of this network, which could play an important role in the observed functional connectivity patterns. In this study, we examined the microstructural organization of the cingulum tract in relation to the level of resting-state default mode functional synchronization. Resting-state functional magnetic resonance imaging and diffusion tensor imaging data of 45 healthy subjects were acquired on a 3 tesla scanner. Both structural and functional connectivity of the default mode network were examined. In all subjects, the cingulum tract was identified from the total collection of reconstructed tracts to interconnect the precuneus/posterior cingulate cortex and medial frontal cortex, key regions of the default mode network. A significant positive correlation was found between the average fractional anisotropy value of the cingulum tract and the level of functional connectivity between the precuneus/posterior cingulate cortex and medial frontal cortex. Our results suggest a direct relationship between the structural and functional connectivity measures of the default mode network and contribute to the understanding of default mode network connectivity.

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Section: Methodsmentioning

confidence: 99%

Microstructural Organization of the Cingulum Tract and the Level of Default Mode Functional Connectivity

et al. 2008

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“…However, SSFP contrast is challenging at high field because of its high SAR from RF excitation. Second, we may use an echo-shifting technique to reduce the TR (Golay et al, 2000;Liu et al, 1993), as demonstrated in our previous 2D InI study (Lin et al, 2006). Both alternatives are capable of reducing the sampling time to around 20 ms.…”

Section: Future Developmentmentioning

confidence: 99%

“…Prior information can be incorporated by combining EPI with parallel MR imaging (Golay et al, 2000;Preibisch et al, 2003;Schmidt et al, 2005;Weiger et al, 2002), resulting in fMRI detection sensitivity improvements with sensitivity encoded parallel MRI techniques (Lin et al, 2005b). Prior-informed parallel MRI has been explored using a fixed regularization parameter with empirical singular value decomposition truncation (King, 2001;Sodickson, 2000).…”

Section: Introductionmentioning

confidence: 99%

Event-related single-shot volumetric functional magnetic resonance inverse imaging of visual processing

et al. 2008

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Developments in multi-channel radio-frequency (RF) coil array technology have enabled functional magnetic resonance imaging (fMRI) with higher degrees of spatial and temporal resolution. While modest improvement in temporal acceleration has been achieved by increasing the number of RF coils, in parallel data acquisition techniques, the maximum attainable acceleration is intrinsically limited only by the amount of independent spatial information in the combined array channels. Since the geometric configuration of a large-n MRI head coil array is similar to that used in EEG electrode or MEG SQUID sensor arrays, the source localization algorithms used in MEG or EEG source imaging can be extended to also process MRI coil array data, resulting in greatly improved temporal resolution by minimizing k-space traversal during signal acquisition. Using a novel approach, we acquire multi-channel MRI head coil array data and then apply inverse reconstruction methods to obtain volumetric fMRI estimates of blood oxygenation level dependent (BOLD) contrast at unprecedented whole-brain acquisition rates of 100 ms per sample. We call this combination of techniques magnetic resonance Inverse Imaging (InI), a method that provides estimates of dynamic spatially-resolved signal change that can be used to construct statistical maps of task-related brain activity. We demonstrate the sensitivity and inter-subject reliability of volumetric InI using an eventrelated design to probe the hemodynamic signal modulations in primary visual cortex. Robust results from both single subject and group analyses demonstrate the sensitivity and feasibility of using volumetric InI in high temporal resolution investigations of human brain function.

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“…Weiger et al (12) reported that in a clinical application, the performance of 3D contrast-enhanced MR angiography could be considerably improved with SENSE, enabling enhanced spatial and/or temporal resolution. SENSE is also used in real-time cardiac imaging (13) and brain functional MRI (fMRI) (14). However, no SENSE study has been reported regarding MRI of the liver, especially as concerns dynamic imaging.…”

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confidence: 99%

Double arterial phase dynamic MRI with sensitivity encoding (SENSE) for hypervascular hepatocellular carcinomas

Yoshioka

Takahashi

Yamaguchi

et al. 2002

Magnetic Resonance Imaging

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Purpose:To investigate the efficacy of SENSE MRI, including the double arterial phase dynamic study, to detect hypervascular hepatocellular carcinomas (HCCs). Materials and Methods:MRI of the liver was performed in 40 consecutive patients (20 by conventional MRI and 20 by SENSE MRI). The SENSE technique was used to obtain breath-hold T1-weighted FSE images (TR/TE ϭ 556/12 msec), respiratory-triggered T2-weighted FSE images (TR/ TE ϭ 1800/90 msec) with and without fat suppression, and dynamic MR images (TR/TE/FA ϭ 160 -168/4.6 msec/70°). In each arterial dominant phase and portal dominant phase, two scans were consecutively performed with one breathhold, leading to the double arterial phase and double portal phase images with SENSE. Results:The sensitivity of SENSE MRI for HCCs diagnosed from all MR images, including dynamic study, T1-weighted images, and T2-weighted images, was 91.7%, while that of conventional MRI was 76.3%. The positive predictive value of SENSE MRI for HCCs was 91.7%, while that of conventional MRI was 87.9%. In terms of HCCs Յ 10 mm, the sensitivity and positive predictive values of SENSE MRI were 78.6% and 78.6%, respectively, while those of conventional MRI were 27.3% and 60.0%, respectively. The number of detected HCCs Յ 10 mm was significantly larger in SENSE MRI than in conventional MRI (P Ͻ 0.05). The cause of false-positive lesions on SENSE MR images was an arterioportal shunt.Conclusion: SENSE MRI with double arterial phase dynamic study showed higher sensitivity compared to the conventional technique. Therefore, SENSE MRI is a promising method for the detection of HCC.

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PRESTO-SENSE: An ultrafast whole-brain fMRI technique

Cited by 108 publications

References 27 publications

Microstructural Organization of the Cingulum Tract and the Level of Default Mode Functional Connectivity

Microstructural Organization of the Cingulum Tract and the Level of Default Mode Functional Connectivity

Event-related single-shot volumetric functional magnetic resonance inverse imaging of visual processing

Double arterial phase dynamic MRI with sensitivity encoding (SENSE) for hypervascular hepatocellular carcinomas

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