Presumed Sterile Eosinophilic and Granulomatous Mural Folliculitis and Furunculosis in an Angora and Pygmy Crossbreed Goat

Abstract

Presumed sterile eosinophilic and granulomatous mural folliculitis and furunculosis was diagnosed in a goat. Dermatological findings included widespread, nonpruritic, bilaterally symmetrical exudation, crusting, alopecia, and thickened skin. Infectious causes were ruled out by negative histochemical stains and negative PCR for ovine herpesvirus-2 conducted on skin-biopsy specimens. There was a 50% reduction in the severity of the dermatitis with intramuscular injections of dexamethasone. A cause for the skin condition was not determined.

Granulomatous mural folliculitis in 16 domestic goats: Infection with malignant catarrhal fever viruses and colocalization with ovine herpesvirus-2 using in situ hybridization

“…However, the histologic features are consistent with other published reports of MCFV-induced GMF, and all other known differential diagnoses, other than the originally published diagnosis of presumed sterile eosinophilic and GMF and furunculosis, have been excluded. 37 GMF has not been previously reported in an MCFV-infected reservoir host, as goats are suggested as being for CpHV-3. Whether or not this is the case, classic vasculocentric MCF has been occasionally reported in reservoir hosts, e.g., OvHV-2 in sheep.…”

“…However, after 1 month the dexamethasone dose was reduced and there was onset of hindlimb paresis and recrudescence of skin lesions, necessitating euthanasia. 37 Of the three goats reported to have partial resolution of skin lesions, specific information regarding how the condition had improved was only available for goat 15. This goat was said to have a reduced severity of lesions, with only mild scaling, crusting, and alopecia multifocally across its body.…”