Objective. To conceptualize and measure community contextual influences on population health and health disparities. Data Sources. We use traditional and nontraditional secondary sources of data comprising a comprehensive array of community characteristics. Study Design. Using a consultative process, we identify 12 overarching dimensions of contextual characteristics that may affect community health, as well as specific subcomponents relating to each dimension. Data Collection. An extensive geocoded library of data indicators relating to each dimension and subcomponent for metropolitan areas in the United States is assembled. Principal Findings. We describe the development of community contextual health profiles, present the rationale supporting each of the profile dimensions, and provide examples of relevant data sources. Conclusions. Our conceptual framework for community contextual characteristics, including a specified set of dimensions and components, can provide practical ways to monitor health-related aspects of the economic, social, and physical environments in which people live. We suggest several guiding principles useful for understanding how aspects of contextual characteristics can affect health and health disparities.Key Words. Health disparity, residence characteristics, contextual data, population health, socioeconomic factors Much has been accomplished to improve health and reduce disparities through understanding and intervening on individual-level risk factors for major causes of morbidity and mortality (U.S. Preventive Services Task Force 1996; Ketola, Sipila, and Makela 2000). However, far less attention has been paid to understanding the effect of community contextual characteristics on health outcomes and disparities. Although research interest in the role of socioenvironmental factors in the etiology of disease has surged over the past decade (for reviews see Pickett and Pearl 2001;Macintyre, Ellaway, and Cummins 2002;Yen and Syme 1999), a recurrent theme in this literature is the need for greater attention to the conceptualization and empirical assessment of 1645 ways in which contextual characteristics of places impact health (Pickett and Pearl 2001;Macintyre, Ellaway, and Cummins 2002;Lynch 1997, 2001;Yen and Syme 1999;Diez-Roux 1998). In addition, there has been great academic and policy interest in implementing interventions aimed at improving socioenvironmental factors that could produce wide-ranging health benefits (for example see articles in the April 2003 supplement to the American Journal of Preventive Medicine on this topic). Many in public health believe these represent a promising approach to reducing the marked health disparities that remain a high-priority public health concern (U.S. Department of Health and Human Services 2000). Furthermore, this approach provides critical data to ensure that decisions regarding the provision of health care services do not occur in a vacuum, but instead are integrated into the larger picture of health-promoting and health-endangering char...