Pretreatment evaluation of adnexal tumors predicting ovarian cancer

Kobal, Borut; Rakar, S; Ribič-Pucelj, Martina; Tomaževič, Tomaž; Zaletel-Kragelj, Lijana

doi:10.1046/j.1525-1438.1999.99057.x

Cited by 4 publications

(2 citation statements)

References 19 publications

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“…20 Similarly, Kobal B et al reported 31.8% of benign lesions and 62.5% malignant lesions were multilocular. 23 Thus the present study and other studies mentioned above suggest that the malignant lesions are predominantly multilocular. The gray scale morphology in our sample size revealed that 71.4% of the benign tumors were cystic.…”

Section: Gray Scale Ultrasoundsupporting

confidence: 77%

Preoperative evaluation of ovarian masses with color Doppler and its correlation with pathological finding

Khurana

Satia

2016

Int J Reprod Contracept Obstet Gynecol

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Background: Most ovarian cancers are diagnosed in advanced stages because these tumours may not cause any specific symptoms, particularly in its early stages. Though specific risk actors have been identified there are no reliable screening tests for ovarian cancer. However, improvements in identification of women at high risk for ovarian cancer, as well as improved imaging techniques like the USG and color Doppler along with CT Scan and MRI has increased the likelihood of early detection. Methods:The aim of the study was to evaluate the efficacy of color and spectral Doppler in diagnosing the ovarian malignancy. A Prospective randomised study was conducted at a tertiary care centre where 50 patients with ovarian masses were selected. The study design included thorough history taking and clinical examination followed by evaluation of tumour markers. USG along with color Doppler evaluation was done followed by surgery and then corelated with histopathology. The color Doppler parameters such as vascularity, distribution of vascularity, pulsatility and resistive index were also evaluated and statistical significance assessed. Results: Color Doppler showed increased vascularity in 100% of malignant tumors in contrast to only 54.24% of benign tumors. Absent blood flow in a solid tumor almost always ruled out the possibility of malignancy. Spectral Doppler helped to assess the nature of the blood vessels picked up on color Doppler. All the patients in the malignant group and 4 patients in the borderline group had PI<1.0. Remaining 6 tumors with P1 <1.0 belonged to the benign group. Out of 15 patients with PI >1.0, 13 were benign and 2 patients had borderline tumours. RI of <0.4 was seen in 8 Patients with malignancy and RI of >0.4 was seen in 26 patients with benign lesions. Conclusions: Color Doppler is a good non-invasive modality to differentiate benign from malignant lesions. Vascularity is most sensitive and RI is most specific. Thus, color Doppler and spectral Doppler tremendously increased the reliability in diagnosing a malignant ovarian tumor. Color Doppler served as an important tool to rule out malignancy in solid tumors if they failed to show any intra-tumoral vascularity. B-Mode USG in combination with color Doppler and spectral Doppler is proposed as the first and foremost diagnostic modality in patients with ovarian tumor, so as to establish the definite diagnosis of malignancy early in the course of the disease.

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Section: Gray Scale Ultrasoundsupporting

confidence: 77%

Preoperative evaluation of ovarian masses with color Doppler and its correlation with pathological finding

Khurana

Satia

2016

Int J Reprod Contracept Obstet Gynecol

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“…43.5% cases of malignant tumors had ascites, whereas 5.71% benign tumours of mucinous cystadenomas had ascites. Prior studies have similarly found that papillary projections and ascites are indicative of malignancy [ 16 ]. Others have also noted that 41% cases of stage IV epithelial ovarian cancer have papillary projections [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

Validity of ultrasound with color Doppler to differentiate between benign and malignant ovarian tumours

Mahale,

Kumar,

Mahale

et al. 2024

Obstet Gynecol Sci

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Objective To assess the utility of ultrasound and color Doppler and the Accuracy of International Ovarian Tumor Analysis (IOTA) group classification in the preoperative evaluation of ovarian neoplasms to assess benign or malignant histopathology in the diagnosis of ovarian tumors.Methods This observational longitudinal prospective analysis of 60 patients was performed over a period of 2 years (2017- 2019). The mean age of the patients was 43.75 years. Ultrasonography of ovarian masses were evaluated, and cancer antigen-125 (CA-125) levels were evaluated. Based on the IOTA classification, the B and M features of adnexal masses were studied. Color Doppler imaging was performed to evaluate the patterns of vascularity and indices.Results Sixty patients with 35 benign, 23 malignant, and two borderline lesions were included in the study. In malignant lesions, 17 women (73.9%) were above the age of 45. The CA-125 cut off was ≥35 internatioal units/mL. Based on the IOTA classification, 27/35 (77.1%) benign cases, were correctly identified as benign, 6/35 (17.1%) benign cases were incorrectly identified as malignant, and two (5.7%) were found to be inconclusive. In the malignant group, 17 of the 23 patients were identified as having malignancy. Color Doppler showed three (18.8%) benign tumors had a pulsatality index (PI) of <0.8 and 21 malignant tumors had a PI of <0.8. Four benign tumors had an resistive index (RI) of <0.6 and 100% of malignant tumors had an RI <0.6.Conclusion The IOTA classification is a reliable scoring system for adnexal masses, and color Doppler can help to minimize interobserver variation.

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Adnexal Masses: Characterization of Benign Ovarian Lesions

Forstner

Kinkel

2007

MRI and CT of the Female Pelvis

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Pretreatment evaluation of adnexal tumors predicting ovarian cancer

Cited by 4 publications

References 19 publications

Preoperative evaluation of ovarian masses with color Doppler and its correlation with pathological finding

Preoperative evaluation of ovarian masses with color Doppler and its correlation with pathological finding

Validity of ultrasound with color Doppler to differentiate between benign and malignant ovarian tumours

Adnexal Masses: Characterization of Benign Ovarian Lesions

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