Pretreatment Hematologic Findings as Novel Predictive Markers for Facial Palsy Prognosis

Abstract

Pretreatment hematologic findings, which reflect the severity of inflammation and bone marrow dysfunction caused by a virus infection, are useful for predicting the prognosis of facial palsy.

Novel pre‐therapeutic scoring system using patient and haematological data to predict facial palsy prognosis

“…The RHS group comprised 94 patients, of whom 62 had recovered, and 32 had not. The demographic and medical characteristics of these patients are described in detail in our previous report …”

“…As shown in Table , the sensitivity, specificity and AUC of individual items were not sufficiently robust to use them individually as independent factors for predicting prognosis. Thus, we included the item “gender” to the PPP score to bolster the sensitivity and specificity of the tool for predicting palsy prognosis, as our previous report discovered that male patients had a worse prognosis than female patients . Table summarises how we used these items to calculate the PPP‐B score.…”

“…Neurologists typically have used the residual function in the facial nerve as a predictor of facial palsy prognosis, but not the severity of the antecedent viral infection . Previously, we reported that facial palsy prognosis correlated with pre‐treatment complete blood count (CBC) data, which in turn reflect the severity of inflammation and bone marrow dysfunction caused by viral infections …”

“…Recruitment and testing proceeded from January 2010 to December 2014. Inclusion and exclusion criteria were described in a previous report . Briefly, we included facial palsy patients with pre‐treatment haematological test data.…”

“…As in the previous report, patients were divided into two groups. One group (BP group) consisted of patients who were clinically diagnosed with BP, but who did not present with vesicular eruptions or lower cranial nerve symptoms.…”