Prevalence and Antibiogram of Bacterial Uropathogens of Urinary Tract Infections from a Tertiary Care Hospital of Bangladesh

Abstract

Urinary tract infections (UTIs) are one of the most frequently occurring infections majority of which are caused by multi-drug resistant (MDR) uropathogens. Hence, the present study was designed to find out the prevalence of bacterial pathogens causing UTIs and to determine their antibiotic resistance patterns against different classes of antibiotics. Cleancatch midstream urine samples were collected from 200 UTI patients of different sex and age groups. The uropathogens were isolated using Hi-Chrome UTI agar, Blood agar, MacConkey agar and then subjected to antibiotic susceptibility analysis against nine antibiotics of different classes using Kirby-Bauer's disc diffusion method. From 55.08% positive samples, it was found that females were more prone to UTIs than males and in both cases; the prevalence rate was higher in the age group 21-40 years (33%). Among the uropathogens, E.coli was the predominant etiological agent (57.38%) followed by Enterococcus sp. (36.06%), Pseudomonas aeruginosa (3.28%) and Staphylococcus aureus (3.28%). The pathogens showed remarkable amount of sensitivity against Gentamicin and Ciprofloxacin. The present experiment can be helpful for the clinicians in finding proper drugs in the developing countries like Bangladesh where multi-drug resistance problem has just complicated the treatment of UTIs.

Microbiological Profile of Urinary Tract Infections with special Reference to Antibiotic Susceptibility Pattern of Escherichia coli Isolates

“…The current study observed aerobic Gramnegative bacteria were the dominant pathogens with Enterobacteriaceae the predominant pathogens This finding was in agreement with previous studies study done by (Stefaniuk et al, 2016;Kumar et al, 2016 b) This result is in agreement with the previous studies of (Salunke and Gidamudi, 2017;Sanjee et al, 2017;Vranic et al, 2017;Wong et al, 2017) in which similar organisms were isolated, with E.coli was the most prevalent isolate…”

Prevalence of E. coli ST131 among Uropathogenic E. coli Isolates from Iraqi Patients in Wasit Province, Iraq

“…The increase of MDR strains in this study may be the result of several reasons including overuse of antibiotics through their prescription or self-medication without antibiotic sensitivity testing, as well as sharing an antibiotic between family members or friends. Careless usage of antibiotics is the most important factor that facilitates the development of MDR, which triggers the selection and distribution of antibiotic-resistant pathogens in clinical practice [ 24 , 42 ]. To end this problem, Al-Hilali [ 24 ] and Lee et al [ 4 ] suggested that the antimicrobial therapy should be tailored to each patient, taking into consideration the severity of disease, individual and local patterns of antimicrobial resistance, and the potential for collateral damage associated with antimicrobial use.…”

Drug-Resistant Bacterial Infections in HIV Patients

“…UTI accounts for consumption of large proportion of anti-bacterial drugs [18]. Resistance to commonly prescribed antibiotics for UTI is an expanding global problem both in developed as well as developing countries [56]. UTI became quite alarming as isolated uropathogens exhibit high percentage resistance to almost all antibiotics [57].…”