Prevalence and Antibiotic Susceptibility of Staphylococcus Aureus and Other Staphylococcal Infections in Pregnant Women Attending Antenatal Clinic in a Tertiary Hospital in Port Harcourt, Nigeria

Cn, Stanley; Ugboma, Haa; Ibezim, EC; Aa, Attama

doi:10.4172/2332-0877.1000125

Cited by 6 publications

(5 citation statements)

References 38 publications

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“…Similar work done carried out showed 6% resistance to gentamicin and resistance rate of 10.4% to ofloxacin (Rajaduraipandi et al, 2006). A study carried out by Stanley et al (2013) on the antimicrobial susceptibility of S. aureus from isolated pregnant women showed that many were only moderately susceptible to tested antibiotics. In their study levofloxacin, ceftriaxone, clindamycin and erythromycin all appeared in decreasing order (Stanley et al, 2013).…”

Section: Discussionmentioning

confidence: 55%

“…A study carried out by Stanley et al (2013) on the antimicrobial susceptibility of S. aureus from isolated pregnant women showed that many were only moderately susceptible to tested antibiotics. In their study levofloxacin, ceftriaxone, clindamycin and erythromycin all appeared in decreasing order (Stanley et al, 2013). Their work was in agreement with the study carried out by Imade et al (2010), where results obtained suggested ceftriaxone, ciprofloxacin, augumentin, ofloxacin and gentamicin as drugs of choice for S. aureus.…”

Section: Discussionmentioning

confidence: 99%

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Antibiotics Resistance and Plasmid Profile of Staphylococcus aureus from Wound Swabs in Port Harcourt Nigeria

Agbagwa¹,

Jirigwa²

2015

Current Research in Bacteriology

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Staphylococcus aureus are organisms that have been detected as the major pathogens in hospital and community settings that are responsible for infections and their resistance to commonly used antibiotics has become worldwide concern. The indiscriminate use of antibiotics has led to the presence of drug resistant organisms. A total of 100 wound swabs were obtained from two tertiary hospitals in Port Harcourt, Nigeria and screened for S. aureus. This was done by streaking the swab sticks on sterile mannitol salt agar plates, positive growths were identified using conventional methods based on morphological and biochemical characteristics. Identified S. aureus was subjected to antibiotics susceptibility test using Kirby Bauer disc method. Plasmid profiling was also carried out on 30 randomly selected S. aureus using gel electrophoresis. Out of the 100 wound swabs examined, ninety-two were positive for S. aureus. Antibiotic susceptibility testing showed that S. aureus was 100% resistant to caftaxidim, ceftriazone, ofloxacin and ceptazdime. Staphylococcus aureus was sensitive to ofloxacin and gentamicin (88%), erythromycin (84%) and augumentin (82%). Plasmid profile result for S. aureus revealed single plasmid sizes of 2027, 2322 4361 and 23130 bp, respectively while double plasmid size was observed in one isolate. The determination of antibiotic sensitivity pattern and plasmid profiling of S. aureus isolated from wound will assist in the preliminary treatment of wound infections.

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Section: Discussionmentioning

confidence: 55%

Section: Discussionmentioning

confidence: 99%

Antibiotics Resistance and Plasmid Profile of Staphylococcus aureus from Wound Swabs in Port Harcourt Nigeria

Agbagwa¹,

Jirigwa²

2015

Current Research in Bacteriology

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“…Non-pregnant women show a higher rate of Staphylococcus aureus colonisation than postpartum women as revealed by the study. Similarly, a high isolation rate of Staphylococcus aureus in Non-pregnant women than in pregnant women attending a tertiary Hospital in Port Harcourt have also been reported [24]. There was significant difference in the prevalence of Staphylococcus aureus between Non-pregnant women and postpartum women (P= .002).…”

Section: Discussionmentioning

confidence: 63%

Prevalence of Staphylococcus aureus among Female Patients Attending Rivers State University Teaching Hospital (RSUTH) in Port Harcourt, Nigeria

Edubamou¹,

Patience²,

Tonye

2023

AJRID

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Objectives: To isolate, identify and determine the prevalence of Staphylococcus aureus among Female Patients attending Rivers State University Teaching Hospital in Port Harcourt using High Vaginal Swab samples. Methods: A cross-sectional study was carried out on total of 103 female patients attending the outpatients department and Antenatal clinic of Rivers State University Teaching Hospital. High Vaginal Swab samples were aseptically collected from 55 non-pregnant and 48 six weeks postpartum women. These were then analysed in the Microbiology Laboratory of the Hospital, following standard microbiological procedures. Questions on age, number of sexual partners, knowledge of vaginal infection, symptomatic case, History of previous infection and treatments was responded to by each participant through the completing of questionnaires. Mannitol Salt Agar (MSA) was used for the isolation of the organism and their phenotypic traits were determined based on their cultural and biochemical characteristics. Results: The study revealed that 25 (24.3%) consisting of 20 (36.4%) non-pregnant women and 5 (10.4%) Postpartum women were positive for Staphylococcus aureus infection. The prevalence of S. aureus among different groups was statistically significant, (P= .002). The highest percentage of S. aureus isolation (36.4%) was found in non-pregnant population. Prevalence of S. aureus was found highest 10 (18.2%) in 21-25 age group among non-pregnant women and none in 26-30 age group among postpartum women. Data obtained from the questionnaires returned showed that 10 (40%) that tested positive for the organism were asymptomatic as at the time of sample collection, had history of previous reproductive tract infection and had previously undergone treatment. Conclusion: The high rate of vaginal Staphylococcal colonisation observed and the positive correlation between Staphylococus aureus prevalence and age, Child delivery status as well as treatment of previous reproductive tract infection seen in the study suggests the need for awareness on the importance of personal hygiene, proper antibiotic usage and regular screening of females within reproductive age.

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“…Also urine sample was aseptically inoculated on nutrient agar, MacConkey agar, and mannitol salt agar plates using a conventional technique. When the growth of S. aureus in a urine sample is equivalent to or greater than 10 5 colony form unit, significant Staphylococcus aureus bacteriuria is determined [17,6]. A considerable bacteriuria of 10 5 CFU/mL of urine is associated with the presence of 1 bacteria per oil immersion field.…”

Section: Methodsmentioning

confidence: 99%

“…The major risk factors for recurrent urinary tract infection in premenopausal sexually-active women are the onset of symptoms immediately after sexual intercourse, voiding dysfunction, having many sexual partners, spermicides usage for contraception, young age at the first UTI and maternal history of UTI [6].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Methicillin Resistant Staphylococcus aureus Bacteriuria among Pregnant Women Attending Secondary Health Hospitals in Ilorin, Nigeria

Bale

Babatunde

Awe

2021

JAMB

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Background: Urinary tract infection is one of the most frequently acquired infections in both community and hospitals and is common among the adolescents and the old genders. Aim: To determine the prevalence of methicillin resistant Staphylococcus aureus bacteriuria among pregnant women attending secondary health hospitals in Ilorin, Nigeria Study Design: An experimental study which involve a random selection of consented pregnant women. Place and Duration of Study: Department of Biosciences and Biotechnology Kwara State University Malete between January 2018 and June 2019. Methodology: In this study, a total of 856 pregnant women mid stream clean catch early morning voided urine samples for two consecutive days (383 of the samples were collected from Sobi Specialist Hospital, 278 from Adewole Cottage Hospital and 195 collected from Ajikobi Cottage Hospital) were randomly screened for the presence of Staphylococcus aureus bacteriuria using standard microbiological procedures such as growth on mannitol salt agar, Gram reaction, catalase and coagulase tests. The Kirby–Bauer disk diffusion method was used to determine the antibiotic sensitivity profile of S. aureus isolated using oxoid antibiotic discs. Results: Out of 856 samples screened 56 samples (6.5%) showed significant Staphylococcus aureus bacteriuria, 16- 25 years has a prevalence rate of 5.6%, 26- 35 years (5.8%) while 35-45 years have the prevalence rate of 10.9%. A total of 7 (12.5%) methicillin resistant Staphylococcus aureus were isolated. Antibiotic sensitivity profile shows that 26.8% were resistance to gentamicin, 44.6% to tetracycline, 19.6% to chloramphenicol, 33.9 % to erythromycin, 67.9% to amoxicillin, 32% to augmentin, 12.6% to ceftriaxone, 5.3% to ciprofloxacin and 100% susceptibility to both nitrofurantoin and vancomycin. Conclusion: The study shows the high prevalence of MRSA and high susceptibility of nitrofurantoin and vancomycin to all the MRSA isolated.

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Prevalence and Antibiotic Susceptibility of Staphylococcus Aureus and Other Staphylococcal Infections in Pregnant Women Attending Antenatal Clinic in a Tertiary Hospital in Port Harcourt, Nigeria

Cited by 6 publications

References 38 publications

Antibiotics Resistance and Plasmid Profile of Staphylococcus aureus from Wound Swabs in Port Harcourt Nigeria

Antibiotics Resistance and Plasmid Profile of Staphylococcus aureus from Wound Swabs in Port Harcourt Nigeria

Prevalence of Staphylococcus aureus among Female Patients Attending Rivers State University Teaching Hospital (RSUTH) in Port Harcourt, Nigeria

Prevalence of Methicillin Resistant Staphylococcus aureus Bacteriuria among Pregnant Women Attending Secondary Health Hospitals in Ilorin, Nigeria

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