Prevalence and antimicrobial susceptibility patterns of uropathogenic E. coli among people in Zakho, Iraq

Polse, Reem Foad; Yousif, Samira Younis; Assafi, Mahde Saleh

doi:10.18203/2320-6012.ijrms20160813

Cited by 26 publications

(27 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Microorganisms belonging to Enterobacteriaceae family were the most common bacteria isolated from UTI in the current study. For instance E. coli was the most predominant bacteria and similar result was reported by Assafi et al, (2016). The results in this study showed that the urine cultures revealed no bacterial growth even in the case of presence hallmark of UTI.…”

Section: Discussionsupporting

confidence: 88%

Prevalence of Urinary Tract Infections and Their Antimicrobial Sensitivity Among Diabetic and Non Diabetic Patients in Zakho

Jameel

Artoshi

2019

SJUOZ

View full text Add to dashboard Cite

Background: Urinary tract infection (UTI) is one of the most common bacterial infections in diabetics and non-diabetics. Worldwide about one hundred fifty million people are infected with UTI each year. Indifference in diabetes management has been shown to increase the risk of complications. This may lead to different microbial infections including UTI. UTI is often treated with various broad-spectrum antibiotics due to concerns about infection with resistant organisms. Objective: The aim of this study was to determine the prevalence of UTI and antibiotic sensitivity pattern in both diabetic and nondiabetic patients attended the Zakho Emergency Hospital and Chamiskho Health Center at refugee camp in Zakho city. Methods: Midstream urine sample was collected from 316 patients attended Zakho Emergency Hospital and Chamiskho Health Results: 316 samples were collected from diabetic and non-diabetics, 195 (61.70%) sample were collected from diabetics and 121 (38.30%) sample were collected from non-diabetic patients. The frequency of male and female was 101 (31.96%) and 215 (68.04%) respectively. The top five dominant bacteria isolated in this study were Escherichia coli (43.20%), Klebsiella pneumoniae (19.90%), Proteus mirabilis (11.65%), Pseudomonas aeruginosa (8.73%) and Staphylococcus aureus (6.31%). The isolated bacteria were highly sensitive to meropenem (100%) followed by imipenem (97% sensitive) and less sensitive to ciprofloxacine, amikacin and nitrofurantoin. While most of the isolates were resistance to tetracycline (21% sensitive), ampicillin (22% sensitive) and piperacillin (28% sensitive). Conclusion: Analysis of the results showed that urinary tract infection is more prevalence in diabetic than non-diabetics and in female than male. Also, the most commonly isolated bacterium was E. coli. Most isolated pathogens show high resistance to tetracycline and ampicillin.

show abstract

Section: Discussionsupporting

confidence: 88%

Prevalence of Urinary Tract Infections and Their Antimicrobial Sensitivity Among Diabetic and Non Diabetic Patients in Zakho

Jameel

Artoshi

2019

SJUOZ

View full text Add to dashboard Cite

show abstract

“…Thus, the use of these antibiotics as an empirical treatment for a suspected UTI would be the drugs of choice against most common isolated uropathogens. Similar results were observed by other researcher who found the sensitivity of uropathogen to meropenem and imipenem Polse et al, 2016a). However it is recommended that carbapenems should be used as a last line antibiotic to prevent the occurrence of carbapenem resistance (Kiffer et al, 2006).…”

Section: Discussionsupporting

confidence: 85%

Antimicrobial Susceptibility Pattern of Pathogenic Bacteria Causing Urinary Tract Infections at Azadi Hospital In Duhok City\Kurdistan Region of Iraq

Abdulrahman

2018

SJUOZ

View full text Add to dashboard Cite

Urinary tract infections represents one of the most common diseases encountered in medical practice affecting people of all ages from the neonate to the geriatric age group. The aim of this study was to determine and evaluate the antimicrobial susceptibility patterns for most common strains of bacterial urine isolates taken from patients at Azadi teaching hospital laboratories in Duhok city/Kurdistan region in Iraq, for two years (2014 and 2015). A retrospective survey study was conducted and 1003 data of urine culture sensitivity test were collected from recorded archives of the Azadi hospital of two years; 2014 and 2015. The study included all recorded positive urine samples cultures isolated from inpatients and outpatients. Results revealed that the female to male ratio for urinary tract infection was 2.7:1 and the most common microorganisms isolated were Escherichia coli (52%), Staphylococcus aureus (11%), Staphylococcus haemolyticus (9.6%) and Klebsiella pneumoniae (8.1%). In general maximum sensitivity was seen for Meropenem (94.9%), followed by Imipenem (89.7%) and Ertapenem (88.7%). The maximum resistance was seen against Cefazolin (79.7%) and Amoxicillin/clavulanic acid (77.5%). The antibiotic sensitivity pattern of E. coli reveals that the maximum sensitivity was seen for Meropenem (97.3%) and Imipenem (95.6%). The maximum resistance was seen against Amoxicillin/clavlanic acid (83.1%). The resistance against many commonly used antibiotics have been increased which limit the options for treating urinary tract infection. This is resulted from uncontrolled use of the antibiotics and lack of policies and guidelines for their use in public health.

show abstract

“…Since 2004, resistance to cephalosporins has increased seriously for Escherichia coli infections [26]. In addition, parallel findings were obtained from studies carried out in Iraq, Pakistan, and Ethiopia [27][28][29][30]. This study also showed moderate bacterial resistance toward gentamycin, azithromycin, cefoxitin, and ciprofloxacin.…”

Section: Antibiotic Nonsusceptibilitysupporting

confidence: 64%

Antimicrobial Resistance Profiles for Different Isolates in Aden, Yemen: A Cross-Sectional Study in a Resource-Poor Setting

Badulla

Alshakka

Ibrahim

2020

BioMed Research International

View full text Add to dashboard Cite

Background. There is a rapid deterioration in the effectiveness of antibiotics due to the global prevalence of bacterial antimicrobial resistance (AMR). AMR can cause an increase in mortality and morbidity due to treatment failures and a lack of effective therapy. Objective. The purpose of this study was to evaluate the AMR pattern of different bacterial isolates at hospitals and laboratories. Materials and Methods. A cross-sectional study from March 2019 to June 2019 was conducted at different governmental and private hospitals and laboratories in Aden, Yemen. Age, sex, specimen type, bacterial isolates, and antibiotic susceptibility pattern were collected using a data extraction sheet. Descriptive statistics were used for data analysis. Result. Data were recorded for 412 patients from whom 20 clinical specimens were collected and analyzed. The most common bacteria isolated were Staphylococcus spp. (n=172, 41.74%), E. coli (n=164, 39.80%), Pseudomonas spp. (n=37, 8.98%), and Klebsiella pneumoniae (n=18, 4.36%); other bacteria were less common. The overall bacterial resistance was highest against the combination of sulfamethoxazole with trimethoprim (73.12%), followed by amoxicillin and clavulanate (65.19%). The cephalosporin antibiotics also showed high resistance rates. The study also showed moderate bacterial resistance to gentamycin (32.65%), azithromycin (29.92%), cefoxitin (62.65%), and ciprofloxacin (25.60%). Ertapenem (16.67%) and levofloxacin (15.56%) had the lowest resistance rates. Conclusion. There was a high percentage of bacteria resistant to several antibiotics. Antibiotic susceptibility testing is a prerequisite guide for the selection of appropriate antibiotic therapy for bacterial infections.

show abstract

Prevalence and antimicrobial susceptibility patterns of uropathogenic E. coli among people in Zakho, Iraq

Cited by 26 publications

References 25 publications

Prevalence of Urinary Tract Infections and Their Antimicrobial Sensitivity Among Diabetic and Non Diabetic Patients in Zakho

Prevalence of Urinary Tract Infections and Their Antimicrobial Sensitivity Among Diabetic and Non Diabetic Patients in Zakho

Antimicrobial Susceptibility Pattern of Pathogenic Bacteria Causing Urinary Tract Infections at Azadi Hospital In Duhok City\Kurdistan Region of Iraq

Antimicrobial Resistance Profiles for Different Isolates in Aden, Yemen: A Cross-Sectional Study in a Resource-Poor Setting

Contact Info

Product

Resources

About