Prevalence and Associated Dietary Factors of Rome IV Functional Gastrointestinal Disorders in Rural Western Honduras

Global prevalence of functional constipation according to the Rome criteria: a systematic review and meta-analysis

“…In total, seven studies stated that they used the Rome I criteria in 6 separate countries, [16][17][18][19]23,25,40 17 the Rome II criteria in 12 separate countries, [20][21][22][23][24][25][26][27][28][29][30][31]35,36,41,45 18 the Rome III criteria in 14 separate countries, [32][33][34]37,39,[42][43][44][46][47][48][49][50][51][52][53]55,58 and five the Rome IV criteria in 35 separate countries. 9,10,54,56,57 The pooled prevalence of FC, according to the criteria used to define its presence, is provided in Table 1. Pooled prevalence was highest when the Rome I criteria were used (15.3%; 95% CI 8.1% to 24.4%), and lowest when the Rome IV ...…”

“…29 Using the Rome III criteria, prevalence of FC was lowest in Germany at 0.2%, 49 and highest in the Netherlands at 24.5%. 53 Finally, when the Rome IV criteria were used prevalence was lowest in Honduras at 1.1%, 56 and highest in Ghana at 26.1%. 9 The continued disparity in prevalence of FC by country in these analyses suggests that geographical variation was not related solely to the diagnostic criteria used in each study.…”

“…[20][21][22][23]25,26,28,30,35,38 When an interview-administered questionnaire was used the highest prevalence was again found with Rome I in one study (24.3%; 95% CI 20.3% to 28.7%), 18 and lowest with Rome IV in three studies (7.3%; 95% CI 3.8% to 11.8%). 9,54,56…”

Association between genetic polymorphisms of NOD1, Interleukin‐1B, and cagA strain with low‐grade duodenal eosinophilia in Helicobacter pylori‐related dyspepsia

“…However, similar observation was described in other studies in rural or low-resource area in Latin America like Brazil, 66 Mexico, 67 and Honduras. 68 Northeast Argentina can be categorized as a rural or low-resource area, where environmental factors may be associated with this observation. Noteworthy, the virulence genes of H.…”

“…The limitations of the study include (1) population studied: our cohort comprised of rural South-American population of H. pylorirelated functional dyspepsia with high proportion of EPS patients rather than PDS [66][67][68] ; (2) histological evaluation of duodenal samples from D2 only: we choose to evaluate D2 based on previous data where duodenal eosinophilia and degranulation was observed in FD subjects at D2 but not D1 when was compared with healthy controls 48,72 ; (3) our cohort comprised of 98 patients with H.…”