Prevalence and Associated Factors for Suicidal Ideation and Behaviors in Obsessive-Compulsive Disorder

Torres, Albina Rodrigues; Ramos-Cerqueira, Ana Teresa de Abreu; Torresan, Ricardo Cézar; Domingues, Mariana de Souza; Hercos, Ana Carolina R.; Guimarães, Aron Barbosa C.

doi:10.1017/s1092852900015467

Cited by 55 publications

(28 citation statements)

References 25 publications

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“…This finding is in accordance with the work of Torres et al, 27 who reported that depressive symptoms were associated with previous suicidal ideation but not with current suicidal ideation or with suicide attempts. Apter et al 28 even found an inverse relationship between depression and suicidal behavior in a sample of adolescents with OCD.…”

Section: Discussionsupporting

confidence: 93%

Alexithymia, suicidal ideation, and serum lipid levels among drug-naïve outpatients with obsessive-compulsive disorder

Berardis

Serroni

Marini

et al. 2014

Rev. Bras. Psiquiatr.

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Objective: As obsessive-compulsive disorder (OCD) is a relatively common psychiatric disorder with a significant suicide risk, the individuation of potential biomarkers of suicidality, such as cholesterol levels, may enable recognition of at-risk subjects. Therefore, the aims of this study were to: 1) evaluate potential differences in clinical and laboratory parameters between patients with and without alexithymia and compare them with healthy controls; and 2) investigate which clinical and laboratory variables were associated with suicidal ideation. Methods: 79 drug-naïve adult outpatients with a DSM-IV diagnosis of OCD were recruited. Alexithymia was measured with the 20-item Toronto Alexithymia Scale (TAS-20), suicidal ideation was assessed with the Scale for Suicide Ideation, and depressive symptoms were evaluated with the Montgomery-Å sberg Depression Rating Scale (MADRS). Serum lipid levels of 40 healthy controls were also evaluated. Results: Alexithymic patients had altered serum lipid levels in comparison with non-alexithymics and healthy controls. Using a linear regression model, the presence of symmetry/ordering obsessions and compulsions, lower HDL-C levels, and difficulty in identifying feelings dimension of the TAS-20 were associated with higher suicidal ideation. Conclusions: Alexithymic individuals with OCD may exhibit dysregulation of the cholesterol balance, which in turn may be linked to suicidal ideation. Further prospective studies are required to elucidate this potential association.

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Section: Discussionsupporting

confidence: 93%

Alexithymia, suicidal ideation, and serum lipid levels among drug-naïve outpatients with obsessive-compulsive disorder

Berardis

Serroni

Marini

et al. 2014

Rev. Bras. Psiquiatr.

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“…Reported variables had a percentage of missing data ranging from 0 to 22%. with rates of SA between 3 and 27% in OCD patients, 4,[28][29][30][31][32] also considering the most recent Brazilian and Swedish reports documenting rates of 11.7 and 19.4%, respectively. 6,7 It is also noteworthy that, in the present study, significantly higher rates of SA history were reported in OCD patients from Europe and South Africa (40 and 39%, respectively) compared to those from North America and the Middle East (13 and 8%, respectively).…”

Section: Discussionmentioning

confidence: 99%

Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)

et al. 2017

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“…rates of comorbid depression and anxiety rather than OCD itself [10,11], but controlling for comorbidity the risk of suicidality remains substantial among OCD sufferers (de la Cruz et al, 2016). In general, studies have reported high rates of suicidal ideation in OCD ranging between 20% and 46% [11][12][13][14][15]. Another recent study reported that 65% of the OCD patients had endorsed at least one of the questions about suicidal phenomena as positive.…”

Section: Introductionmentioning

confidence: 99%

Comorbidity, age of onset and suicidality in obsessive–compulsive disorder (OCD): An international collaboration

Brakoulias

Starčević

Belloch

et al. 2017

Comprehensive Psychiatry

161

108

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In this large cross-continental study, comorbidity in OCD was common. The high rates of comorbid major depression and anxiety disorders emphasize the need for clinicians to assess and monitor for these disorders. Earlier ages of onset of OCD, specific phobia and social phobia may indicate some relatedness between these disorders, but this requires further study. Although there do not appear to be significant cultural variations in rates or patterns of comorbidity and suicidality, further research using similar recruitment strategies and controlling for demographic and clinical variables may help to determine whether any sociocultural factors protect against suicidal ideation or psychiatric comorbidity in patients with OCD.

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Prevalence and Associated Factors for Suicidal Ideation and Behaviors in Obsessive-Compulsive Disorder

Abstract: Suicidality has been underestimated in OCD and should be investigated in every patient, so that appropriate preventive measures can be taken.

Cited by 55 publications

References 25 publications

Alexithymia, suicidal ideation, and serum lipid levels among drug-naïve outpatients with obsessive-compulsive disorder

Alexithymia, suicidal ideation, and serum lipid levels among drug-naïve outpatients with obsessive-compulsive disorder

Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)

Comorbidity, age of onset and suicidality in obsessive–compulsive disorder (OCD): An international collaboration

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