Prevalence and associated factors of persistent diarrhoea in Iranian children admitted to a paediatric hospital

Abstract

To identify the frequency and associated factors of persistent diarrhoea in a paediatric hospital in Tehran, Islamic Republic of Iran, children admitted with acute diarrhoea were followed prospectively until resolution of the episode. Persistent diarrhoea developed in 19.6% of the 424 diarrhoea cases. Children with persistent diarrhoea were significantly younger than those with acute diarrhoea (15.3 versus 29.4 months). Enteroaggregative Escherichia coli was the most prevalent pathogen in both groups, but otherwise the profile of symptoms and isolated organisms was similar in the 2 groups. History of dietary change prior to admission and use of antibiotics and anticholinergic drugs in the acute phase were significantly higher in the persistent than acute diarrhoea cases.

Human Enteric Pathogens in Eight Rivers Used as Rural Household Drinking Water Sources in the Northern Region of South Africa

“…The most prevalent strains identified included atypical enteropathogenic E. coli (EPEC), followed by enteroaggregative E. coli (EAEC). EPEC has emerged as an important pathogen in outbreaks of acute diarrhoea in developed [58] and developing countries [59,60] and both EPEC and EAEC infections are dangerous in immunocompromised individuals and children [61][62][63]. A study by Traore et al [5] on some of the rivers in the Venda region detected several pathogenic strains of E. coli, such as enteroinvasive E. coli (EIEC), enterotoxigenic E. coli (ETEC), and enteropathogenic E. coli (EPEC), which are strains that are known for causing diarrhoea in children [24] and that was also detected in this study.…”

Prevalence of enteroaggregative Escherichia coli among children with gastroenteritis in the northwest of Iran

“…Since that, sporadic and outbreaks of acute and persistent diarrhea in different parts of the world (developing and developed countries) have been reported. [5][6][7][8][9][10] Ahangarzadeh-Rezaee M, et al, J Anal Res Clin Med, 2015, 3 To investigate the prevalence of enteroaggregative Escherichia coli (EAEC) in children < 10 years with a diagnosis of gastroenteritis by multiplex polymerase chain reaction (MPCR).…”

Neurological Manifestaions in Acute Onset of Viral Gastroentritis

“…Rota virus antigen obtained from stool of AGE cases between 15-47% of hospitalized children with AGE, just in 12% of controls group. Adenovirus and astrovirus obtained from stool of Iranian children with AGE [11][12][13][14][15][16][17][18][19][20][21]. Saderi et al reported the incidence of enteric adenoviruses in Iranian children.…”

“…6.7% of stool specimens contained enteric adenoviruses (3.3% Ad40 and 3.4% Ad41) and 2.0% nonenteric adenoviruses [14]. In countries such as Iran, which rotavirus vaccination in not used knowledge of viral ethnological pathogens of AGE is very important in planning diarrhea disease control strategies [15][16][17][18][19]. It might be useful for future vaccine development in the region.…”

“…AGE is a common cause for hospital admission in Iranian children [11][12][13][14][15][16]. Rota virus antigen obtained from stool of AGE cases between 15-47% of hospitalized children with AGE, just in 12% of controls group.…”