Prevalence and associated factors of depression among people with epilepsy in Mekelle, Tigray, Ethiopia, 2019.

Seid, Jemal; Mebrahtu, Kalayu

doi:10.21203/rs.3.rs-17990/v1

Cited by 3 publications

(3 citation statements)

References 28 publications

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“…In this study the magnitude of depression among epileptic patient was 49.2%, which is in line with the study done in Northwest Ethiopia (45.2%) (4) and Nigeria (45%) (29). But the result of this study was higher than the study conducted in Mekelle Ethiopia(34.8%) (34), in Central Ethiopia(43.8%) (16), Thailand (38.5%) (43) and Egypt (25.5%) (44). The observed difference might be due to difference in data collection tools, cutoff points, study areas and cultures of the study participants.…”

Section: Discussionsupporting

confidence: 88%

“…According to previous study factors for occurrence of depression among patients with epilepsy were female gender, low educational status (26, 27, 28, 29), uncontrolled seizure (25), presence of frequent seizures, long duration of epilepsy and poor compliance to antiepileptic drug (22), cannot read and write (20,31,32), poor medication adherence, frequency of seizure, having developed perceived stigma, contagious belief, heritability belief & treatability belief of the patients was associated with co-morbid depression (30,33,34,35).…”

Section: Introductionmentioning

confidence: 98%

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Depression and associated factors among people with epilepsy at Wolaita Sodo University Hospital, South Ethiopia

Berhanu,

Yigzaw,

Tinsae

et al. 2024

Preprint

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Background Epilepsy is the most common neurological disorder in the world and contributed to various psychiatric illnesses. Depression is one of the most frequent co morbid psychiatric disorders that affect the quality of life in patients with epilepsy. Despite this impact depression continues to be under-recognized and undertreated. Therefore this study amid to assess the magnitude of depression and its associated factors among patients with epilepsy at Wolaita sodo university hospital, South Ethiopia 2021. Methods A hospital based cross sectional study was conducted from April 2021-May 2021. A systematic random sampling technique was used to select 423 samples of patients with epilepsy and interviewer administrated structured questionnaires was employed. Patient Health Questionnaire with 9-items was used to assess depression. Logistic regression model was used to determine the association between the outcome and independent variables. A 95% CI and Odds ratio with corresponding p-value < 0.05 were used to determine the strength of association. Result The overall magnitude of depression among epileptic patients in this study was 49.2%. Educational status; unable to read and write (AOR = 3.43, 95%CI:1.09,10.7), being female (AOR = 2.54, 95%CI:1.43,4.52), perceived stigma (AOR = 5.96, 95%CI:2.88,12.3), poor social support (AOR = 2.88, 95%CI:1.28, 6.48), poor medication adherence (AOR = 4.60, 95%CI: 2.46,8.63), seizure frequency of 6 times per month (AOR = 5.59, 95%CI:1.72, 18.1) were independent predictors of depression among patients with epilepsy at p-value < 0.05. Conclusion and recommendation: In this study nearly half of the patient with epilepsy had depression. Educational status; unable to read and write, being female, perceived stigma, poor social support, poor medication adherence, seizure frequency of 6 times per month were independent predictors of depression among patients with epilepsy. Therefore screening depression in epileptic patients and appropriate management critically needed attention to reduce the effects of the problems.

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Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 98%

Depression and associated factors among people with epilepsy at Wolaita Sodo University Hospital, South Ethiopia

Berhanu,

Yigzaw,

Tinsae

et al. 2024

Preprint

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show abstract

“…Depression was measured by the nine items of the Patient Health Questionnaire (PHQ-9), validated in Ethiopia with Cronbach's alpha of 0.84 (22,23). Scores for each item are 0, "not at all"; 1, "several days"; 2, "more than half days" to 3, "nearly every day" with a total score ranging from 0 to 27.…”

Section: Data Collection Procedures and Measurementsmentioning

confidence: 99%

Depression and anxiety among people with hypertension on follow-up in Eastern Ethiopia: A multi-center cross-sectional study

Abdisa

Letta²,

Nigussie³

2022

Front. Psychiatry

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BackgroundPeople with hypertension have a high risk of developing mental disorders, such as depression and/or anxiety. However, there is a paucity of data regarding comorbid depression and anxiety symptoms among people with hypertension in study settings.ObjectiveThe study determined the prevalence and associated factors of depression, and anxiety symptoms among people with hypertension on follow-up at public hospitals, in Eastern Ethiopia.Materials and methodsA cross-sectional study was carried out among 471 people with hypertension who were randomly chosen from four public hospitals in Harar town and the Dire Dawa Administration. The data were collected by interviewer-administered structured questionnaires. A validated nine-item Patient Health Questionnaire and Generalized Anxiety Disorder scales were used to assess depression and anxiety symptoms, respectively. A logistic regression model was used to identify the association among depression, anxiety, and their predictors. An adjusted odds ratio and a 95% confidence interval were used to report the association. The statistical significance was set at a p-value of < 0.05.ResultsDepression and anxiety symptoms were present in 27.2 and 32.7% of people with hypertension, respectively. Being women (AOR = 1.74, 1.09–2.78), having no formal education (AOR = 2.19, 1.19–4.81), presence of other medical illnesses (AOR = 2.23, 1.39–3.56), having a family history of depression (AOR = 2.01, 1.25–3.19), and poor social support (AOR = 2.80, 1.60–5.22) were statistically associated with depressive symptoms, whereas being women (AOR = 1.54, 1.01–2.35), widowed and divorced (AOR = 2.22, 1.41–3.52), presence of other medical illnesses (AOR = 1.64, 1.06–2.53), and poor social support (AOR = 3.54, 2.09–6.01) were statistically associated with anxiety symptoms.ConclusionMore than a quarter of people with hypertension reported symptoms of depression and anxiety. Findings demonstrated that being a woman, having an additional medical illness and having poor social support were statistically associated with depressive and anxiety symptoms. Regular screening, early detection, and offering the proper intervention should be on top priorities for healthcare professionals.

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Psychiatric comorbidity in people with epilepsy in Ethiopia: Systematic review and meta-analysis

Tinsae,

Shumet,

Melkam

et al. 2024

Epilepsy & Behavior

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Prevalence and associated factors of depression among people with epilepsy in Mekelle, Tigray, Ethiopia, 2019.

Cited by 3 publications

References 28 publications

Depression and associated factors among people with epilepsy at Wolaita Sodo University Hospital, South Ethiopia

Depression and associated factors among people with epilepsy at Wolaita Sodo University Hospital, South Ethiopia

Depression and anxiety among people with hypertension on follow-up in Eastern Ethiopia: A multi-center cross-sectional study

Psychiatric comorbidity in people with epilepsy in Ethiopia: Systematic review and meta-analysis

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