Prevalence and Associated Factors of Overactive Bladder in Korean Children 5-13 Years Old: A Nationwide Multicenter Study

Chung, Jong Shik; Lee, Sang Don; Kang, Dong Il; Kwon, Dong Deuk; Kim, Kun Suk; Kim, Su Yung; Kim, Han Gwun; Moon, Du Geon; Park, Kwan Hyun; Park, Yong Hoon; Pai, Ki Soo; Suh, Hong Jin; Lee, Jung Won; Cho, Won Yeol; Ha, Tae Sun; Han, Sang Won

doi:10.1016/j.urology.2008.06.063

Cited by 94 publications

(93 citation statements)

References 16 publications

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“…2 According to two fairly recent, large-scale studies, the prevalence of OAB in children is in the 15-20% range. [3][4] Those studies both reported a higher prevalence of OAB in boys. Chung et al noted a decreasing prevalence of OAB with age, from 23.0% at five years old down to 12.2% at 13 years old.…”

Section: Introductionmentioning

confidence: 94%

Overactive bladder in children

Ramsay¹,

Bolduc²

2017

CUAJ

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Overactive bladder (OAB) is a highly prevalent disorder in the pediatric population. This condition is especially troublesome for pediatric patients and their families when associated with incontinence, since it negatively affects self-esteem and impairs children's development. From the patient's perspective, urgency and urge incontinence can have a significant impact, negatively affecting their quality of life. For a therapy to have true benefit, changes must not only be statistically significant, but must also be perceived as meaningful by the patient. A stepwise approach is favoured to treat this pathology, starting with behavioural therapy, followed by medical management, and eventually more invasive procedures.Antimuscarinic agents are the mainstay of medical treatment for OAB. Oxybutynin is the most commonly used antimuscarinic in the pediatric population. However, some patients have a suboptimal response to antimuscarinics and many experience bothersome side effects, which have been documented with all antimuscarinics to a significantly higher degree than placebo. Although there have been reports about the use of tolterodine, fesoterodine, trospium, propiverine, and solifenacin in children, to date, only oxybutynin has been officially approved for pediatric use by medical authorities in North America. This review will address alternative treatment options for pediatric patients presenting with OAB, from conservative measures to more invasive therapies.

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Section: Introductionmentioning

confidence: 94%

Overactive bladder in children

Ramsay¹,

Bolduc²

2017

CUAJ

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“…In children, the prevalence of LUTS peaks at age 5 to 7 years and then declines with increasing age up to 13 to 14 years. [7][8][9][10]20 The decline in prevalence has been attributed to the maturation of urinary bladder function along with the growth and development of children. Our study is the first to provide evidence that LUTS prevalence rises from the trough at the onset of adolescence and continues to increase throughout adolescence into adulthood.…”

Section: Discussionmentioning

confidence: 99%

“…2,[17][18][19] Only 2.9% of our control subjects had urgency suggestive of overactive bladder (OAB) according to ICCS definitions, 6 in contrast to 12% of Korean children aged 13 years. 20 Children with OAB may have urinary frequency in addition to urgency. The much lower prevalence of urgency than urinary frequency in our study suggests that many of our study subjects had urinary frequency unrelated to OAB.…”

Section: Discussionmentioning

confidence: 99%

Population-based survey of the prevalence of lower urinary tract symptoms in adolescents with and without psychotropic substance abuse

Tam¹,

Ng²,

Wong³

et al. 2016

Hong Kong Med J

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Objective: To investigate the prevalence of lower urinary tract symptoms in adolescents and the effects of psychotropic substance use. Methods:This was a population-based crosssectional survey using a validated questionnaire in students from 45 secondary schools in Hong Kong randomly selected over the period of January 2012 to January 2014. A total of 11 938 secondary school students (response rate, 74.6%) completed and returned a questionnaire that was eligible for analysis. Individual lower urinary tract symptoms and history of psychotropic substance abuse were documented.Results: In this study, 11 617 non-substance abusers were regarded as control subjects and 321 (2.7%) were psychotropic substance users. Among the control subjects, 2106 (18.5%) had experienced at least one lower urinary tract symptom with urinary frequency being the most prevalent symptom (10.2%). Females had more daytime urinary incontinence (P<0.001) and males had more voiding symptoms (P=0.01). Prevalence of lower urinary tract symptoms increased with age from 13.9% to 25.8% towards young adulthood and age of ≥18 years (P<0.001). Among the substance users, ketamine was most commonly abused. Substance users had significantly more lower urinary tract symptoms than control subjects (P<0.001). In multivariate analysis, increasing age and psychotropic substance population have incurred significant costs to the health care system. In children, the association of LUTS with urinary tract infection, persistent vesicoureteric reflux, renal scarring, and constipation have drawn substantial attention over the years. 3,4 Among various LUTSs, urinary incontinence (UI) has been most extensively investigated in children with the reported prevalence varying from 1.8% to ORIGINAL ARTICLE abuse increased the odds for lower urinary tract symptoms. Non-ketamine substance users and ketamine users were respectively 2.8-fold (95% confidence interval, 2.0-3.9) and 6.2-fold (4.1-9.1) more likely than control subjects to develop lower urinary tract symptoms. Females (odds ratio=9.9; 95% confidence interval, 5.4-18.2) were more likely to develop lower urinary tract symptoms than males (4.2; 2.5-7.1) when ketamine was abused. Conclusions:Lower urinary tract symptoms are prevalent in the general adolescent population. It is important to obtain an accurate history regarding psychotropic substance use when treating teenagers with lower urinary tract symptoms.

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“…Puede influir el retraso en el entrenamiento de esfínteres 23 o, al contrario, un control excesivamente temprano e incompleto 17 . -Conductuales: diversos autores relacionan los problemas de conducta y comportamiento con la presencia de alteraciones miccionales, aunque sin poder establecer si son causa o consecuencia 22 .…”

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“…Un recto ocupado de heces empuja a la vejiga y desvía el cuello vesical entorpeciendo el vaciado vesical; además, las heces almacenadas incrementan la actividad de la musculatura del suelo pélvico, dificultando la relajación que se requiere para la micción. -Sociales: la dificultad para acceder al aseo o la higiene defectuosa de los baños están relacionadas con una mayor frecuencia de estreñi-miento y de alteraciones miccionales en los escolares 23,27 . -Por último, citar que los acontecimientos estresantes pueden provocar incontinencia o trastornos de modo secundario (es decir, una vez alcanzada la continencia y tras un período de normalidad): situación familiar conflictiva, problemas escolares, nacimiento de un hermano, cambio de cuidadores, abuso sexual, etc.…”

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Incontinencia y trastornos miccionales: ¿qué podemos hacer?

González¹,

Fernández

2009

Rev Pediatr Aten Primaria

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Resumen Las alteraciones relativas a la micción son un motivo de consulta cada vez más frecuente en pediatría. Pueden referirse tanto a problemas del patrón miccional diurno como a incontinencia. Las infecciones urinarias de repetición también Rev Pediatr Aten Primaria. 2009;11:e1-e29 Miguel Ángel San José González, miguel.san.jose.gonzalez@sergas.es Los autores declaran no presentar posibles conflictos de intereses en relación con la preparación y publicación de este artículo.

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Prevalence and Associated Factors of Overactive Bladder in Korean Children 5-13 Years Old: A Nationwide Multicenter Study

Cited by 94 publications

References 16 publications

Overactive bladder in children

Overactive bladder in children

Population-based survey of the prevalence of lower urinary tract symptoms in adolescents with and without psychotropic substance abuse

Incontinencia y trastornos miccionales: ¿qué podemos hacer?

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