Prevalence and associated factors of hypertension complications among hypertensive patients at University of Gondar Comprehensive Specialized Referral Hospital

Kifle, Zemene Demelash; Adugna, Meaza; Chanie, Gashaw Sisay; Mohammed, Abdulwase

doi:10.1016/j.cegh.2021.100951

Cited by 5 publications

(3 citation statements)

References 56 publications

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“…These results are consistent with those of previous clinical studies. A long-term phase 3 study with a multicenter, open-label design reported that CS-3150 2.5 mg/day or 5 mg/day for 12 or 28 weeks significantly decreased sitting SBP and DBP in patients with Primary hypertension [ 26 ]. A post-hoc analysis also demonstrated that CS-3150 improved night-time BP and N-terminal pro-B-type natriuretic peptide, which is a cardiovascular risk marker, based on different nocturnal BP dipping patterns (dippers, extreme dippers, non-dippers, and risers) [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

Efficacy and safety of esaxerenone (CS-3150) in primary hypertension: a meta-analysis

Sun,

Li,

et al. 2024

J Hum Hypertens

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This study aimed to assess the efficacy and safety of esaxerenone (CS-3150) in treating primary hypertension. PubMed (Medline), Cochrane Central Register of Controlled Trials (CENTRAL), and Embase databases were searched for articles published until April 18, 2023. The outcomes included were diastolic blood pressure (DBP), systolic blood pressure (SBP), 24 h DBP, 24 h SBP, and adverse events. The meta-analysis was conducted using RevMan 5.3. This study included three trials. CS-3150 5 mg had a greater effect on lowering the SBP, DBP, 24 h SBP, and 24 h DBP than either CS-3150 2.5 mg or eplerenone 50 mg. In contrast, CS-3150 2.5 mg and eplerenone 50 mg showed no significant difference in lowering DBP, SBP, 24 h DBP, and 24 h SBP. Moreover, adverse events occurred at comparable rates in the three groups. CS-3150 (especially CS-3150 5 mg) is an effective and safe treatment for primary hypertension; which can reduce blood pressure and alleviate hypertensive symptoms.

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Section: Discussionmentioning

confidence: 99%

Efficacy and safety of esaxerenone (CS-3150) in primary hypertension: a meta-analysis

Sun,

Li,

et al. 2024

J Hum Hypertens

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“…It is characterized by increased force exerted by circulating blood through the walls of the major blood vessels in the body [ 1 ]. Although it often has no symptoms, the consequences are devastating that can lead to heart disease, stroke, vision loss, kidney failure and other serious complications [ 2 , 3 ]. The global burden of diseases report on mortality due to non-communicable diseases indicated that hypertension is the major cause of premature death.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of community-based interventions for prevention and control of hypertension in sub-Saharan Africa: A systematic review

Mengesha,

Tesfaye,

Boltena

et al. 2024

PLOS Glob Public Health

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Hypertension poses a significant public health challenge in sub-Saharan Africa due to various risk factors. Community-based intervention for prevention and control of hypertension is an effective strategy to minimize the negative health outcomes. However, comprehensive systematic review evidence to inform effective community-based interventions for prevention and control of hypertension in low resource settings is lacking. This study aimed to synthesize the effectiveness of community-based interventions on prevention and control of hypertension in sub-Saharan Africa. A comprehensive search for studies was carried out on PubMed, CINAHL, Web of Science Core Collection, Embase, Scopus, and Google scholar databases. The result of the review was reported according to PRISMA guidelines. Studies published in English language were included. Two independent reviewers conducted critical appraisal of included studies and extracted the data using predefined excel sheet. Experimental, quasi experimental, cohort and analytical cross-sectional studies conducted on adults who have received community-based interventions for prevention and controls of hypertension in sub-Saharan Africa were included. In this systematic review, a total of eight studies were included, comprising of two interventional studies, two quasi-experimental studies, three cohort studies, and one comparative cross-sectional study. The interventions included health education, health promotion, home-based screening and diagnosis, as well as referral and treatment of hypertensive patients. The sample sizes ranged from 236 to 13,412 in the intervention group and 346 to 6,398 in the control group. This systematic review shows the effect of community-based interventions on reduction of systolic and diastolic blood pressure. However, the existing evidence is inconsistence and not strong enough to synthesize the effect of community-based interventions for the prevention and control of hypertension in sub-Saharan Africa. Hence, further primary studies need on the effect of community-based interventions for the prevention and control of hypertension in sub-Saharan Africa. Systematic review registration number: PROSPERO CRD42022342823.

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“…The incidents of CVD are caused mainly by a patient's failure to comply with hypertension medication and uncontrolled high blood pressure (1). Globally, 17 million deaths are caused by cardiovascular disease, 9.4 million of which are caused by complications due to hypertension (2). Additionally, 2 million cases of hemorrhagic stroke, 1.5 million cases of ischemic stroke, and 4.9 million cases of ischemic heart disease are caused by hypertension (3).…”

Section: Introductionmentioning

confidence: 99%

Level of Knowledge of Hypertension Patients and Compliance with Treatment at Sirnajaya Health Center

Ramadhani,

Nasution

2023

MMJ

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Background: Uncontrolled hypertension is the most common and important risk factor for cardiovascular diseases, which can lead to complications or even death. Uncontrolled hypertension can be caused by noncompliance with hypertension medication instructions. One factor contributing to the disobedience of hypertension medication instructions is the level of knowledge on hypertension. Purposes: This study analyzed the correlation between patients’ hypertension knowledge and hypertension medication compliance in Sirnajaya Health Center, Bekasi, West Java, Indonesia. Methods: A cross-sectional study was conducted among 62 hypertension patients in Sirnajaya Health Center in December 2022. They were asked to answer the Hypertension Knowledge-Level Scale (HK-LS) questionnaire and the Morisky Medication Adherence Scale-8 (MMAS-8) to assess their hypertension knowledge and compliance with the hypertension medication. The chi-squared test was used to determine the correlations between the variables. Results: There were 36 respondents (58.1%) with low knowledge and 39 respondents (62.9%) with low medication compliance. Analysis through the chi-squared test reveals a correlation between knowledge level and medication compliance (p <0.001). Conclusion: There was a correlation between hypertension knowledge and compliance in consuming hypertension medication among the hypertension patients of Sirnajaya Health Center, Bekasi, West Java, Indonesia.

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Prevalence and associated factors of hypertension complications among hypertensive patients at University of Gondar Comprehensive Specialized Referral Hospital

Cited by 5 publications

References 56 publications

Efficacy and safety of esaxerenone (CS-3150) in primary hypertension: a meta-analysis

Efficacy and safety of esaxerenone (CS-3150) in primary hypertension: a meta-analysis

Effectiveness of community-based interventions for prevention and control of hypertension in sub-Saharan Africa: A systematic review

Level of Knowledge of Hypertension Patients and Compliance with Treatment at Sirnajaya Health Center

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